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Journal of wuhan university of Technology(Materials science) 2008年第3期23卷 293-297页

作者：高林 college of life science and Technology Huazhong University of Science and Technology college of Chemistry and Environmental Engineering Yangtze UniversityJingzhou 434023China

Hydroxyapatite （HA） coatings on pyrolytic carbon were produced via electrophoretic deposition （EPD） using glycol and ethanol as dispersion medium respectively. The effect of the solubility of HA in the dispersion medium on crack occurrence and adherence of the coating was investigated by means of scanning electronic microscope （SEM） and atomic absorption spectrometer （AAS）. The results show that the solubility of HA in glycol is higher than that in ethanol. The usage of glycol as a dispersion medium can reduce the possibility of crack formation and enhance the adhesive strength between the coating and the carbon substrate. The green coatings can be sintered under vacuum at 1 000 ℃ whether the coatings are obtained using ethanol or glycol as dispersion medium. No HA decomposition was observed up to 1 000 ℃ by vacuum sintering by X-ray diffraction （XRD） analysis.

关键词： hydroxyapatite electrophoretic deposition coatings dispersion medium glycol

On the Cayley-Bacharach property and the construction of vector bundles

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science china Mathematics 2011年第9期54卷 1891-1898页

作者： SUN Hao 1,2 1 Department of Mathematics and Statistics,huazhong normal university,wuhan 430079,china 2 Department of Mathematics,East china normal university,Shanghai 200241,china 1. Department of Mathematics and Statistics Huazhong Normal University Wuhan 430079 China2. Department of Mathematics East China Normal University Shanghai 200241 China

We study the Cayley-Bacharach property on complex projective smooth varieties of dimension n≥2 for zero dimensional subscheme defined by the zero set of the wedge of r-n + 1 global sections of a rank r≥n vector bund... 详细信息

关键词： Cayley-Bacharach property vector bundle reflexive sheaf k-very ample

Effects of silica nanoparticles on growth and photosynthetic pigment contents of Scenedesmus obliquus

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Journal of Environmental sciences 2010年第1期22卷 155-160页

作者： Chenxi Wei, Yanbo Zhang, Jing Guo, Bing Han, Xu Yang, Junlin Yuan Hubei Key Laboratory of Genetic Regulation and Integrative Biology, college of life sciences, huazhong normal university, wuhan 430079, china. [a] Hubei Key Laboratory of Genetic Regulation Integrative Biology College of Life Sciences Huazhong Normal University Wuhan 430079 China

To assess the aquatic ecosystem safety for silica （SiO2） nanoparticles （NPs）, the growth inhibition and photosynthetic pigment contents of Scenedesmus obliquus in logarithm growth phase exposed to SiO2 NPs and SiO2 bulk particles （BPs） suspensions were measured. SiO2 NPs with 10-20 nm diameters were found to be toxic. The 20% effective concentration （EC20） values for 72 and 96 hr were 388.1 and 216.5 mg/L, respectively. The contents of chlorophyll decreased significantly under moderate and high concentration （50, 100, and 200 mg/L） of SiO2 NPs after 96-hr exposure, but the carotenoids did not. SiO2 BPs were found to be nontoxic up to 200 mg/L. The toxicity of SiO2 NPs probablely due to their sorption to algal cells surface. The results imply that there is potential harm to aquatic environment by using SiO2 NPs, and it should deserve special concern.

关键词： photosynthetic pigment Scenedesmus obliquus silica nanoparticles

A quasi-physical algorithm for solving the linear separation problem in n-dimensional space

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Journal of Central South university of Technology 2001年第4期8卷 272-277页

作者： HUANG Jia yuan (college of Computer science, huazhong university of science and Technology, wuhan 430074, china) 1. college of Computer science Huazhong University of Science and Technology 430074 Wuhan China

A quasi physical algorithm was proposed for solving the linear separation problem of point set in n dimensional *** original idea of the quasi physical algorithm is to find an equivalent physical world for the primitive mathematical problem and to observe the vivid images of the motion of matter in it so as to be inspired to obtain an algorithm for solving the mathematical problem. In this work, the electrostatics with two kinds of matter is found to be the equivalent physical world. As a result,the proposed algorithm is evidently more efficient and robust than the famous LMS algorithm and ETL algorithm. The efficiency of the quasi physical algorithm is about 10-50 times of the LMS algorithm’s for representative instances. A typical Boolean valued instance shows that it is hard for ETL algorithm but very easy for the quasi physical *** this instance, point set A and B is {000, 010, 011, 111} and {001,100}, respectively.

关键词： linear separation problem neural network algorithm quasi-physical method electrostatics

The Study on BCR/ABL Fusion Gene in Adult Acute Lymphoblastic Leukemia

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wuhan university Journal of Natural sciences 2001年第3期6卷 742-746页

作者： Li Hui yu 1,2 ,Zuo Guo Lin 1, ,Zuo Ping 2 1.college of life science, wuhan university,wuhan 430072,china 2.Union Hospital,Tongji Medical college,huazhong university of science and Technology,wuhan 430022,china wuhan university College of Life Science Wuhan China (GRID:grid.49470.3e) (ISNI:***) huazhong university of science and Technology Union Hospital Tongji Medical College Wuhan China (GRID:grid.33199.31) (ISNI:***) wuhan university College of Life Science Wuhan China (GRID:grid.49470.3e) (ISNI:***) huazhong university of science and Technology Union Hospital Tongji Medical College Wuhan China (GRID:grid.33199.31) (ISNI:***)

In order to assess the significance of BCR/ABC fusion gene in adult acute lymphoblastic Leukemia (ALL), 28 patients who were diagnosed as ALL were enrolled to detect BCR/ABC gene using nested-RT-PCR. The results showed that 9 cases (31.25%) were BCR/ABL positive, and expressed P210 subtype. Among them 7 cases were B-ALL, and one was T-ALL. The diagnosis was proved by monoclonal antibodies recognition by indirect immunofluorescence. Adult patients with BCR/ABL positive ALL were significantly older (p0.05). The induction failure rate was high in BCR/ABL positive patients and those who achieved complete remission usually relapsed earlier. In conclusion, adult ALL patients with BCR/ABL-positive have poorer prognosis.

关键词： Key words BCR/ABL gene acute lymphoblastic leukemia nested RT PCR

A New Clustering Algorithm for Categorical Attributes

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International Journal of Minerals,Metallurgy and Materials 2000年第4期14卷 318-322页

作者： Songfeng Lu, Zhengding Lu (college of Computer science and Technology, huazhong university of science and Technology, wuhan 430074, china) college of Computer science and Technology Huazhong University of Science and Technology Wuhan 430074 China

In traditional data clustering, similarity of a cluster of objects is measured by distance between objects. Such measures are not appropriate for categorical data. A new clustering criterion to determine the similarity between points with categorical attributes is pre- sented. Furthermore, a new clustering algorithm for categorical attributes is addressed. A single scan of the dataset yields a good clus- tering, and more additional passes can be used to improve the quality further.

关键词： data mining clustering similarity Information

Cu(Ⅱ) Potentiation of Alzheimer Aβ1-40 Cytotoxicity and Transition on its Secondary Structure

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Acta Biochimica et Biophysica Sinica 2006年第11期38卷 765-772页

作者： Xue-Ling DAI~1 Ya-Xuan SUN~2 Zhao-Feng JIANG~2* 1 college of life science,Capital normal university,Beijing 100037,china 2.college of Applied sciences and Humanities,Beijing Union university,Beijing 100083,china college of life science Capital Normal UniversityBeijing 100037 China college of Applied sciences and Humanities Beijing Union UniversityBeijing 100083 China

Mounting evidence has shown that dyshomeostasis of the redox-active biometals such as Cuand Fe can lead to oxidative stress,which plays a key role in the neuropathology of Alzheimer's disease（AD）.Here we demonstrate that with the formation of Cu（Ⅱ）·Aβ1-40 complexes,copper markedly potentiatesthe neurotoxicity exhibited by β-amyloid peptide （Aβ）.A greater amount of hydrogen peroxide was releasedwhen Cu（Ⅱ）·Aβ1-40 complexes was added to the xanthine oxidase/xanthine system detected by potassiumiodide *** bound to Aβ1-40 was observed by electron paramagnetic resonance（EPR） *** dichroism （CD） studies indicated that copper chelation could cause a structuraltransition of Aβ.The addition of copper to Aβ introduced an increase on β-sheet as well as α-helix,whichmay be responsible for the aggregation of Aβ.We hypothesized that Aβ aggregation induced by copper maybe responsible for local injury in *** interaction between Cu2+and Aβ also provides a possible mechanismfor the enrichment of metal ions in amyloid plaques in the AD brain.

关键词： Alzheimer’s disease Cu(Ⅱ)·Aβ1-40 complex neuron injury Aβ secondary structure

Bose-Einstein Condensation in Linear Sigma Model at Hartree Approximation

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Communications in Theoretical Physics 2008年第5期49卷 1261-1264页

作者： SHU Song~(1,+) LI Jia-Rong~21 Faculty of Physics and Electronic Technology,Hubei university,wuhan 430062,china2 Institute of Particle Physics,huazhong normal university,wuhan 430079,china Faculty of Physics and Electronic Technology Hubei University Wuhan 430062 China Institute of Particle Physics Huazhong Normal University Wuhan 430079 China

The BEC of charged pions is investigated in the framework of O(4) linear sigma *** using Cornwall-Jackiw- Tomboulis formalism,we have derived the gap equations for the effective masses of the mesons at finite tempera-ture and finite isospin *** critical temperature and phase diagram of BEC are discussed in the non-chiral limitat Hartree approximation.

关键词： finite temperature field theory Bose-Einstein condensation phase transitions

Peplomycin induces G1-phase specific apoptosis in liver carcinoma cell line Bel-7402 involving G2-phase arrest

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Acta Pharmacologica Sinica 2004年第12期25卷 132-138页

作者： Hong-ying CHEN2, Cong-yi ZHENG2, Guo-lin ZOU2, Da-xing XIE3, Jian-ping GONG3 2college of life sciences, wuhan university, wuhan 430072 3Cancer Research Institute, Tongji Hospital, TongjiMedical college, huazhong university of science and Technology, wuhan 430072, china college of life sciences Wuhan University Wuhan 430072 China

AIM: To investigate the mechanism of peplomycin (PEP)-induced apoptosis in liver carcinoma cell line (Bel-7402). METHODS: Growth inhibition by PEP was analyzed using 3- 4,5-Dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT) assay. Apoptotic cells were detected using Hoechest 33258 staining, and confirmed by flow cytometric analysis and DNA fragmentation analysis. The expression of cyclin A and B1 were determined by flow cytometry and Western blot. Annexin V assay was measured by flow cytometric analysis. RESULTS: PEP induced apoptosis and then inhibited cell proliferation in liver carcinoma cell line Bel-7402. Cells treated with PEP 50 μmol/Lfor 15 h were arrested in G2-phase with dramatical expression of cyclin A and a little change in cyclin B1. Almost all the apoptosis occurred in cells undergoing the G1-phase after treatment for 24 h. CONCLUSION: Peplomycin induced G1-phase specific apoptosis in Bel-7402 involving G2-phase arrest.

关键词： peplomycin Bel-7402 cells apoptosis cyclins cell cycle flow cytometry