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Prediction of Tumor Outcome Based on Gene Expression Data

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wuhan university Journal of Natural Sciences 2004年第2期9卷 177-182页

作者： Liu Juan 1,2, Hitoshi Iba 3 1. school of Computer, wuhan university, wuhan 430072, hubei, china 2. State Key Laboratory of Software Engineering, wuhan 430072, hubei, china 3. Department of Frontier Informatics, university of Tokyo, Tokyo 113-8656, Japan school of Computer Wuhan University Wuhan Hubei China State Key Laboratory of Software Engineering Wuhan Hubei China Department of Frontier Informatics University of Tokyo Tokyo Japan

Gene expression microarray data can be used to classify tumor types. We proposed a new procedure to classify human tumor samples based on microarray gene expressions by using a hybrid supervised learning method called MOEA+WV (Multi-Objective Evolutionary Algorithm+Weighted Voting). MOEA is used to search for a relatively few subsets of informative genes from the high-dimensional gene space, and WV is used as a classification tool. This new method has been applied to predicate the subtypes of lymphoma and outcomes of medulloblastoma. The results are relatively accurate and meaningful compared to those from other methods. Key words bioinformatics - tumor classification - Pareto optimization - MOEA CLC number Q 786 - TP 181 Foundation item: Supported by the National Natural Science Foundation of china (60301009), the Foundation of Young Scholars of Ministry of Education of china (150118) and Chenguang Project of wuhan City (211121009).Biography: Liu Juan (1970-), female, Associate Professor, Postdoctoral, research direction: bioinformatics, data mining, machine learning.

关键词： bioinformatics tumor classification Pareto optimization MOEA

A Fast Pseudorandom Number Generator with BLAKE Hash Function

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wuhan university Journal of Natural Sciences 2010年第5期15卷 393-397页

作者： WANG Houzhen1,2,ZHANG Huanguo1,2 1.Key Laboratory of Aerospace Information Security and Trusted Computing of Ministry of Education,wuhan university,wuhan 430072,hubei,china 2.school of Computer,wuhan university,wuhan 430072,hubei,china Key Laboratory of Aerospace Information Security and Trusted Computing of Ministry of Education Wuhan University Wuhan Hubei China school of Computer Wuhan University Wuhan Hubei China

This paper presents a fast pseudorandom generation algorithm,which is based on the BLAKE hash function and can pass the random test of the NIST（National Institute of Standards and Technology） Statistical Test *** theoretical analysis and experimental imitation,our new algorithm is proven to be more secure and efficient than ***,we introduce and discuss the BLAKE in *** security shows that can be utilized to generate pseudorandom bit sequences,which the experimental results show the BLAKE hash function has excellent ***,we believe the BLAKE is one of the most potential candidate algorithms of SHA-3 program.

关键词： cryptography pseudorandom number generator hash function National Institute of Standards and Technology Statistical Test Suite

OPTIMAL PROPORTIONAL REINSURANCE WITH CONSTANT DIVIDEND BARRIER

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Acta Mathematica Scientia 2010年第3期30卷 791-798页

作者：袁海丽胡亦钧 school of mathematics and statistics Wuhan University

In this article, we consider an optimal proportional reinsurance with constant dividend barrier. First, we derive the Hamilton-Jacobi-Bellman equation satisfied by the expected discounted dividend payment, and then get the optimal stochastic control and the optimal constant barrier. Secondly, under the optimal constant dividend barrier strategy, we consider the moments of the discounted dividend payment and their explicit expressions are given. Finally, we discuss the Laplace transform of the time of ruin and its explicit expression is also given.

关键词： Stochastic control constant barrier time of ruin expected discounted dividend payment moments Laplace transform of the time of ruin

Research and Implementation of Unsupervised Clustering-Based Intrusion Detection

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wuhan university Journal of Natural Sciences 2003年第3A期8卷 803-807页

作者： Luo Min, Zhang Huan\|guo, Wang Li\|na school of Computer, wuhan university, wuhan 430072, hubei, china school of Computer Wuhan University Wuhan Hubei China

An unsupervised clustering\|based intrusion detection algorithm is discussed in this paper. The basic idea of the algorithm is to produce the cluster by comparing the distances of unlabeled training data sets. With the classified data instances, anomaly data clusters can be easily identified by normal cluster ratio and the identified cluster can be used in real data detection. The benefit of the algorithm is that it doesn't need labeled training data sets. The experiment concludes that this approach can detect unknown intrusions efficiently in the real network connections via using the data sets of KDD99.

关键词： intrusion detection data mining unsupervised clustering unlabeled data

Minimum Inductance Optimal Design for the Gradient Coil

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wuhan university Journal of Natural Sciences 2002年第3期7卷 302-306页

作者： Chen Yin ping, Zhu Guo qiang school of Electronic Information, wuhan university. wuhan 430072, hubei, china school of Electronic Information Wuhan University Wuhan Hubei China

In MRI (Magnetic Resonance Imaging), a crucial role of gradient coils is to image organism, meanwhile the inductance of the coils determines the speed of imaging. So it is of great importance to optimize designs of the gradient coils. The target field approach is an effective method to design the gradient coils. Having applied this method and performing many numerical tests, we achieved the designs of thex ?,y ?,z ? in which the inductance and resistance of the coils also meet the requirements.

关键词： Key words magnetic resonance imaging linearity target field Fourier transform

Early Age Compressive Strength of Pastes by Electrical Resistivity Method and Maturity Method

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Journal of wuhan university of Technology(Materials Science) 2011年第5期26卷 983-989页

作者：肖莲珍 school of Materials Science and Engineering Wuhan Institute of Technology

The compressive strength development of Portland cement pastes was investigated by the electrical resistivity method and the maturity *** experiments were carried out on the cement pastes with different water-cement ratios at different curing *** results show that the application of the maturity method has limitation to obtain the *** is found that both of the compressive strength and the electrical resistivity follow hyperbolic trend for all the *** hyperbolic equation of each mix is obtained to estimate the ultimate resistivity value which can probably be *** relationship between electrical resistivity and compressive strength of the cement pastes is established based on the test results and interpreted by the empirical Archie equation and a strength-porosity *** relationship between the electrical resistivity after temperature correction and the compressive strength was linear and independent of curing temperature and water-cement ratio.

关键词： electrical resistivity cement hydration compressive strength maturity method

New Wavelet Bases and Isometric Between Symbolic Operators Spaces OpS_(1,δ)~m and Kernel Distributions Spaces

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Acta Mathematica Sinica,English Series 2002年第1期18卷 107-118页

作者： YANG Qi Xiang Department of mathematics. wuhan university. 430072. hubei. P. R. china Department of mathematics Wuhan University Hubei 430072

In the fifties. Calderon established a formal relation between svmbol and kernel distribu-tion, but it is difficult to establish an intrinsic relation. The Calderon-Zygmund (C-Z) school studiedrhe C-Z operators, and Hormander. Kohn and Nirenberg, et al. studied the symbolic operators. Herewe apply a refinement of the Littlewood-Paley (L-P) decomposition, analyse under new wavelet *** characterize both symbolic operators spaces OpS~m and kernel distributions spaces with other spacescomposed of some ahnost diagonal matrices. then get an isometric between OpS~m and kernel distri-bution spaces

关键词： New wavelet bases Psendo-differential operators Kernel-distribution spaces

A theorem of Fong's type for graded algebras

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Science china mathematics 2005年第5期48卷 577-582页

作者： FAN Yun & ZHU Ping school of mathematics and statistics, Central china Normal university, wuhan 430079, china school of Mathematical Science, Nankai university, Tianjin 300071, china school of mathematics and statistics Central China Normal University Wuhan China school of Mathematical Science Nankai University Tianjin China

Let G be a finite p-solvable group and k be an algebraic closed field of characteristic p. It is proved that any projective indecomposable module of a G-graded k-algebra is an induced module of a module of the subalgebra graded by a Hall p′-subgroup. A necessary and sufficient condition for the indecomposability of an induced module from a Hall p′-subgroup is obtained.

关键词： group graded algebra indecomposable induced module primitive idempotent.

ELLIPTIC GRADIENT ESTIMATES FOR DIFFUSION OPERATORS ON COMPLETE RIEMANNIAN MANIFOLDS

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Acta Mathematica Scientia 2010年第5期30卷 1555-1560页

作者：钱斌 school of mathematics and statistics Wuhan University Institut de Math'ematiques de Toulouse Universit'e de Toulouse

In this note, we obtain the elliptic estimate for diffusion operator L = △＋△Ф·△ on complete, noncompact Riemannian manifolds, under the curvature condition CD（K, m）, which generalizes B. L. Kotschwar＇s work [5]. As an application, we get estimate on the heat kernel. The Bernstein-type gradient estimate for SchrSdinger-type gradient is also derived.

关键词： gradient estimate Bakry-Emery curvature diffusion operator