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Comparison of Preliminary Clinical Efficacy for Two Cervical Preparations for Early Second-trimester Pregnancy Termination at 12-17 Weeks Gestation

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Journal of Reproduction and Contraception 2011年第2期22卷 83-88页

作者： Yu-xia WANG Rong ZENG Mi-jiao HUANG Wei-jie ZHU Mei TU Department of Obstetrics and Gynecology the First Clinical College Jinan University Guangzhou 510630 China Department of Material Science and engineering Jinan University Guangzhou 510632 China Department of Obstetrics and Gynecology Dongpu Hospital the First Clinical College Jinan University Guangzhou 530666 China institute of Reproductive Immunology Jinan University Guangzhou 510632 China

Objective To compare clinical efficacy for two cervical preparations for early secondtrimester pregnancy termination at 12-17 weeks gestation. Methods Seventy healthy women aged 18-4. years requesting legal termination of pregnancy at 12-17 weeks of gestation were equally randomized into two groups. Two cervical preparations, the Dilapan-STM combined with mifepristone and misoprostol （DMM） method, and the mifepristone combined with misoprostol （MM） method, were used to end early second-trimester pregnancy for group DMM and group MM, respectively. Clinical outcomes and complications for these two methods were compared. Results No differences were found on rates of successful abortion within 4. h and blood loss after abortion at 2 h between the two groups （P〉0.05）. DMM group had significant shorter induction-to-abortion interval and hospital stay compared with group MM （P〈0.01）. In both DMM and MM groups, side effects including nausea/vomiting, diarrhea, chills and rigors, and fever occurred, and incidences of these side effects were no difference （P〉0.05）. Conclusion DMM method would have similar clinical efficacies with MM method for early second-trimester pregnancy termination. Besides,DMM method has shorter induction-to-abortion interval and hospital stay, which benefits its clinical application.

关键词： cervical preparation Dilapan-dilator second-trimester pregnancy

PREPARATION AND SURFACE CHARACTERIZATION OF TiO2 THIN FILMS ON GLASS BY MAGNETRON SPUTTERING METHOD

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Acta Metallurgica Sinica(English Letters) 2002年第2期15卷 207-209页

作者： L.S.Yin1,3), H. Shen2) and J.X. Zhang3) 1)College of Information engineering, Central South university, Changsha 4.0075, China 2)guangzhou institute of Energy Conversion, CAS, guangzhou 510070, China 3)Department of Physics, Zhongshan university, Guang Coll. of Info. Eng. Central South Univ. Changsha 410075 China

Ti thin films were firstly deposited on glass substrates by magnetron sputtering method, then sintered the Ti thin films in air atmosphere and finally TiO2 transparence thin films on glass substrates were obtained. The structure and surface morphologies of the thin films were characterized by X-ray diffraction and SEM. The growth process of the thin films has been observed. The annealing time and annealing temperatures have an affect on the growth of the films.

关键词： TiO2. thin film. magnetron sputtering

Parameter identification theory of a complex model based on global optimization method

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Science China(Physics,Mechanics & Astronomy) 2008年第11期51卷 1722-1732页

作者： QU jie1, jiN QuanLin2 & XU BingYe3 1 College of Automotive engineering, South China university of Technology, {4. 51064., China 2 Beijing Research institute of Mechanical and Electrical Technology, Beijing 100083, China 3 Department of engineering Mechanics, Tsinghua university, Beijing 100084. China College of Automotive engineering South China University of Technology Guangzhou China Beijing Research institute of Mechanical and Electrical Technology Beijing China Department of engineering Mechanics Tsinghua University Beijing China

With the development of computer technology and numerical simulation technology, computer aided engineering (CAE) technology has been widely applied to many fields. One of the main obstacles, which hinder the further application of CAE technology, is how to successfully identify the parameters of the selected model. An elementary framework for parameter identification of a complex model is provided in this paper. The framework includes the construction of objective function, the design of the optimization method and the evaluation of the identified results, etc. The parameter identification process is described in this framework, taking the parameter identification of the superplastic constitutive model considering grain growth for Ti-6Al-4. at 927°C as an example. The objective function is the weighted quadratic sums of the difference between the experimental and computational data for the stress-strain relationship and the grain growth relationship; the designed optimization method is a hybrid global optimization method, which is based on the feature of the objective function and incorporates the strengths of genetic algorithm (GA), the Levenberg-Marquardt algorithm and the augmented Gauss-Newton algorithm. The reliability evaluation of parameter identification result is made through the comparison between the calculated and experimental results and between the theoretical values of the parameters and the identified ones.

关键词： constitutive model parameter identification theory inverse analysis global optimization

STUDY ON PREPARATION OF ORGANIC/INORGANIC HYBRID BIOMATERIALS THROUGH SOL-GEL PROCESS

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Chinese Journal of biomedical engineering(English Edition) 1997年第4期6卷 257-276页

作者： Zou Han Chen Hongmei (institute of biomedical engineering,ji{4. university, Guangzhoh, {4.,China)

-A Sol-gel process has been utilized to produce hybrid materials by in-corporating polymeric components of PDMS and PHEMA with tetraethoxysilane (TEOS) *** experiments were carried out to study the erfects of catalyst, H2O, and TEOS content on the structure-property behavior of TEOS-PDME materials. Results from dynamic mechanical and SEM studies indicated good dispersion of the PDMS component within the three dimensional network and no signs of phase ceparation. As to TEOS-KH570-HEMA system, all the samples made were ransparent and flexible. The water content was about 30%, stress at break varie from 0.4.to 1.1 MPa with dirferent HEMA content. Animal tests showed no rcaction to living body and the materials made by this way displayed good biocompatibility.

关键词： Sol-gel process hybrid material

Deep learning-based lung sound analysis for intelligent stethoscope

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Military Medical Research 2024年第4期11卷 567-588页

作者： Dong-Min Huang jia Huang Kun Qiao nan-Shan Zhong Hong-Zhou Lu Wen-jin Wang Department of biomedical engineering Southern University of Science and TechnologyShenzhen 518055GuangdongChina The Third People’s Hospital of Shenzhen Shenzhen 518112GuangdongChina guangzhou institute of Respiratory Health China State Key Laboratory of Respiratory DiseaseNational Clinical Research Center for Respiratory Diseasethe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120China

Auscultation is crucial for the diagnosis of respiratory system ***,traditional stethoscopes have inherent limitations,such as inter-listener variability and subjectivity,and they cannot record respiratory sounds for offline/retrospective diagnosis or remote prescriptions in *** emergence of digital stethoscopes has overcome these limitations by allowing physicians to store and share respiratory sounds for consultation and *** this basis,machine learning,particularly deep learning,enables the fully-automatic analysis of lung sounds that may pave the way for intelligent *** review thus aims to provide a comprehensive overview of deep learning algorithms used for lung sound analysis to emphasize the significance of artificial intelligence(AI)in this *** focus on each component of deep learning-based lung sound analysis systems,including the task categories,public datasets,denoising methods,and,most importantly,existing deep learning methods,i.e.,the state-of-the-art approaches to convert lung sounds into two-dimensional(2D)spectrograms and use convolutional neural networks for the end-to-end recognition of respiratory diseases or abnormal lung ***,this review highlights current challenges in this field,including the variety of devices,noise sensitivity,and poor interpretability of deep *** address the poor reproducibility and variety of deep learning in this field,this review also provides a scalable and flexible open-source framework that aims to standardize the algorithmic workflow and provide a solid basis for replication and future extension:https://***/contactless-healthcare/Deep-Learning-for-Lung-Sound-Analysis.

关键词： Deep learning Lung sound analysis Respiratory sounds

Cr^(3+) activated Na_(3)RESi_(3)O_(9)(RE=Y,Lu,Sc) silicate broadband near-infrared phosphors for luminescence towards NIR-Ⅱ region via a multi-site occupancy strategy

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Journal of Rare Earths 2024年第8期42卷 1447-1457,I0002页

作者： jiantong Wang Changshuai Gong Sihan Yang Qi Zhu Xuejiao Wang ji-Guang Li College of Chemistry and Materials engineering Bohai UniversityJinzhou121007China Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) School of Materials Science and EngineeringNortheastern UniversityShenyang110819China Research Center for Electronic and Optical Materials National Institute for Materials ScienceTsukubaIbaraki 305-0044Japan

Phosphor-converted near-infrared light-emitting diodes(NIR pc-LEDs) are finding applications in various fields including food quality analysis,biomedical imaging,night vision,and *** crucial factor in the development of NIR pc-LEDs devices lies in the advancement of high-performance broadband NIR phosphors,In this work,novel Cr^(3+)-activated silicate phosphors NaRESi_(3)O_(9)(RE=Y,Lu,Sc) are *** silicate has a special 3D network structure in which RE has four different sites,forming four octahedrons and providing suitable occupation sites for Cr^(3+).The phosphors demonstrate a wide emission spectrum ranging from 750 to 14.0 nm when excited by light at 4.8 *** full width at half maximum(FWHM),which benefits from the presence of Cr^(3+)ions occupying multiple sites,is measured to be 203 ***,the strongest emission peak is observed at a longer wavelength of 984.nm compared to most other systems activated by Cr^(3+).The Na_(3)ScSi_(3)O_(9) lattice provides a weak crystal field(Dq/B=1.97) and weak phonon-photon coupling for Cr^(3+),and the integrated emission intensity of Na_(3)ScSi_(3)O_(9):0,03Cr^(3+)is 4.66 times stronger than that of Na_(3)YSi_(3)O_(9):0.03Cr^(3+).

关键词： Rare earths Broadband near-infrared Silicate Photoluminescence Cr^(3+)

State space approach for joint estimation of activity and attenuation map from PET emission sinograms

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Progress in Natural Science:Materials International 2007年第5期17卷 614-617页

作者： Liu Huafeng , You Hongshun and Shi Pengcheng (State Key Laboratory of Modern Optical Instrumentation, Zhejiang university, Hangzhou 310027, China College of biomedical engineering, Southern Medical university, {4. 510015, China) State Key Laboratory of Modern Optical Instrumentation Zhejiang University Hangzhou 310027 China College of biomedical engineering Southern Medical University Guangzhou 510015 China

Quantitative estimation of radioactivity map has important clinical implications for better diagnosis and understanding of cancers. Although attenuation map and activity map are usually treated sequentially, they can obviously benefit a great deal when the transmission data is missing. In this paper, we propose a novel scheme of simultaneously solving for attenuation map and activity distribution from emission sinograms. Our strategy combines the measurement model of PET, and the attenuation parameters are treated as random variables with known prior statistics. After the conversion to state space representation, the extended Kalman filtering procedures are adopted to linearize the equations and to provide the joint estimates in an approximate optimal sense. Experiments have been performed on both synthetic data to illustrate its abilities and benefits.

关键词： positron emission tomography attenuation correction state space methods.

RESEARCH ON COUPLED RELATIONSHIP BETWEEN HYDRATION NUMBER WITH RAMAN SPECTRUM

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化工学报 2003年第Z1期54卷 41-46页

作者： LEI Huaiyan~(1,2), LIU Zhihong~3, FAN Shuanshi~2, XU Maoquan~1 and GUAN Baocong~1 (~1 institute of Oceanography and Environment, Xiamen university ~2 guangzhou institute of Energy Conversion, CAS ~3 institute of Chemical engineering, Xiamen university) institute of Oceanography and Environment Xiamen University guangzhou institute of Energy Conversion CAS institute of Chemical engineering Xiamen University guangzhou institute of Energy Conversion CAS institute of Oceanography and Environment Xiamen University

As we know, there are three structures-sⅠ, sⅡ, and sH, with hydrocarbonate gas *** of those special structures characteristics and potentail large fossil energy resource, gas hydrate play an important role in natural carbonate cycle system. In this paper, CH4. CO2, C3H8, and CH4.+CO2 system have been experimental performed in order to model hydrate formation and discomposition and to obtain hydrate stability conditions of tempreature and pressure. The results from laboratory using Raman spectra show that Raman spectrascopy is a effective tool to identify hydrate structure. Raman spectra of clathrate hydrate guest molecules are presented for two structure (sⅠ and sⅡ) in the following systems: CH4. CO2, C3 H8. Relatively occupancy of CH4.in the large and small cavities of sⅠ were determined by deconvoluting the v1 symmetric bands, resulting in hydration numbers of 6.04.0.03. The freqyuency of the v1 bands for CH4.in structures Ⅰ and Ⅱ differ statistically. The large cavities were measured to be almost fully occupied by CH4.and CO2, whereas only a small fraction of the small cavities are occupied by CH4. No CO2 was found in the small cavities.

关键词： CH4. CO2, C3H8 Clathrate Hydrate, Raman Spectrum, Hydration Number

A novel model-free approach for reconstruction of time-delayed gene regulatory networks

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中国科学：生命科学英文版 2006年第2期49卷 190-200页

作者： jiANG Wei1,2, LI Xia1,2,3,4. GUO Zheng1,2,3, LI Chuanxing1, WANG Lihong1 & RAO Shaoqi1,5 1. Department of Bioinformatics, Harbin Medical university, Harbin 150086, China 2. Department of Computer Science, Harbin institute of Technology, Harbin 150080, China 3. School of Life Science and Technology, Tongji university, Shanghai 200092, China 4. biomedical {4. institute, Capital university of Medical Sciences, Beijing 100054. China 5. Departments of Cardiovascular Medicine and Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 4.195, USA Department of Bioinformatics Harbin Medical University Harbin China Department of Computer Science Harbin Institute of Technology Harbin China School of Life Science and Technology Tongji University Shanghai China Departments of Cardiovascular Medicine and Molecular Cardiology Cleveland Clinic Foundation Cleveland USA

Reconstruction of genetic networks is one of the key scientific challenges in functional genomics. This paper describes a novel approach for addressing the regulatory dependencies be-tween genes whose activities can be delayed by multiple units of time. The aim of the proposed ap-proach termed TdGRN (time-delayed gene regulatory networking) is to reversely engineer the dy-namic mechanisms of gene regulations, which is realized by identifying the time-delayed gene regu-lations through supervised decision-tree analysis of the newly designed time-delayed gene expres-sion matrix, derived from the original time-series microarray data. A permutation technique is used to determine the statistical classification threshold of a tree, from which a gene regulatory rule(s) is ex-tracted. The proposed TdGRN is a model-free approach that attempts to learn the underlying regula-tory rules without relying on any model assumptions. Compared with model-based approaches, it has several significant advantages: it requires neither any arbitrary threshold for discretization of gene transcriptional values nor the definition of the number of regulators (k). We have applied this novel method to the publicly available data for budding yeast cell cycling. The numerical results demonstrate that most of the identified time-delayed gene regulations have current biological knowledge supports.

关键词： gene regulatory networks, time delayed, decision tree.