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Analysis of the Reaction Products of N-Phosphoryl Alanine with Four Nucleoside by HPLC-ESI-MS/MS

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Analysis of the Reaction Products of N-Phosphoryl Alanine wi...

中国化学会第四届有机化学学术会议

作者： CAO, Shu-Xia GUO, Yan-Chun LU, Jian-Sha LIAO, Xin-Cheng ZHAO, Yu-Fen (Key Laboratory of chemical biology and Organic Chemistry, Department of Chemistry, Zhengzhou university, Zhengzhou 4.0052) (Key Laboratory for Bioorganic Phosphorus Chemistry and chemical biology, Ministry of Education, Department of Chemistry, school of Life sciences and engineering, Tsinghua university, Beijing 100084.

＜正＞It has long been a major question in origin of life studies that which came first, nucleic acid or protein? Prof. Zhao has found that N-（O,O-diisopropyl） phosphoryl amino acids （DIPP-AA） not only are capable of self-assembly into oligopeptides but also can act as the phosphoryl donor to phosphorylate nucleosides to nucleo-tides and oilgonucleotides. Therefore, the hypothesis was proposed that N-phosphoryl amino acids might be regarded as the common original seed for nucleic acids and prebiotic proteins. In the previous work, it was found

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SYSTEMS biology AND METABOLIC engineering:MICROBIAL STRAIN IMPROVEMENT AND BIOPROCESS OPTIMISATION

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SYSTEMS BIOLOGY AND METABOLIC ENGINEERING:MICROBIAL STRAIN I...

首届国际生物经济高层论坛

作者： ZHAO Xueming~* CHEN Xun CHEN Tao WANG Qingzhao and ZHOU Shiqi Department of Biochemical engineering school of chemical engineering & Technology National engineering Research Center for Fermentation Technology(Tianjin) Tianjin university Tianjin 3.0072 china

＜正＞Systems biology studies biological systems by systematically perturbing them （biologically,genetically,chemically or physically）;monitoring the gene,protein, metabolite and informatical pathway responses;integrating these data;and ultimately, formulating mathematical models that describe the structure of the system and its response to individual *** engineering is the improvement of cellular properties by using modern genetic engineering *** engineering encompasses three important steps:the modification of cellular pathways（synthesis）,the rigorous evaluation of the phenotype of the modified cells（phenotype characterization） and optimization design of further genetic modification（design）.In the procedure,"OME"analyses play great roles in the phenotype *** the environmental conditions have also great effects on the cellular properties,so the changes of the cellular properties under different environmental conditions must be evaluated by the"OME"*** on the"OME"analyses,it is possible to get valuable knowledge that can be used for the development of metabolic engineering strategies,which consequently are used to optimize the *** this paper,we review the recent advances of metabolic engineering based on systems biology.

关键词： Systems biology metabolic engineering genome transcriptome proteome metabolome fluxome bioprocess

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高模量碳纤维表面双金属MOFs结构的构筑

中国有色金属学报 2024年第5期34卷 1636-1651页

作者：李淑君钱鑫张永刚朱雪张振江吴昊男蔡晨阳朱小龙宁波大学材料科学与化学工程学院宁波315211 中国科学院宁波材料技术与工程研究所碳纤维制备技术国家工程实验室宁波315201 宁波市计量测试研究院宁波新材料检验检测中心国家磁性材料产业计量测试中心宁波315048

经高温热处理制备得到的碳纤维具有高惰性表面结构,导致其与基体之间的润湿性较差。为了改善碳纤维与基体间的界面性能,本研究通过采用阴极电沉积法在高模量碳纤维表面原位生长金属有机框架(MOFs)材料,在纤维表面同时引入两种不同金属元... 详细信息

经高温热处理制备得到的碳纤维具有高惰性表面结构,导致其与基体之间的润湿性较差。为了改善碳纤维与基体间的界面性能,本研究通过采用阴极电沉积法在高模量碳纤维表面原位生长金属有机框架(MOFs)材料,在纤维表面同时引入两种不同金属元素,研究双金属MOFs的引入机制、形貌及其对性能的影响。结果表明:双金属MOFs材料呈一定取向的绣球状形貌,经退火后演变成疏松多孔结构,该结构可显著提高高模量碳纤维表面粗糙度及界面黏结性;双金属MOFs的成核与生长取决于金属还原性,还原性越强、MOF生长速率更快,且沉积量更高;双金属MOFs结构的引入使得纤维电阻率下降至0.05×10^(−5)Ω∙cm,导电性能提升,独特的三维多孔结构也赋予高模量碳纤维高温环境下优异的热稳定性。

关键词：碳纤维金属有机框架金属离子导电性表面粗糙镀

Chiral Discrimination of Quinine and Quinidine Based on Notable Room Temperature Phosphorescence Lifetime Differences with γ-Cyclodextrin as Chiral Selector

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Chiral Discrimination of Quinine and Quinidine Based on Nota...

第三十五届国际光谱会议

作者： X.H.Zhang ~1 Y.Wang ~(1*) W.J.Jin~(1,2*) ~1school of Chemistry and chemical engineering,Shanxi {3., Taiyuan 03.006,china ~2College of Chemistry,Beifing Normal {3.,Beifing 100875,china

＜正＞The chiral recognition is of great importance in many fields including chemistry,biology, pharmaceutical,medical and life science etc[1～2].Fluorescence lifetime resolution based on either time-domain or frequency-domain has been demonstrated to be a powerful technique for the analysis of chiral molecules[3..In the present paper,we investigated the room temperature phosphorescence（RTP）of quinine（QN）and quinidine

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微波对菜籽油部份理化卫生指标影响的研究

西南师范大学学报（自然科学版） 2003年第3期28卷 504-506页

作者：冯有胜单振秀重庆工商大学校区综合办公室重庆400033 重庆工商大学环境与生物工程学院重庆400033

对菜籽油在微波处理下的部份理化卫生指标变化进行了研究,结果指出:菜籽油的羰基值、过氧化值、丙二醛、酸值随微波处理时间延长而升高,其质量趋于下降.

关键词：菜籽油理化卫生指标微波处理羰基值过氧化值丙二醛酸值处理时间

Stochastic and upscaled analytical modeling of fines migration in porous media induced by low-salinity water injection

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Applied Mathematics and Mechanics(English Edition) 2020年第3期41卷 491-506页

作者： Yulong YANG Weifeng YUAN Jirui HOU zhenjiang YOU Jun LI Yang LIU Unconventional Petroleum Research Institute China University of PetroleumBeijing 102249China school of chemical engineering The University of QueenslandBrisbane QLD 4072Australia College of Petroleum engineering China University of PetroleumBeijing 102249China

Fines migration induced by injection of low-salinity water(LSW) into porous media can lead to severe pore plugging and consequent permeability reduction. The deepbed filtration(DBF) theory is used to model the aforementioned phenomenon, which allows us to predict the effluent concentration history and the distribution profile of entrapped particles. However, the previous models fail to consider the movement of the waterflood front. In this study, we derive a stochastic model for fines migration during LSW flooding, in which the Rankine-Hugoniot condition is used to calculate the concentration of detached particles behind and ahead of the moving water front. A downscaling procedure is developed to determine the evolution of pore-size distribution from the exact solution of a large-scale equation system. To validate the proposed model,the obtained exact solutions are used to treat the laboratory data of LSW flooding in artificial soil-packed columns. The tuning results show that the proposed model yields a considerably higher value of the coefficient of determination, compared with the previous models, indicating that the new model can successfully capture the effect of the moving water front on fines migration and precisely match the effluent history of the detached particles.

关键词： low-salinity water(LSW)flooding fines migration stochastic model downscaling porous media waterflooding front exact solution

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聚-β-羟基丁酸的微生物降解性研究

天津大学学报（自然科学与工程技术版） 2002年第1期35卷 95-97页

作者：王加宁杨合同马沛生天津大学化工学院天津300072 山东省科学院生物研究所济南250014

利用已知微生物 ,采用平板培养的方法对化学合成的聚 - β-羟基丁酸 (PHB)及生物发酵制备的 PHB进行生物降解性研究 ,测定了土壤中降解化学合成 PHB的微生物群体及种类 .结果表明 ,降解化学合成及生物制备 PHB的微生物主要为假单胞杆菌 ... 详细信息

利用已知微生物 ,采用平板培养的方法对化学合成的聚 - β-羟基丁酸 (PHB)及生物发酵制备的 PHB进行生物降解性研究 ,测定了土壤中降解化学合成 PHB的微生物群体及种类 .结果表明 ,降解化学合成及生物制备 PHB的微生物主要为假单胞杆菌 ,在土壤中的群体较大 ;化学合成的 PHB降解程度强于生物发酵法制备的 PHB.

关键词：生物降解性聚-β-羟基丁酸土壤微生物假单胞杆菌可降解塑料降解程度

Synthesis of bisphosphnates containing 1,2,3.triazoles via click chemistry

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Synthesis of bisphosphnates containing 1,2,3-triazoles via c...

中国化学会第28届学术年会

作者： Xu Li 1 ,Diandian Ke 1 ,Xiaolan Chen 1,Zhibo Qu 1 ,Lingbo Qu 1,2 ,Yufen Zhao 1 1 Department of Chemistry,Zhengzhou university,Key Laboratory of Organic Chemistry and chemical biology,Henan Province,Zhengzhou 4.0001 2 Chemistry and chemical {4. school,Henan university of Technology, Zhengzhou 4.0001

＜正＞Nitrogen-containing bisphosphonic acids and their salts（N-BP）represent an important class of phosphorus compounds possessing a pyrophosphate-like chemical structure that confers a strong affinity for *** N-BP ... 详细信息

关键词： bisphosphonates 1,2,3.Triazole Ultrasound

四氢吡咯里嗪并[2,1-c]喹啉衍生物的合成及其镇痛作用考察

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沈阳药科大学学报 2010年第1期27卷 44-47页

作者：王溪尧任自跃王玉玲宋宏锐辽宁科技学院生物与化学工程系辽宁本溪117022 沈阳药科大学制药工程学院辽宁沈阳110016

目的研究5,6,6a,11b-四氢-7H-吡咯里嗪并[2,1-c]喹啉类化合物的镇痛作用构效关系,寻找具有镇痛活性的新型四氢喹啉类化合物。方法以吡里酮为原料,合成系列化合物。用乙酸致小鼠扭体法测定该类化合物的镇痛活性。结果合成了13.目标化合... 详细信息

目的研究5,6,6a,11b-四氢-7H-吡咯里嗪并[2,1-c]喹啉类化合物的镇痛作用构效关系,寻找具有镇痛活性的新型四氢喹啉类化合物。方法以吡里酮为原料,合成系列化合物。用乙酸致小鼠扭体法测定该类化合物的镇痛活性。结果合成了13.目标化合物,经波谱分析确证其结构。镇痛活性试验表明,所合成的部分化合物具有较明显的镇痛作用。结论该类化合物值得进一步研究。

关键词：化学合成吡咯里嗪并[2,1-c]喹啉镇痛