检索结果-南通市图书馆

Ultrasonography in predicting and screening liver cirrhosis in children:A preliminary study

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2003年第10期9卷 2348-2349页

作者： Jia-An Zhu Bing Hu, department of Ultrasound in Medicine, Affiliated Sixth People’s hospital, {2. Jiaotong university, {2. 2.02.3, china department of Ultrasound in Medicine Shanghai Sixth People's Hospital Shanghai Jiaotong University Shanghai 200233 China. zhujiaan@***

AIM: To evaluate the value of ultrasonography in predicting and screening liver cirrhosis in ***: Twenty-eight children with liver cirrhosis of various etiologies were examined by routine ultrasonography.A percutaneous liver biopsy guided by ultrasound was also performed on each patient, and the results of liver biopsy and ultrasonography were ***: When compared with the biopsy results,ultrasonography in combination of clinical and laboratory findings gave accurate diagnoses of children liver *** ultrasound imaging of children with liver cirrhosis revealed abnormal characteristics, these images were not specific to this disease, thus reinforcing the necessity of ultrasound-guided liver biopsy in the diagnosis of children liver ***: Ultrasonography is reliable in the diagnosis of children liver cirrhosis, and its usefulness should be stressed in the screening and follow-up of high-risk pediatric patients.

关键词：肝硬化儿童诊断超声检查活组织检查

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

雷公藤单体T4治疗IgA肾病的实验研究

上海医学 2003年第S1期26卷 19-22页

作者：李江涛许晨李素孙向华马骏同济大学附属同济医院肾内科上海200065

目的　研究雷公藤单体T4对实验性IgA肾病的治疗作用。方法　肝叶切除 ,4、8周后静脉注射脂多糖 (LPS)制作IgA肾病模型 ,予该模型 12.0 μg·kg- 1 ·d- 1 雷公藤单体T4腹腔注射 4周。采用考马斯亮兰法测定 2.4h尿蛋白量 ,采用ELISA法测... 详细信息

目的　研究雷公藤单体T4对实验性IgA肾病的治疗作用。方法　肝叶切除 ,4、8周后静脉注射脂多糖 (LPS)制作IgA肾病模型 ,予该模型 12.0 μg·kg- 1 ·d- 1 雷公藤单体T4腹腔注射 4周。采用考马斯亮兰法测定 2.4h尿蛋白量 ,采用ELISA法测定血清IgA FN水平 ,采用免疫荧光法检测肾小球系膜区IgA的沉积。结果　雷公藤单体T4可抑制IgA肾病大鼠尿蛋白的产生 ,显著降低其血清IgA FN水平 ,明显减少肾小球系膜区IgA的沉积并改善其组织学病变。结论　雷公藤单体T4对该IgA肾病模型有明确治疗作用。其抑制系膜细胞增生、IgA系膜区沉积可能是通过降低血清IgA

关键词： IgA肾病雷公藤单体T4 IgA-纤维连接蛋白系膜细胞

在线全文

学校读者我要写书评

暂无评论

化疗泵不同置入方式在肺癌治疗中的应用分析

上海医学 2003年第S1期26卷 75-76,111页

作者：周永新冯靖张鹏王永武同济大学附属同济医院胸心外科上海200065

目的　探讨化疗泵的不同置入方式在肺癌治疗中的疗效及价值。方法　回顾性分析我院 1997年1月～ 2.0 0 2. 7月行化疗泵置入化疗的无手术指征或条件的非小细胞肺癌患者 5 8例 ,其中行超选肺动脉化疗泵置入化疗 (超选组 ) 2.8例 ,行右心... 详细信息

目的　探讨化疗泵的不同置入方式在肺癌治疗中的疗效及价值。方法　回顾性分析我院 1997年1月～ 2.0 0 2. 7月行化疗泵置入化疗的无手术指征或条件的非小细胞肺癌患者 5 8例 ,其中行超选肺动脉化疗泵置入化疗 (超选组 ) 2.8例 ,行右心房化疗泵置入化疗 (右心房组 ) 3 0例。根据WHO实体瘤客观疗效评定标准评价近期疗效 ,并随访观察远期疗效。结果　超选组的近期疗效优于右心房组 (P >0 .0 5 ) ,生存分析超选组生存率高于右心房组。两组Ⅳ期病例在远、近疗效方面的差异无显著性 ,超选组导管移位的并发症高于右心房组。结论　化疗泵在无手术指征或条件的非小细胞肺癌患者的治疗中疗效明确 ,而超选化疗泵的疗效优于右心房化疗泵。

关键词：肺癌化疗泵化疗

imaging Diagnosis of Monostotic Fibrous Dysplasia in Thoracic and Lumbar Spine Vertebrae

在线全文

学校读者我要写书评

暂无评论

Journal of Huazhong university of Science and Technology(Medical Sciences) 2007年第6期27卷 684-686页

作者：杨彩虹朱波陈安民 department of Orthopedics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

The X-ray radiograph, CT scan and MRI appearance of 5 patients with pathologically proven fibrous dysplasia in thoracic and lumbar spine vertebrae were retrospectively analyzed. Plain radiographs, CT scans and MR images showed the presentation of eccentric lesion with intact cortex bone and marginal sclerosis in vertebral bodies without involvement of vertebral appendix and ex- traosseous soft tissue. The lesion masses were round （one being oval-shaped） and radiolucent in plain radiographs and CT scans. Homogeneous long signal was observed on Tl weighted image and strongly enhanced when gadolinium was administered. On T2.weighted MRI, short signal was found in the anterior part of the mass, long signal in the posterior part, and short and slight long signal in the middle part, without partitioning and laminating change. There was a good correlation between radiological features and surgical findings. These findings may be useful to diagnose fibrous dysplasia m spree.

关键词： spine fibrous dysplasia radiology magnetic resonance imaging

imaging diagnosis of pancreato-biliary diseases: A control study

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2003年第12期9卷 2824-2827页

作者： Liang Zhong Qiu-Ying Yao Lei Li Jian-Rong Xu department of Radiology,Renji hospital,{2. Second Medical university,{2. 2.0001,china department of Radiology Renji Hospital Shanghai Second Medical University Shanghai 200001 China. zhong-liang@***

AIM: To evaluate the clinical value of various imageological methods in diagnosing the pancreato-biliary diseases and to seek the optimal ***: Eighty-two cases of pancreato-biliary diseases confirmed by surgery and pathology were analyzed. There were 38 cases of cholelithiasis, 34 cases of pancreato-biliary tumors and 10 other cases. The imageological methods included B-US, CT, ERCP, PTC, cross-sectional MRI and MR cholangiopancreatography (MRCP).RESULTS: The accuracy rate of MRCP in detecting the location of pancreato-biliary obstruction was 100 %. In differentiating malignant from benign obstruction, the sensitivity of the combination of MRCP and cross-sectional MRI was 82.3 %, the specificity was 93.8 %, and the accuracy rate was 89.0 % . The accuracy rate for determining the nature of obstruction was 87.8 %, which was superior to that of B-US (P=0.0000) and CT (P=0.0330),but there was no significant difference between direct cholangiopancreatography and the combination of MRCP and conventional MRI (P=0.6666).CONCLUSION: In most cases, MRCP can substitute direct cholangiopancreatography for diagnosis. The combination of MRCP and cross-sectional MRI should be considered as an important means in diagnosing the pancreato-biliary diseases, pre-operative assessment and post-operative follow-ups.

关键词：胰胆系疾病影像学诊断胆管阻塞临床研究 B-US ERCP

阿米替林与帕罗西汀改善抑郁及焦虑症状的对照研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

上海医学 2003年第S1期26卷 60-61,65页

作者：刘美兰吴文源李春波同济大学附属同济医院心身科上海200065

目的　比较阿米替林与帕罗西汀改善抑郁及焦虑症状的疗效及其不良事件。方法　予治疗剂量的阿米替林与帕罗西汀治疗患者 ,观察 6周 ,用汉密顿抑郁量表 (HAMD)、汉密顿焦虑量表 (HAMA)及TESS不良反应量表评价疗效及不良事件。结果　两组... 详细信息

目的　比较阿米替林与帕罗西汀改善抑郁及焦虑症状的疗效及其不良事件。方法　予治疗剂量的阿米替林与帕罗西汀治疗患者 ,观察 6周 ,用汉密顿抑郁量表 (HAMD)、汉密顿焦虑量表 (HAMA)及TESS不良反应量表评价疗效及不良事件。结果　两组药物抗抑郁效果的差异无显著性 ,但帕罗西汀抗焦虑作用强于阿米替林 (P <0 .0 1) ,且不良事件较少 (P <0 .0 1)。结论　帕罗西汀能较好地改善抑郁及焦虑症状。

关键词：抗抑郁药物抑郁焦虑

Effect of knockout of cyclinD1 on proliferation and the cell cycle of neural stem cell

在线全文

学校读者我要写书评

暂无评论

Effect of knockout of cyclinD1 on proliferation and the cell...

Experimental Study of Helical CT Virtual Endosecopy of the Thoracic Aorta in the Rabbit Model of Atherosclerosis

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Jun-Fang MA,Wei WANG*,Min-Jie XIE,Zhi-Yuan YU department of Neurology,Affiliated tongji {2. of tongji Medical College,Huazhong university of Science and Technology,Wuhan 430030,china

Objective CyclinD1 is a D-type cyclins synthesized and binds CDK4 and CDK6,which prompts cells to enter the G1 *** studies have been done on the relationship with the cyclinD1 with *** aim to investigate the effect of knockout of cyclinD1 on proliferation and the cell cycle of neural stem *** The NSCs from the cyclinD1 mouse were isolated by microdissection and mechanical blowing and cultured with serum-free suspension *** proliferation of neural stem cell was identified by stem cell cloning efficiency and MTT *** cell cycle of neural stem cell was measured by flow *** Cloning efficiency and the average OD value by MTT assay of the cyclinD1 mouse were significantly less compared with hemizygous and wild *** analysis showed that the cells were arrested in G/G phase with the index of cells in G/G *** Knockout of cyclinD1 inhibited the proliferation of neural stem cell and the cells were arrested in G/G phase.

关键词： proliferation neural stem cell the cell cycle cyclinD1 knockout

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Experimental Study of Helical CT Virtual Endosecopy of the T...

EFFECT OF SHORT-TERM SOFT CONTACT LENS WEAR ON HUMAN OCULAR ABERRATIONS

CCAST“北京第二次医学影像物理和工程”国际研讨会

作者： Yang Zhen Yan Mao Xin Qing Zheng Shao Qiang Zhang Song Hua tongji hospital, tongji university, 389 Xin Cun Road, shanghai 2.0065

Objective To investigate the diagnostic value of helical CT Virtual endoscopy (CTVE) for atherosclerosis (AS), and to promote the image quality by the changing of the threshold. Mthods In order to create the animal model of atherosclerosis, 15 male New Zealand white rabbits were fed with cholesterol diet for three months. We scanned the thoracic aorta of the model rabbit of atherosclerosis after injecting the contrast agents and transferred the volume image data to the graphic workstation with a virtual endoscope software in order to reconstruct the CTVE images. The findings of CTVE images were compared with that on pathological examination. We compared the mean attenuation of the aorta and the threshold at which artifacts appeared, then made correlation analysis. Results The diagnostic sensitivity of the atherosclerosis using CTVE is 68.75%, specifity 71.43%, false positive ratio 2..57%, false negative ratio 31.2.%, positive prodictive value 73.33% and negative prodictive value 66.67%, respectively. A correlation was found between the findings on the CTVE images and those at the examination of pathology(r=0.32., p2., p<0.05;r=0.611, p<0.05). Conclusion CTVE can provide diagnostic information for the atherosclerosis and serve as a noninvasive supplemental method to other diagnostic methods. An artifact-free threshold range can be predicted according to the aortic attenuation after contrast enhancement and the artifacts can be minimized.

关键词： Atherosclerosis Tomography X-ray computed Virtual Endoscopy Pathology Rabbit

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of shanghai Second Medical university(Foreign Language Edition) 2009年第2期21卷 95-100页

作者：于靖陈佚卉陈辉盛敏杰 Division of Ophthalmology Shanghai 10th People's Hospital Tongji University department of Ophthalmology Affiliated Hospital of Nantong University

Objective To evaluate the effect of short-term soft contact lens （SCLs） wearing on human ocular aberrations （ HOA ）. Methods This prospective study included 50 eyes of 50 young volunteers wearing SCLs for 1 month. The ocular aberrations were measured by Allegretto Wavefront Analyzer. The root-mean-square （RMS） values of the general （RMSG） , higher-order （RMSH） , first to sixth order （ RMS1 to RMS6） and aberration coefficients were analyzed. Results There were no significant differences in the mean values of RMSG, RMSH, RMS1 to RMS6 （ P 〉 0. 05 ） and changes of absolute values of aberration coefficients between baseline and various visits after SCLs discontinuation. However, at d I after the discontinuation of SCLs, changes in coefficient values of the third-order aberrations （ C6 to C9 ） were slightly higher than others, and C7 was the highest. The increase factors of RMS values were higher at 1 week and lower at the 2.week visit after SCLs discontinuation. The uniformity of dominating type in HOA and the corneal topography form was both about 60% after discontinuation of SCLs. The corneal thickness increased after SCLs wear and gradually decreased to baseline until 1 month discontinuation of SCLs. Conclusion The effect of short-term SCLs wear on human ocular aberrations is slight but profound. A month or more wait should be allowed before the short-term SCLs wearers are scheduled for wavefronted-guided LASIK.

关键词： aberration contact lens corneal topography wavefront analyzer