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Studies on repairing of hemisected thoracic spinal cord of adult rats by using a chitosan tube filled with alginate fibers

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Progress in Natural Science:Materials International 2006年第10期16卷 1051-1055页

作者： LI Xiaoguang, YANG Zhaoyang and YANG Yi ( Beijing center for Neural Regeneration and Repairing, Capital university of Medical Sciences, Beijing 100054, china Department of Bioengineering, Beijing university of Aeronautics and Astronautics, Beijing 100083. china National center of Biomedical analysis, Beijing 100850, china) Beijing center for Neural Regeneration and Repairing Capital University of Medical Sciences Beijing 100054 China Department of Bioengineering Beijing University of Aeronautics and Astronautics Beijing 100083 China National center of Biomedical analysis Beijing 100850 China

A chitosan tube filled with alginate fibers was implanted into the injured spinal cord of a rat for repairing the damaged tissue. Twelve months after the operation, the morphological observation demonstrated that this chitosan tube could induce regeneration of myelinated and non-myelinated axons and blood vessels. The Basso-Beattie-Bresnahan (BBB) behavioral evaluation confirmed that the implants played a key role in the long-term restoration of rats motor functions. It is a promising start in the treatment of the patients with the injury of the spinal cord.

关键词： spinal cord injury regeneration function recovery chitosan alginate behavioral evaluation.

STUDIES ON SOLID STATE REACTIONS OF COORDINATION COMPOUNDS(LXⅡ)Solid state synthesis and crystal structure of the complex ICu_(0.84)Au_(0.16)(PPh_3._2(SC(Ph)NHPh)CIJ·0.5CS_2

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Chinese Chemical Letters 1992年第12期3卷 1027-1028页

作者： Shi An BAO Jian Ping LANG Xin Quan XIN Coordination Chemistry Institute,nanjing university,nanjing 210008Kai Bei YU Chengdu {3. of analysis and Measurement,Academica Sinica,Chengdu 610015

[Cu_(0.84)Au_(0.16)(PPh_3._2(SC(Ph)NHPh)Cl]·0.5CS_2=,Mr=895.79,monoclinic,space group P2_1/a,a=17.23.(3.,b=14.611(2),c=18.000(3. ,β=105.56(2)°,V=43.5(1) ~3. Z=4,D_c=1.3.g/cm^3.,λ(MoK_α)=0.71073.,μ=12.15cm^(-1),F(000)=1855,R=0.052, R_W=0.045 for 3.3. observed reflections with Ⅰ>1.5σ(Ⅰ).The central metal atom has a dis. torted tetrahedral geometry with bond lengths Cu-S=2.3.4(2) (Au-S=2.3.9(4)), Cu-Cl=2.481(3.(Au-Cl=2.474(1))and Cu-P=2.269(2)-2.289(2)(Au-P=2.270(4)-2.279(4)) .

关键词： STUDIES ON SOLID STATE REACTIONS OF COORDINATION COMPOUNDS CS Ph)NHPh)CIJ Au LX PPh3 Solid state synthesis and crystal structure of the complex ICu SC

Main chemical ingredients of the celadon glaze from Qingliangsi kiln and Zhanggongxiang kiln

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Science china(Physics,Mechanics & Astronomy) 2006年第4期49卷 487-495页

作者： ZHAO Weijuan1, LU Xiaoke1, LI Guoxia1, GUO Min1, XIE Jianzhong1, GAO Zhengyao1, SUN Xinmin2, GUO Musen2, CHENG Huansheng3.& ZHANG Bin3.1. Faculty of Physical Engineering, Zhengzhou university, Zhengzhou 450052, china 2. Research Institute of Cultural Relic and Archaeology, Henan Province, Zhengzhou 450004, china 3. Research Institute of {3. Physics, Fudan university, Shanghai 20043., china Faculty of Physical Engineering Zhengzhou University Zhengzhou China Research Institute of Cultural Relic and Archaeology Zhengzhou China Research Institute of modern Physics Fudan University Shanghai China

The proton induced X-ray emission (PIXE) is used to determine the chemical ingredients of seven main elements in the samples of Ru Guan porcelain glazes and Ru Civil porcelain from Qingliangsi kiln in Baofeng County and the samples of celadon glaze from Zhanggongxiang kiln in Ruzhou City. The PIXE data are then analyzed by scatter analysis and fuzzy cluster method for determining their classification and provenance. The results show that there are obvious differences between the ingredients of glaze material of Ru Guan porcelain and Ru Civil porcelain from Qingliangsi kiln, of which the former ingredients are stable and its source is localized, and that the sources and ingredients of the glaze of Ru Guan porcelain and those of celadon glaze from Zhanggongxiang kiln are not wholly the same, of which the latter sources are much scattering.

关键词： Zhanggongxiang kiln, Qingliangsi kiln, the source of raw material, the proton induced X-ray emission.

fMRI time series analysis based on stationary wavelet and spectrum analysis

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Progress in Natural Science:Materials International 2006年第11期16卷 1171-1176页

作者： ZHI Lianhe~ 1,2,3., ZHAO Xia~4, SHAN Baoci~1**, PENG Silong~5, YAN Qiang~1, YUAN Xiuli~1 and TANG Xiaowei~ 1,6 (1. Key Laboratory of Nuclear analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, china 2. Graduate School of Chinese Academy of Sciences, Beijing 100049, china 3. Department of Physics, Zhoukou Normal {3., Zhoukou 466100, china 4. Research Imaging center, {3. of Texas Health Science center, San Antonio, Texas 78229, USA 5. National ASIC Design and Engineering center, Institute of Automation, Chinese Academy of Sciences, Beijing 100049, china 6. Department of Physics, Zhejiang {3., Hangzhou 3.0027, china) Key Laboratory of Nuclear analysis Techniques Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Graduate School of Chinese Academy of Sciences Beijing 100049 China Department of Physics Zhoukou Normal University Zhoukou 466100 China Research Imaging center University of Texas Health Science Center San Antonio TX 78229 United States National ASIC Design and Engineering center Institute of Automation Chinese Academy of Sciences Beijing 100049 China Department of Physics Zhejiang University Hangzhou 310027 China

The low signal to noise ratio (SNR) of functional MRI (fMRI) prefers more sensitive data analysis methods. Based on stationary wavelet transform and spectrum analysis, a new method with high detective sensitivity was developed for analyzing fMRI time series, which does not require any prior assumption of the characteristics of noises. In the proposed method, every component of fMRI time series in the different time-frequency scales of stationary wavelet transform was discerned by the spectrum analysis, then the components from noises were removed using the stationary wavelet transform, finally the components of real brain activation were detected by cross-correlation analysis. The results obtained from both simulated and in vivo visual experiments illustrated that the proposed method has much higher sensitivity than the traditional cross-correlation method.

关键词： fMRI stationary wavelet transform spectrum analysis data analysis.

Modifying NaY Zeolite with Metal Oxide by Microwave Irradiation:Influence on the Adsorption and Decomposition of N-nitrosamines

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Chinese Chemical Letters 2000年第7期11卷 649-652页

作者： Li Li MA Bin SHEN Jian Hua ZHU Jia Rong XIA Qin Hua XU(Chemistry Department, nanjing university, nanjing 2.0093. Chemistry Department Nanjing University Nanjing 210093 China

Coating *** ZrO2 on zeolite NaY accelerated decomposition of N-nitrosodimethylamine and N-nitrosopyrrolidine, resulting from variation of the surface state such as generation of basic sites.

关键词： zeolite NaY MgO ZrO2 N-nitrosamines cigarette smoke

Synthesis of a new salt containing polyoxometallate anion and M-Cu-S cluster cation [MS_4Cu_4(γ-MePy)_8][M_6O_19] (M = Mo,W).Crystal structure of [WS_4Cu_4(γ-MePy)_8][W_6O_19]

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Chinese Journal of Chemistry 1995年第1期13卷 40-46页

作者： POPE, Michael T. Department of Chemistry, Georgetown university, Washington DC S0057, U.S.A.LANG, Jian-PingDepartment of Chemistry, Suzhou university, Suzhou, Jiangsu 215006, chinaXIN, Xin-Quan Coordination Chemistry Institute,{3., nanjing, Jiangsu S1000S, chinaYU, Kai-BeiChengdu center of analysis and Measurement, Chinese Academy of Sciences, Chengdu, Sichuan 610041, china Department of Chemistry Georgetown University Washington DC 20057 U.S.A. Department of Chemistry Suzhou University Suzhou Jiangsu 215006 China Coordination Chemistry Institute Nanjing University Nanjing Jiangsu 210008 China Chengdu center of analysis and Measurement Chinese Academy of Sciences Chengdu Sichuan 610041 China

Reactions of (NH4)2MS4, AgBr and CuBr in r-methylpyridine produced one new compound, [MS4Cu4(r-MePy)8]M6O19] (1, M = W; 2, M = Mo), of which 1 was characterized by single crystal X-ray analysis. The crystal data: orthorhombic, Pbcn, a = 15.43.(4),b= 16.73.(2), c = 28.657(7) A, V = 7400.8(8) A3. Z = 4, R = 0.072 for 3.21 independent data. The compound is the first example which contains both polyoxotnngstate anion and heteropolynuclear cluster cation. In the structure of the cation four edges of the tetrahedral WS42- core are coordinated by four copper atoms, giving a WS4Cu4 aggregate of approximate D2h symmetry. The differences between the reaction of Cu+ with MS42- and that of Ag+ with MS42- in pyridine and its derivatives are discussed.

关键词： Mo(W)-Cu-S cluster cation polyoxometallate anion crystal structure.

Research on the reconstruction method of porous media using multiple-point geostatistics

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Science china(Physics,Mechanics & Astronomy) 2010年第9期53卷 122-134页

作者： ZHANG Ting 1,2,3. LI DaoLun 1,2 , LU DeTang 1,2 & YANG JiaQing 1,2 1 Department of modern Mechanics, university of Science and Technology of china, Hefei 23.027, china 2 Research center of Oil and Natural Gas, university of Science and Technology of china, Hefei 23.027, china 3.The 28th Research Institute, china Electronics Technology Group Corporation, nanjing, 210007, china Department of modern Mechanics University of Science and Technology of China Hefei China Research center of Oil and Natural Gas University of Science and Technology of China Hefei China The 28th Research Institute China Electronics Technology Group Corporation Nanjing China

The pore structural characteristics have been the key to the studies on the mechanisms of fluids flow in porous media. With the development of experimental technology, the modern high-resolution equipments are capable of capturing pore structure images with a resolution of microns. But so far only 3. volume data of millimeter-scale rock samples can be obtained losslessly. It is necessary to explore the way of virtually reconstructing larger volume digital samples of porous media with the representative structural characteristics of the pore space. This paper proposes a reconstruction method of porous media using the structural characteristics captured by the data templates of multiple-point geostatistics. In this method, the probability of each structural characteristic of a pore space is acquired first, and then these characteristics are reproduced according to the probabilities to present the real structural characteristics in the reconstructed images. Our experimental results have shown that: (i) the deviation of LBM computed permeability respectively on the virtually reconstructed sandstone and the original sample is less than 1.2%; (ii) the reconstructed sandstone and the original sample have similar structural characteristics demonstrated by the variogram curves.

关键词： porous media reconstruction multiple-point geostatistics pore space training image variogram data template

Expression of Basic Fibroblast Growth Factor Results in the Decrease of Myostatin mRNA in Murine C2C12 Myoblasts

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Acta Biochimica et Biophysica Sinica 2006年第10期38卷 697-703页

作者： Hua-Zhong LIU~(1,2) Qing LI~1 Xing-Yuan YANG~1 Lin LIU~1 Lei LIU~1 Xiao-Rong AN~1* Yong-Fu CHEN~1 1 State Key Laboratory for Agrobiotechnology,College of Biological Science,china Agricultural university,Beijing 100094,china 2 {3. Biochemistry center,Guangdong Ocean university,Zhanjiang 524088,china State Key Laboratory for Agrobiotechnology College of Biological Science China Agricultural UniversityBeijing 100094 China modern Biochemistry center Guangdong Ocean UniversityZhanjiang 524088 China

During the development and regeneration of skeletal muscle,many growth factors,such asbasic fibroblast growth factor (bFGF,FGF-2) and myostatin,have been shown to play regulating *** contributes to promote proliferation and to inhibit differentiation of skeletal muscle,whereas myostatinplays a series of contrasting *** order to elucidate whether the expression of bFGF has any relationshipwith the expression of myostatin in skeletal muscle cells,we constructed a eukaryotic expression vector forthe expression of exogenous bFGF in murine C2C12 *** RT-PCR assays indicated thatwith the increase of the expression of exogenous bFGF gene,the expression of endogenous myostatin genewas suppressed at mRNA level and protein level.

关键词： basic fibroblast growth factor myostatin murine C2C12 myoblast real time RT-PCR

Real-time detection of α1A-AR movement stimulated by phenylephrine in single living cells

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Acta Pharmacologica Sinica 2007年第6期28卷 796-802页

作者： Ning XU~(2,5),Zhang-yi LIANG~(3.5),Ming XU~2,Ying-hua GUAN~3.Qi-hua HE~4,Qi-de HAN~2,Xin-sheng ZHAO~(3.6),You-yi ZHANG~(2,6)~2 Institute of Vascular Medicine,Peking university Third Hospital,and Key Laboratory of Molecular Cardiovascular Sciences,Ministry ofEducation,Beijing 100083.china ~3.Beijing National Laboratory for Molecular Sciences,State Key Laboratory for Structural Chemistry ofUnstable and Stable Species,and Department of Chemical Biology,College of Chemistry and Molecular Engineering,Peking university,Beijing 100871,china ~4 center of Medical analysis,Peking university,Health Science center,Beijing 100083.china Institute of Vascular Medicine Peking University Third Hospital and Key Laboratory of Molecular Cardiovascular Sciences Ministry of Education Beijing China Beijing National Laboratory for Molecular Sciences State Key Laboratory for Structural Chemistry of Unstable and Stable Species Department of Chemical Biology College of Chemistry and Molecular Engineering Peking University Beijing China center of Medical analysis Peking University Health Science Center Beijing China

Aim:To investigate the movement of α1A-adrenergic receptors(α1A-AR) stimu-lated by agonist,phenylephrine （PE）,and the dynamics of receptor movement inreal time in single living cells with millisecond ***:We labeledα1A-AR using the monoclonal,anti-FLAG （a kind of tag） antibody and Cy3.conju-gated goat anti-mouse IgG and recorded the trajectory of their transport processin living HEK293. cells stimulated by agonist,PE,and then analyzed their dy-namic ***:The specific detection of α1A-AR on the surface ofliving HEK293.-α1Acells was achieved.α1A-AR internalize under the stimulationof *** the cells were stimulated with PE for 20 min,apparent colocalizationwas found between α1A-AR and *** 40 min stimulation of PE,trajecto-ries of approximate linear motion in HEK293.-α1Acells were recorded,and theirvelocity was ***:The specific labeling method on the livingcell surface provides a convenient means of real-time detection of the behavior ofsurface *** this method we were able to specifically detect α1A-AR andrecord the behavior of individual particles of receptors with 50 ms exposure time inreal time in single living cells.

关键词： adrenergic receptor trajectory living cell