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Animal Diseases 2023年第4期3卷 275-285页

作者： Aikebaier Reheman xiaojian Cao Yifan Wang xi Nie Gang Cao Wei Zhou Bing Yang Yingying Lei Weipan Zhang Muhammad Ahsan Naeem xi Chen state Key laboratory of Agricultural Microbiology College of Veterinary MedicineHuazhong Agricultural UniversityWuhan 430070China College of Animal Science and Technology Tarim UniversityAlar 843300China Bio-Medical Center Huazhong Agricultural UniversityWuhan 430070China Department of Basic Sciences(Pharmacology) University of Veterinary and Animal Sciences(Narowal Campus)Lahore 54000Pakistan

Mycobacterium tuberculosis(***)can replicate in the macrophage by interfering with many host protein *** it is far from known these host proteins for controlling *** ***,we infected macrophages including THP-1 and Raw264.7 cells with *** and identified the differentially expressed genes(DEGs)in the interferon signaling *** them,2'-5'oligoadenylate synthetase-like(OASL)underwent the greatest upregulation in ***-infected *** of the expression of OASL attenuated *** survival in ***,bioinformatics analysis revealed the potential interaction axis of OASL-TAB3.RvO127,which was further validated by the yeast-two-hybrid(Y2H)assay and *** interaction axis might regulate the *** survival and proliferation in *** study reveals a possible role of OASL during *** infection as a target to control its propagation.

关键词： Mycobacterium tuberculosis Interferon Interferon stimulated genes OASL

Study of nano-manipulation approach based on the least action principle using AFM based robotic system

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Study of nano-manipulation approach based on the least actio...

第3.届中国控制会议

作者： Shuai Yuan Lianqing Liu Zhidong Wang Ning xi Yuechao Wang state Key Lab.Robot. SIA.Chinese Academy of Sciences Shenyang Jianzhu university Graduate university of the Chinese Academy of Sciences Dept.of Advanced Robotics Chiba Institute of Technology Dept.of Industrial and Manufacturing Systems Engineering Emerging Technologies InstituteUniversity of Hong Kong

ISBN: (纸本)9781538629185

Atomic force microscopy（AFM） is originally used to observe the sample surface,and then extended to the area of *** can be quite valuable in the further study of maneuvering *** of the influence of the tip morphology on the tip pushing direction,it is difficult to establish an effective operating model for stably manipulating nanoparticles with controllable manipulation *** resolve this problem,the acting force of manipulating the nano-particle is analyzed firstly based on the least action *** the influence of the contact point between the nano-particle and the tip is taken into account on the pushing direction,and manipulation of the nano-particle is modeled to predict its position after ***,the model parameter is calibrated through several ***,the proposed model is verified by assembling the *** experimental results illustrate that the model can effectively predict the nano-particle position after maneuvering,and can improve the manipulation efficiency.

关键词： Least action principle AFM Nano-manipulation

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基于CEEMD-LSTM光伏短期功率预测

科学技术与工程 2024年第13期24卷 5396-5405页

作者：梁亚峰马立红邱剑洪冯在顺何雷震刘承锡海南能源发展研究院(电网规划设计研究中心) 海口570100 海南电网有限责任公司三沙供电局三沙573100 武汉大学电气与自动化学院武汉430072

为解决传统机器学习方法在面对多变的环境因素和不平稳序列时导致光伏功率预测精度低的问题,提出一种基于完全经验模态分解(complete ensemble empirical mode decomposition,CEEMD)和长短期记忆神经网络(long short-term memory,LSTM)... 详细信息

为解决传统机器学习方法在面对多变的环境因素和不平稳序列时导致光伏功率预测精度低的问题,提出一种基于完全经验模态分解(complete ensemble empirical mode decomposition,CEEMD)和长短期记忆神经网络(long short-term memory,LSTM)相结合的光伏短期功率预测模型。首先,充分考虑影响光伏出力的太阳辐照度、相对湿度、大气压力和空气温度4种环境因素,通过CEEMD将气象因素特征曲线分解为多模态特征数据,准确捕捉其不同的时间尺度和频率特征,进而充分保留环境数据的不平稳特征。其次,在此基础上,利用LSTM网络对多模态特征数据进行时间序列建模,旨在保留时间序列的季节性和不平稳特征,为后续建模提供更准确的输入特征。最后,通过对分解后的信号开展训练,根据输入数据的变化自适应调整预测模型参数,迭代生成特定场景下的预测模型,从而灵活应对实时环境变化,得到相应功率预测结果。在海南一孤立海岛分布式光伏电站3. kW子阵的8个月气象和功率数据集进行验证,实验结果表明,所提方法在保留环境数据细节和局部特性上具有显著优势,在不同气象条件均具有良好的自适应性,有效提高了光伏短期功率预测精度。

关键词：光伏发电完全经验模态分解长短期记忆神经网络光伏短期功率预测不平稳特征多模态特征数据

NIR-IIb excitable bright polymer dots with deep-red emission for in vivo through-skull three-photon fluorescence bioimaging

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Nano Research 2020年第10期13卷 2632-2640页

作者： Nuernisha Alifu Abudureheman Zebibula Hequn Zhang Huwei Ni Liang Zhu Wang xi Yalun Wang Xueliang Zhang Changfeng Wu Jun Qian School of Medical Engineering and Technology xinjiang Medical Universiy Urumqi 830011China state Key laboratory of Modern Optical Instrumentations Centre for Optical and Electromagnetic ResearchCollege of Optical Science and Engineering Zhejiang UniversityHangzhou 310058China Department of Urology Sir Run-Run Shaw Hospital College of MedicineZhejiang UniversityHangzhou 310016China Interdisciplinary Institute of Neuroscience and Technology the Second Afiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310020China Department of Biomedical Engineering South University of Science and TechnologyShenzhen 518055China

It is of great significance to study the brain structure and function in deep-tissue for neuroscience research and bio-medical applications because of the urgent demand for precise ***-photon fluorescence microscopic(3.FM)bioimaging excited by the light in near-infrared IIb(NIR-IIb,1,500–1,700 nm)spectral region is one of the most promising imaging techniques with the advantages of high spatial resolution,large imaging depth,and reduced ***,a type of NIR-IIb light excitable deep-red emissive semiconducting polymer dots(P-dots)with bright 3.F and large three-photon absorption cross-section(σ3.at 1,550 nm was *** the P-dots were functionalized with polystyrene polymer polystyrene graft ethylene oxide functionalized with carboxyl groups(PS-PEG-COOH)and modified with NH2-poly(ethylene glycol)(PEG)to synthesis photochemically stable and biocompatible P-dots nanoparticles(NPs).Further the P-dots NPs were utilized for in vivo 3.FM bioimaging of cerebral vasculature with and without the brain skull under 1,550 nm femtosecond(fs)laser *** vivo 3.FM bioimaging of the mice cerebral vasculature at various vertical depths was ***,a vivid three-dimensional structure of the mice vascular architecture beneath the skull was *** the depth of 3.0μm beneath the brain skull,3.8μm blood vessels could still be clearly ***-IIb excitable P-dots assisted 3.FM bioimaging has great potential in accurate deep tissue bioimaging.

关键词： semiconducting polymer dots(P-dots) near-infrared IIb(NIR-IIb) three-photon fluorescence microscopic(3.FM)bioimaging cerebral vasculature through-skull

Noise-assisted MEMD based relevant IMFs identification and EEG classification

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Journal of Central South university 2017年第3期24卷 599-608页

作者： SHE Qing-shan MA Yu-liang MENG Ming xi Xu-gang LUO Zhi-zeng Institute of Intelligent Control and Robotics Hangzhou Dianzi University Hangzhou 310018 China

Noise-assisted multivariate empirical mode decomposition(NA-MEMD) is suitable to analyze multichannel electroencephalography(EEG) signals of non-stationarity and non-linearity natures due to the fact that it can provide a highly localized time-frequency *** a finite set of multivariate intrinsic mode functions(IMFs) decomposed by NA-MEMD,it still raises the question on how to identify IMFs that contain the information of inertest in an efficient way,and conventional approaches address it by use of prior *** this work,a novel identification method of relevant IMFs without prior information was proposed based on NA-MEMD and Jensen-Shannon distance(JSD) measure.A criterion of effective factor based on JSD was applied to select significant IMF *** each decomposition scale,three kinds of JSDs associated with the effective factor were evaluated:between IMF components from data and themselves,between IMF components from noise and themselves,and between IMF components from data and *** efficacy of the proposed method has been demonstrated by both computer simulations and motor imagery EEG data from BCI competition IV datasets.

关键词： multichannel electroencephalography noise-assisted multivariate empirical mode decomposition Jensen-Shannondistance brain-computer interface

Characteristic of Near-surface Microstructure and Its Effects on the Torsion Performance of Cold Drawn Pearlitic Steel Wires for Bridge Cables

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Journal of Wuhan university of Technology(Materials Science) 2022年第5期37卷 992-999页

作者： ZHANG Fan MAO xinping BAO Siqian ZHAO Gang ZHAO Sixin DENG Zhaojun HE Meng HUANG Fangyu QU xi The state Key laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430081China Baosteel Central Research Institute Wuhan430080China Key laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan430081China

The characteristic of near-surface microstructure and its effects on the torsion performance of cold-drawn pearlitic steel wires for bridge cables were investigated by focused ion beam-scanning electron microscope,transmission electron microscopy and differential scanning *** samples with similar tensile strength before and after hot-dip galvanizing process are,respectively,characterized as delaminated and non-delaminated in torsion test which indicates that the tensile strength is independent of the toughness value(i e,reduction area and torsion ability).It is interesting to find that there exists submicron granular ferrite on near-surface of the wires,which can be attributed to dislocation rearrangement and sub-grains rotation during cold drawing and hot-dip galvanizing *** their distribution can suggest homogeneousness of deformation degree to a certain extent:the closer to the surface of their distribution,the more homogeneous deformation of the *** is a close relationship between the thermal stability of the cementite layer and distribution of granular ferrite:differential scanning calorimetry(DSC)analysis shows that the sample is accompanied by submicron granular ferrite which is located closer to the surface has higher thermal stability under galvanizing temperature(450°C).A new mechanism of the torsion delamination of pearlitic steel wires is discussed in terms of the thermal stability of the cementite layer and distribution of granular ferrite.

关键词： cold-drawn pearlite steel wires torsion performance near-surface microstructure submicron granular ferrite

基于MPLS-VPN构筑电子政务系统的网络平台

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计算机工程与应用 2003年第10期39卷 43-45页

作者：林锦贤沈钧毅西安交通大学计算机科学与技术系西安710049

论文分析了电子政务系统对基础网络平台的需求特征,指出当前电子政务网络平台建设存在的问题,提出基于MPLS-VPN构筑电子政务系统网络平台的解决方法。

关键词： MPLS-VPN 电子政务系统网络平台城域网广域网计算机网络电子化政府

机器学习算法在静脉血栓栓塞症防治中的研究进展

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国际呼吸杂志 2024年第1期44卷 98-103页

作者：席霖枫杨浩宇刘敏翟振国王辰首都医科大学中日友好临床医学院北京100069 北京大学中日友好临床医学院北京100191 中日友好医院放射诊断科北京100029 国家呼吸医学中心、呼吸和共病全国重点实验室、国家呼吸疾病临床研究中心、中国医学科学院呼吸病学研究院、中日友好医院呼吸与危重症医学科北京100029

机器学习(ML)作为人工智能的重要分支,现已广泛应用于疾病诊断和评估。静脉血栓栓塞症(VTE)是一种常见的血栓性疾病,临床诊疗过程需要精确高效的评估策略。随着医工交叉逐渐深入和ML方法学的不断优化,在VTE预防诊治领域,ML发挥着越来越... 详细信息

机器学习(ML)作为人工智能的重要分支,现已广泛应用于疾病诊断和评估。静脉血栓栓塞症(VTE)是一种常见的血栓性疾病,临床诊疗过程需要精确高效的评估策略。随着医工交叉逐渐深入和ML方法学的不断优化,在VTE预防诊治领域,ML发挥着越来越重要的作用,相关研究取得显著进展。ML可协助识别VTE的风险因素,建立针对性的风险预测模型。通过对多模态数据的整合,ML可辅助医生快速准确地进行VTE诊断和严重程度评价。在VTE治疗领域,ML可协助制定抗凝药物、剂量和疗程等临床决策,同时预测药物相关不良反应尤其是出血风险。另外,ML也可辅助新药的研发,通过探讨VTE的发病机制从而寻找干预靶点。

关键词：静脉血栓栓塞人工智能机器学习

Microstructure evolution and mechanical behavior of Ni-rich Ni-Mn-Ga alloys under compressive and tensile stresses

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Journal of Materials Science & Technology 2022年第2期97卷 113-122页

作者： Yue Wang Siyuan Yang Ting Zhou Long Hou Lansong Ba Yves Fautrelle Zhongming Ren Yanyan Zhu Zongbin Li xi Li state Key laboratory of Advanced Special Steels Shanghai UniversityShanghai 200072China Shanghai Key Lab of Advanced High-temperature Materials and Precision Forming Shanghai Jiao Tong UniversityShanghai 200240China EPM-Madylam ENSHMG BP 38402St Martin d’Heres CedexFrance School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Key laboratory for Anisotropy and Texture of Materials Northeastern UniversityShenyang 110819China

The microstructure evolution and mechanical behavior in directionally solidified Ni-rich Ni-Mn-Ga alloys with nominal compositions of Ni_(58)Mn_(25)Ga_(17) and Ni_(60)Mn_(25)Ga_(15) under compressive and tensile stresses have been *** composition distribution shows the element Ni segregates in gamma phase,while elements Mn and Ga segregate in martensite ***,the microstructure orientation examined by electron backscatter diffraction(EBSD)indicates that beta phase has a preferred growth orientation of(001)_(A) in Ni_(58)Mn_(25)Ga_(17) alloys,while gamma phase has a preferred growth orientation of(001)_(γ) in Ni_(60)Mn_(25)Ga_(15) *** fracture morphology suggests that the existence of ductile y phase can reduce the crack propagation and promote fracture strain,particularly in the Ni_(60)Mn_(25)Ga_(15) ***,Schmid factor and deformation gradient tensor were calculated to well explain the crystallographic evolution during the detwinning under compressive and tensile *** present findings not only elucidate the mechanism ofγphase on the mechanical behavior of Ni-rich Ni-Mn-Ga alloys,but also shed light on the composition design of high temperature Ni-Mn-Ga shape memory alloys.

关键词： Ni-Mn-Ga Gamma phase Tensile Compressive EBSD

Creep Behavior and Life Assessment of a Novel Heat-Resistant Austenite Steel and Its Weldment

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Acta Metallurgica Sinica(English Letters) 2019年第5期32卷 638-650页

作者： Yu Zhang Hong-Yang Jing Lian-Yong Xu Yong-Dian Han Lei Zhao xi-Shan xie Qiu-Hua Zhu School of Materials Science and Engineering Tianjin University Tianjin Key laboratory of Advanced Joining Technology School of Materials Science and Engineering University of Science and TechnologyBeijing Jiangsu Wujin Stainless Steel Pipe Group Co. Ltd

In the present study, creep activation energy for rupture was obtained as 221-3.8 kJ/mol for 22Cr15Ni3.5 CuNbN due to the precipitation-hardening mechanism. The extrapolation strength of creep rupture time of 10~5 h at 923.K for22 Cr15 Ni3.5 CuNbN is more valid(83.71 MPa) predicted by the Manson-Haferd method, which is superior to other commercial heat-resistant steels. The tensile creep tests ranging from 180 to 240 MPa at 923.K were conducted to investigate creep deformation behavior of welded joint between a novel heat-resistant austenite steel 22Cr15Ni3.5 CuNbN and ERNiCrCoMo-1 weld metal. Apparent stress exponent value of 6.54 was obtained, which indicated that the ratecontrolled creep occurred in weldment during creep. A damage tolerance factor of 6.4 in the weldment illustrates that the microstructural degradation is the dominant creep damaging mechanism in the alloy. Meanwhile, the welded joints perform two types of deformation behavior with the variation in applied stress, which resulted from the different parts that govern the creep processing. Also, the morphology evolution of the fracture surfaces confirms the effects of stress level and stress state.

关键词： Heat-resistant steel weldment Creep deformation Life assessment TTP(time–temperature parametric) method