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CT-guided needle biopsy through mandibular area for the diagnosis of nasopharyngeal carcinoma in the parapharyngeal space

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chinese Journal of Cancer 2010年第8期29卷 768-773页

作者： Yong Su1,2. Chong Zhao1,2. Wen-Jie Li1,2. Xue-Ying Deng1,3, Rui-Fang Zeng1,2. Nian-Ji Cui1,2. Tai-Xiang Lu1,2.1 State Key Laboratory of Oncology in South china, guangzhou, Guangdong 510060, P. R. china 2.Department of Radiation Oncology, Sun Yat-sen University Cancer center, guangzhou, Guangdong 510060, P. R. china 3 Department of Radiotherapy, Dongguan People’s Hospital, Dongguan, Guangdong 52.000, P. R. china Department of Radiation Oncology Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Guangdong Guangzhou 510060 Department of Radiotherapy Dongguan People's Hospital State Key Laboratory of Oncology in South China Guangdong Guangzhou 510060

Background and Objective: The primary submucous type of nasopharyngeal carcinoma (NPC) or the recurrent NPC in the parapharyngeal space is difficult to be diagnosed histologically by conventional biopsy because of the obstruction of the surrounding structures. This study was performed to evaluate the needle biopsy approach through the madibular area into the parapharyngeal space under the guidance of computed tomography (CT) for NPC. Methods: Between July 6, 2.05 and October 2., 2.09, a total of 6 patients were enrolled into the study. Two patients with cervical lymph node metastasis were clinically suspicious of NPC according to their clinical manifestations. However, no cancer cell could be found by repeated nasopharyngeal biopsies followed by histologic examinations. The other 4 patients were diagnosed with recurrent NPCs by magnetic resonance imaging (MRI) or/and positron emission tomography (PET)-CT scan, showing tumors in the parapharyngeal spaces in 3 patients and enlarged retropharyngeal lymph node in 1 patient. The CT-guided puncture was performed through the mandibular skin and the cutting needle biopsy was taken at the parapharyngeal space focus. results: All the cutting needle biopsies of projected locations have been performed safely. Finally, all the 7 specimens met the requirement of pathologic diagnosis and the cases were all confirmed histologically to be NPCs. The main complication was mild ache at the puncture point. No blood vessel or nerve was injured and no patient needed special treatment. Conclusions: The CT-guided puncture biopsy of the parapharyngeal space through the mandibular area is simple and feasible. It can be an additional option for routine nasopharyngeal biopsy.

关键词： CT扫描病理诊断鼻咽癌活检间隙穿刺引导正电子发射断层扫描

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Studies on Human Fetal Lens Crystallins Under Oxidative Stress and Protective Effects of Tea Polyphenols

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眼科学报 1998年第3期14卷 170-175页

作者： Hui Xiang, Suhua Pan, Shaozhen LiGuangdong Provincial Corps Hospital, chinese People’ s Armed Police Forces, guangzhou 510010,{2. Zhongshan Ophthalmic center, Sun Yat-sen University of Medical sciences, guangzhou 510060,{2. Guangdong Provincial Corps Hospital Chinese People's Armed Police Forces Guangzhou 510010 China

Purpose: To investigate the oxidative modification of water-soluble crystallins of human fetal lens with H2.2.and fourteen metal ions with or without EDTA. Tea-polyphenols (TP) was added to above solutions in order to testing their antioxidative abilities. Methods: The experiments were performed at 37℃ with final concentration of 2.5mg/ml protein, 0.1 mM metal ions, 0.3 mM EDTA and 1.0 mM H2.2. Then the TP was added to the solution with CuSO4 and H2.2. after 5 or 2. hours, the crystallins were analysed with SDS-PAGE and *** : There were marked oxidative modifications of lens protein in H2.2.and copper without EDTA. In SDS-PAGE patterns, we found an increase in those species above of bands higher than 30 kD and some diffuse bands from 30 to 17 kD after 5 hours. In IEF patterns, there were a general increase on acidity with loss of the more basic species. When the TP was added, there was not any difference with control ***: The results indicate that exposure of water-soluble

关键词：人胎儿晶状体晶体蛋白氧化变性抗氧化作用多酚

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高温液态水预处理桉木水解动力学的研究

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太阳能学报 2011年第10期32卷 1487-1493页

作者：庄新姝亓伟袁振宏余强王琼马隆龙吴创之中国科学院广州能源研究所中国科学院可再生能源与天然气水合物重点实验室广州510640 中国科学院研究生院北京100049

在间歇式反应釜中对高温液态水预处理桉木的反应情况进行研究。通过考察得到高温液态水预处理桉木的最佳工艺条件为反应温度180℃、反应时间2.min,木糖得率为86.46%;分析了桉木水解的反应历程,建立了桉木在高温液态水中水解的动力学方程... 详细信息

在间歇式反应釜中对高温液态水预处理桉木的反应情况进行研究。通过考察得到高温液态水预处理桉木的最佳工艺条件为反应温度180℃、反应时间2.min,木糖得率为86.46%;分析了桉木水解的反应历程,建立了桉木在高温液态水中水解的动力学方程,通过计算值与实验值的对比,认为该动力学方程可较准确地描述桉木在高温液态水中的反应历程。

关键词：高温液态水桉木木糖水解动力学

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Treatment outcomes for different subgroups of nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy

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chinese Journal of Cancer 2011年第8期30卷 565-573页

作者： Sheng-Fa Su 1,2.3,Fei Han 1,2.Chong Zhao 1,2.Ying Huang 1,2.Chun-Yan Chen 1,2.Wei-Wei Xiao 1,2.Jia-Xin Li 1,2.and Tai-Xiang Lu 1,2.1 State Key Laboratory of Oncology in South china,guangzhou,Guangdong 510060,P.R.{2. 2.Department of Radiation Oncology,Sun Yat-sen University Cancer center,guangzhou,Guangdong 510060,P.R.{2. 3 Department of Oncology,Guiyang Medical College Hospital,Tumor Hospital of Guizhou,Guiyang,Guizhou 550003,P.R.{2.. State Key Laboratory of Oncology in South china Guangzhou Guangdong 510060 P. R. China.

Although many studies have investigated intensity-modulated radiation therapy (IMRT) for nasopharyngeal carcinoma (NPC),sample sizes in the reported studies are usually small and different in outcomes in different T and N subgroups are seldom ***,we evaluated the outcomes of NPC patients treated with IMRT and further explored treatment strategy to improve such *** collected clinical data of 865 NPC patients treated with IMRT alone or in combination with chemotherapy,and classified all cases into the following prognostic categories according to different TNM stages:early stage group (T1-2.0-1M0),advanced local disease group (T3-4N0-1M0),advanced nodal disease group (T1-2.2.3M0),and advanced locoregional disease group (T3-4N2.3M0).The 5-year overall survival (OS),local relapse-free survival (LRFS),and distant metastases-free survival (DMFS) were 83.0%,90.4%,and 84.0%,*** early disease group had the lowest treatment failure rate,with a 5-year OS of 95.6%.The advanced local disease group and advanced nodal disease group had similar failure pattern and treatment outcomes as well as similar hazard ratios for death (4.2.0 and 4.62.,respectively).The advanced locoregional disease group had the highest incidence of relapse and death,with a 5-year DMFS and OS of 62.3% and 62.2.,respectively,and a hazard ratio for death of *** with IMRT alone,IMRT in combination with chemotherapy provided no significant benefit to locoregionally advanced *** results suggest that the decision of treatment strategy for NPC patients should consider combinations of T and N stages,and that IMRT alone for early stage NPC patients can produce satisfactory ***,for advanced local,nodal,and locoregional disease groups,a combination of chemotherapy and radiotherapy is recommended.

关键词：放射治疗强度调制鼻咽癌患者调控样本大小临床资料结合治疗

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The Utilization of modified BCR Three-step Sequential Extraction Procedure for The Fractionation of Cd,Cr,Cu,Ni,Pb and Zn in Soil reference Materials of china

The Utilization of modified BCR Three-step Sequential Extrac...

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第三十五届国际光谱会议

作者： C.Y.Zhang~(1,2. P.G.Peng~(2.) ~1 Analytical center,Guangdong Institute of Ecoenvironmental and Soil sciences,{2. 510650,china ~2.State Key Laboratory of Organic Geochemistry,{2. Institute of Geochemistry chinese academy of sciences,{2. 510640,china

＜正＞A modified three-step sequential extraction procedure for the fractionation of heavy metals,proposed by the Commission of the European Communities Bureau of references （BCR） has been applied to the chinese reference materials of soils （GSS-6,GSS-7 and GSS-16）,which represent different types of soils in Guangdong province,china. Analyses were carried out by inductively coupled plasma atomic emission spectrometry or graphite furnace atomic absorption spectrometry （ICP-AES or GFAAS）.The fractions

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Integral spinor norms in dyadic local fields Ⅲ

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Science china Mathematics 2010年第9期53卷 2425-2446页

作者： L JianRui1 & XU Fei2.1Department of Mathematics,Jinan University,guangzhou 510632.china 2.chool of Mathematics,Capital Normal University,Beijing 100048,china Department of Mathematics Jinan University Guangzhou China School of Mathematics Capital Normal University Beijing China

In this paper we give an alternative computation of integral spinor norms over dyadic local fields by using the Jordan decomposition of *** particular,we emphasize the striking similarity between the theory over dyadi... 详细信息

关键词： integral lattice spinor norm Jordan decomposition

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Applications of functionalized ionic liquids

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Science china Chemistry 2006年第5期49卷 385-401页

作者： LI Xuehui1, ZHAO Dongbin2.3, FEI Zhaofu2.& WANG Lefu1 1. Department of Chemical Engineering, Guangdong Provincial Laboratory of Green Chemical Technology, South china Uni-versity of Technology, guangzhou 510641, china 2. Swiss Federal Institute of Technology, Lausanne, EPFL, CH-1015 Lausanne, Switzerland 3. PKU Green Chemistry center, Beijing National Laboratory for Molecular sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, china Department of Chemical Engineering Guangdong Provincial Laboratory of Green Chemical Technology South China University of Technology Guangzhou China Lausanne EPFL Swiss Federal Institute of Technology Lausanne Switzerland PKU Green Chemistry center Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular Engineering Peking University Beijing China

recent developments of the synthesis and applications of functionalized ionic liquids (including dual-functionalized ionic liquids) have been highlighted in this review. Ionic liquids are at-tracting attention as alternative solvents in green chemistry, but as more functionalized ILs are pre-pared, a greater number of applications in increasingly diverse fields are found.

关键词： ionic liquids functionalized ionic liquids dual-functionallzed ionicliquids reaction media asymmetric synthesis nano-materials porous materials lubricants flue-gas desulfurization oil desul-furization

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Cryodamage to plasma membrane integrity in head and tail regions of human sperm

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Asian Journal of Andrology 2000年第2期2卷 135-138页

作者： Wei-Jie ZHU Xue-Gao LIU center for reproductive Immunology research, Jinan University, {2. 510632. china center for reproductive Immunology research Jinan University Guangzhou 510632 China

Aim: To investigate the effect of cryopreservation on the plasma membrane integrity in the head and tail regions ofindividual sperm, and the relationship between intact cryopreserved sperm and its motility and zona-free hamster oocytepenetration rate. Methods: The eosin Y exclusion and the hypoosmotic swelling tests were combined to form a sin-gle test (HOS-EY test) to identify the spermatozoa with four types of membrane integrity. results: After cryop-reservation, there was a marked decline in the percentage of spermatozoa with Type Ⅳ membrane integrity (head mem-brane intact/tail membrane intact), and a significant increase in those with Type Ⅰ (head membrane damaged/tail mem-brane damaged) and Type Ⅲ (head membrane damaged/tail membrane intact) membrane integrity (n = 50, P reas Type Ⅱ (head membrane intact/tailmembrane damaged) was uncommon after thawing. A high correlation was observed between the percentage of Type Ⅳintegrity and sperm motility ( n = 50, r = 0.74, P re usuallylower than those of post-thaw motility in most cryopreserved samples. The value of Type Ⅳ integrity did not correlatewith the sperm penetration rate ( n = 2., r = 0.2., P > 0.05). Conclusion: (1) The HOS-EY test has the advan-tage of showing four patterns of membrane integrity in individual spermatozoon; (2. Cryopreservation causes a signifi-cant membrane rupture in the head and tail regions of spermatozoa; Type Ⅲ is the main transitional state of membranecryodamage; (3) Cryodamage to head and tail membrane may occur independently; the presence of an intact tail mem-brane does not necessarily indicate the intacmess of head membrane. (4) Intact membranes are closely related to post-thaw motility, but do not reflect the fertilizing potential.

关键词： spermatozoa cryopreservation cell membrane supravital staining hypoosmotic swelling test

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Effects of temperature and organic and inorganic nutrients on the growth of Chattonella marina (Raphidophyceae)from the Daya Bay,South china Sea

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Acta Oceanologica Sinica 2011年第3期30卷 124-131页

作者： WANG Zhaohui YUAN Meiling LIANG Yu LU Sollghui College of Life Science and Technology Jinan University Guangzhou 510632 China Engineering research center of Tropical and Subtropical Aquatic Ecological Engineering Ministry of Education Guangzhou 510632 China

The effects of temperature and different forms of nutrients on Chattonella marina growth have been investigated in strains isolated from the Daya Bay, the South china Sea. The strain of C. marina preferred high temperatures, with an optimal temperature of 2.℃, and 18℃ was the minimum for its survival. Higher cell number and growth rate were obtained in high nitrogen and phosphorus concentrations （500 μg/L, 74μg/L） than under nutrient limitation. Nitrogen influenced the growth most, as the specific growth rate and maximum cell density were lower in nitrogen- limited cultures than noted under phosphorus limitation or under limitation from both. C. marina was capable of using many kinds of organic nitrogen sources including L-serine （L-Ser）, glycine （Gly）, alanine （Ala）, L-threonine （L-Thr）, glutamic acid （Glu） and urea, but could not utilize uric acid. Various forms of organic phosphorus compound such as glucose-6-phosphate （G6P）, sodium glycerophosphate （GYP）, adenosine triphosphate （ATP）, adenosine monophosphate （AMP）, cyti- dine monophosphate （CMP）, guanosine monophosphate （GMP）, uridine monophosphate （UMP）, 4-nitrophenylphosphate （NPP） and triethyl phosphate （TEP） supported the growth as well. Algal cells had the ability to sustain growth under nitrogenand/or phosphorus-free conditions particularly under phosphorus depleted condition. These results led to the hypothesis that high loading of nitrogen has played an important role in frequent C. marina blooms in the past decade, and its capability for utilization of diverse forms of organic nutrients and growth in low nutrient conditions make this species a likely recurrent dominant in the Daya Bay phytoplankton assemblages, visible as more frequent blooms.

关键词： Chattonella marina growth inorganic and organic nutrients salinity temperature

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An improvement on summer regional climate simulation over East china: Importance of data assimilation of soil moisture

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chinese Science Bulletin 2010年第9期55卷 867-873页

作者： HU YaMin1,2.3, DING YiHui4 & LIAO Fei2.1 Institute of Tropical and Marine Meteorology, china Meteorological Administration, guangzhou 510080, china 2.Guangdong Climate center, guangzhou 510080, china 3 chinese academy of Meteorological sciences, Beijing 100081, china 4 National Climate center, china Meteorological Administration, Beijing 100081, china

The Newtonian relaxation is used to assimilate data from the Second Global Soil Wetness Project (GSWP2. into the initial field for soil moisture in a regional climate model (i.e., BCC_regCM 1.0, hereinafter called regCM). The results show that different nudging parameters can improve the simulation of the air temperature and the precipitation to some extent in summertime season over East china. When the nudging intensity is 0.5 and nudging duration is 5 days, the result is desirable. Introducing the data assimilation of soil moisture into regCM, the amelioration is not only in the spatial distribution pattern but also in the magnitude of the temperature and the precipitation. More specifically, the assimilation experiments have corrected the systematical cold bias of the air temperature and the precipitation on the low side, which is much closer to the observation compared with the control experiment. On the whole, the assimilation experiments shed light on the fact that the simulated bias in the original regCM may be affected by the description of soil moisture in the land surface process. Therefore, the effect of soil moisture in regCM should be paid more attention in the future.

关键词： soil moisture Newtonian relaxation data assimilation regional climate simulation

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