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Discovery of immune related factors in Fenneropenaeus chinensis by annotation of ESTs

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Progress in Natural Science:Materials International 2004年第1期14卷 48-55页

作者： SHEN Yaoqing 1,2 , XIANG Jianhai 1*, WANG Bing 1,2 , LI Fuhua 1 and TONG Wei 3(1. Experimental Marine Biology Laboratory, institute of Oceanology, chinese academy of sciences, Qingdao 266071,china 2. Graduate School of the chinese academy of sciences, beijing 100039, china 3. genomics & Bioinformatics institute, chinese academy of sciences, beijing 101300, china) chinese Acad Sci Inst Oceanol Expt Marine Biol Lab Qingdao 266071 Peoples R China chinese Acad Sci Grad Sch Beijing 100039 Peoples R China chinese Acad Sci Geonom & Bioinformat Inst Beijing 101300 Peoples R China

A total of 10446 expressed sequence tags (ESTs) are obtained by a large scale sequencing of a cDNA library from cephalothorax of adult Fenneropenaeus chinensis . An EST analysis platform was built up based on local computers and bioinformatic techniques were used to annotate these ESTs in order to promptly find possible functional genes, especially for immune related factors. About 4% of the ESTs show similarity to the coding sequences of such factors, including lectin, serine protease, serpin, lysozyme, etc. These ESTs provide a partial profile of the immune system in F. chinensis and useful information for further study on these genes.

关键词： Fenneropenaeus chinensis bioinformatics ESTs immune factors

2023 Guideline for the management of hypertension in the elderly population in china

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Journal of Geriatric Cardiology 2024年第6期21卷 589-630页

作者： Hypertension Branch of chinese Geriatrics Society,beijing Hypertension Association,National Clinical Research Center of the Geriatric Diseases Qi HUA Li FAN Zeng-Wu WANG Jing LI 不详 Xuanwu Hospital Capital Medical UniversityBeijingChina chinese PLA General Hospital BeijingChina Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Preamble Hypertension is one of the most common chronic diseases and the primary risk factor for stroke,myocardial infarction and even cardiovascular *** than half of the elderly population has high blood *** people are a unique group,and strategies for the prevention,diagnosis,evaluation,and treatment of hypertension in elderly individuals differ significantly from those in the general population.

关键词： hypertension prevention diagnosis

Overview of HBV whole genome data in public repositories and the chinese HBV reference sequences

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Progress in Natural Science:Materials International 2008年第1期18卷 13-20页

作者： Guanghua Wu a,b, Huiguo Ding c, Changqing Zeng b,* a Graduate School of chinese academy of sciences, beijing 100049, china b beijing institute of genomics, chinese academy of sciences, beijing 101300, china c beijing Youan Hospital, Capital Medical University, beijing 100069, china Graduate School of chinese academy of sciences Beijing 100049 China beijing institute of genomics Chinese Academy of Sciences Beijing 101300 China beijing Youan Hospital Capital Medical University Beijing 100069 China

The number of Hepatitis B virus (HBV) whole genomic sequences in public nucleotide databases (GenBank, EMBL, and DDBJ) had reached 866 by January 1, 2007. Coming from 46 countries and regions, these sequences were categorized as eight genotypes (A–H). With the statistical and phylogenetic analysis on all available complete genomic data of HBV, we here present an overview of HBV sequences in public databases. From all registered 229 HBV genomes in chinese regions as well as 59 sequencing data from our research group, we report the establishment of reference sequences of HBV strains prevailing in china. These analyses provide clues for the effects of HBV genotypes in host clinical progressions, geographic distribution of the infection, and the viral evolutionary history. Moreover, the viral sequence reference would be helpful in the identiffcation of various HBV mutations. Based on the analysis of various public databases, we suggest that the chinese HBV database with the clinical information should be constructed.

关键词： Public databases HBV genomic sequences Genotype Subtype chinese reference sequences

MODELLING AND NUMERICAL SOLUTIONS OF A GAUGE PERIODIC TIME DEPENDENT GINZBURG-LANDAU MODEL FOR TYPE-Ⅱ SUPERCONDUCTORS

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Journal of Computational Mathematics 1997年第4期15卷 365-384页

作者： Zhi-ming Chen (institute of Mathematics, chinese academy of sciences, beijing, china) 中科院数学所北京

In this paper we seek the solutions of the time dependent Ginzburg-Landau model for type-Ⅱ superconductors such that the associated physical observables are spatially periodic with respect to some lattice whose basic lattice cell is not necessarily rectangular. After appropriately foring the gange, the model can be formulated as a system of nonlinear parabolic partial differential equations with quasi-periodic boundary conditions. We first give some results concerning the existence, uniqueness and regularity of solutions and then we propose a semiimplicit finite element scheme solving the system of nonlinear partial dmerential equations and show the optimal error estimates both in the L2 and energy *** also report on some numerical results at the end of the paper.

关键词： Math QT MODELLING AND NUMERICAL SOLUTIONS OF A GAUGE PERIODIC TIME DEPENDENT GINZBURG-LANDAU MODEL FOR TYPE SUPERCONDUCTORS

Finding Signals for Plant Promoters

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genomics, Proteomics & Bioinformatics 2003年第1期1卷 68-73页

作者： Weimou Zhenginstitute of Theoretical Physics, chinese academy of sciences, beijing 100080, china beijing genomicsinstitute, chinese academy of sciences, beijing 101300, china institute of Theoretical Physics Chinese Academy of Sciences Beijing 100080 China beijing genomics institute Chinese Academy of Sciences Beijing 101300 China

The strongest signal of plant promoter is searched with the model of single motif with two types. It turns out that the dominant type is the TATA-box. The other type may be called TATA-less signal, and may be used in gene finders for promoter recognition. While the TATA signals are very close for the monocot and the dicot, their TATA-less signals are significantly different. A general and flexible multi-motif model is also proposed for promoter analysis based on dynamic programming. By extending the Gibbs sampler to the dynamic programming and introducing temperature, an efficient algorithm is developed for searching signals in plant promoters.

关键词： for on is as et Pro Finding Signals for Plant Promoters been of into

What Are You Going to Conquer with the Spear?

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genomics,Proteomics & Bioinformatics 2005年第1期 9-10页

作者： Jun Yu beijing genomics institute, chinese academy of sciences, beijing 101300, china. beijing genomics institute Chinese Academy of Sciences Beijing 101300 China

Almost everyone in china knows this story, even elementary school pupils: Once upon a time, there was a weapon salesman claiming with confidence to one crowd that all his spears were capable of piercing every shield that existed in the world, then he turned around and told the other crowd mysteriously that all his shields were not penetrable. A bystander who heard both claims asked him, How about stabbing your shields with your spears? It was indeed an unexpected question that made the eloquent salesman mute right on the spot. Since then, the chinese people have called contradiction as mao-dun, which literally means the spear (pronounced as mao) and shield (pronounced as dun).

关键词： What Are You Going to Conquer with the Spear Nature gene

SYNTHESIS AND CHARACTERIZATION OF NEW STABILIZERS WITH OPTIMAL MOLECULAR WEIGHT

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chinese Journal of Polymer Science 2001年第4期19卷 341-350页

作者： Jiang-qing Pan institute of Chemistry chinese academy of sciences, beijing 100080 china chinese Acad Sci Inst Chem Beijing 100080 Peoples R China

Over 2 x 10(8) tons of polymers are produced every year, and a large portion of polymers faces the degradation problem. There are many effective methods to protect polymers against degradation and the addition of stabilizers to polymer remains the most convenient and effective way of enhancing polymer life and performance. In this article, a series of effective stabilizers with optimal molecular weight (MW), including common, monomeric and polymeric stabilizers (antioxidant and light stabilizer) were synthesized using isocyanation, controlled isocyanation, hydrosilylation, epoxide addition, macroreaction of stabilizing functional compounds and polymerization of monomeric stabilizers. The structure and performance of these new stabilizers were characterized by using IR, NMR, MS, UV-spectra, XPS and elemental analysis. The current development of stabilizer synthesis was also reviewed.

关键词： preparation of stabilizer antioxidant hindered amine light stabilizer isocyanation hydrosilylation

A NEW STABILIZED FINITE ELEMENT METHOD FOR SOLVING THE ADVECTION-DIFFUSION EQUATIONS

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Journal of Computational Mathematics 2002年第1期20卷 57-64页

作者： Huo-yuan Duan (institute of Mathematics, academy of Mathematics and System sciences, chinese academy of sciences, beijing 100080, china) institute of Mathematics Academy of Mathematics and System Sciences Chinese Academy of Sciences 北京 100080

Focuses on a study on the development of a stabilized finite element method for solving the advection-diffusion equations with a zero Dirichlet boundary condition. Problem formulation; Error analysis.

关键词： advection-diffusion equation stabilized finite element method

ELTA-WAVE IN A SIMPLE 1-D 2 x 2 HYPERBOLIC PROBLEM

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Journal of Computational Mathematics 1996年第4期14卷 311-318页

作者： S.L. Yang(institute of Applied Mathematics, chinese academy of sciences, beijing, china) institute of Applied Mathematics Chinese Academy of Sciences Beijing China

A simple one-dimensional 2 x 2 hyperbolic system is considered in the *** model contains a linear hyperbolic equation, as well as a hyperbolic equation ofwhich the coefficients are about the solution of the linear one. The exact solution ispresented and discussed, then numerical experiments are given by TVD (or MmB)type schemes for Riemann problems. From the results, we know that the solutionsdo have δ-waves for some suitable initial data.

关键词： Zhang Figure DELTA-WAVE IN A SIMPLE 1-D 2 HYPERBOLIC PROBLEM