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Blue light-specific regulation of CIB1 protein expression in Arabidopsis

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Blue light-specific regulation of CIB1 protein expression in...

2.11全国植物生物学研讨会

作者： Hongtao Liu~1 Chentao Lin~2.1.Institute of Plant Physiol & Ecology Chinese Academy of Sciences 2.department of Molecular Cell and Developmental Biology university of {2. los angeles

Cryptochromes(CRY) are photolyase-like blue-light receptors that mediate light responses in plants and *** plant cryptochromes act in response to blue light is not well *** have r

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Blue light-specific regulation of CIB1 protein expression in Arabidopsis

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Blue light-specific regulation of CIB1 protein expression in...

2.11全国植物生物学研讨会

作者： Hongtao Liu~1,Chentao Lin~2.1.Institute of Plant Physiol & Ecology,Chinese Academy of Sciences 2.department of Molecular,Cell and Developmental Biology,university of {2.,los angeles

Cryptochromes(CRY) are photolyase-like blue-light receptors that mediate light responses in plants and *** plant cryptochromes act in response to blue light is not well *** have recently reported the identification and characterization of the Arabidopsis CIB 1(cryptochrome-interacting basic-helix-loop-helix).CIB1 interacts with CRY2.cryptochrome 2. in a blue light-specific manner,and it acts with additional CIBl-related proteins to promote CRY2.dependent activation of FT gene expression and floral initiation and CIB1 binds to the FT protmoter in *** proposed that the blue light-dependent interaction of cryptochrome(s) with CIB1 and CIBl-related proteins represents an

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美国史学界对流行文化与其受众关系的研究

吉林大学社会科学学报 2006年第1期46卷 156-160页

作者：王霄飞南加利福尼亚大学历史学系美国洛杉矶ca90007

流行文化研究,是当今美国的热门学术领域;对流行文化与其受众关系的探讨,则是其中的一个重要课题。美国史学界关于这一课题的研究,不仅涉及到对某些历史事实的叙述,更是透视美国史学理论发展的一个重要窗口。综述“无权”与“有权”两... 详细信息

流行文化研究,是当今美国的热门学术领域;对流行文化与其受众关系的探讨,则是其中的一个重要课题。美国史学界关于这一课题的研究,不仅涉及到对某些历史事实的叙述,更是透视美国史学理论发展的一个重要窗口。综述“无权”与“有权”两种观点的主要著作,勾勒美国史学界流行文化受众研究的发展历程,或许有助于把握美国当代文化史研究的发展方向,有利于进一步深入理解流行文化研究在史学界的发展脉络。此外,西方马克思主义的一支———法兰克福学派对流行文化问题的探讨对美国史学界关于受众研究也产生了重大影响。

关键词：美国流行文化有权受众无权受众工人阶级

NORMAL-SLIP ALONG THE NORTHERN ALTYN TAGH FAULT, NORTH TIBET

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地学前缘 2000年第S1期7卷 237-238页

作者： Yin An 1, George Gehrels 2. Chen Xunhua 3, Wang Xiao\|Feng 3, T. Mark Harrison 1, Shen Jie 1[WT5,5”BX](1 department of Earth and Space Sciences and Institute of Geophysics and Planetary Physics, university of {2., los angeles, CA 90095\

The east\|west striking Northern Altyn Tagh Fault, about 2.0km long between Bashkaogong (90°E, 39°2.′N) and Lapeiquan (92.15′E, 39°2.′N), was previously mapped as a north\|dipping thrust, juxtaposing late Archean\|Mesoproterozoic gneisses in the hanging wall over Paleozoic volcanics, plutons, turbidite, and melange complexes in the footwall. In order to estimate the total magnitude of slip along the Cenozoic Altyn Tagh fault, we conducted geologic mapping along four traverses across the Jinyan Shan where the fault lies. Our field observations suggest that the fault is south\|dipping, with dip angles varying from 2.° in the east to about 40° in the west. The eastern fault zone exhibits mylonitic fabrics, whereas the western fault zone is characterized by cataclastic deformation. Kinematic indicators in the ductily deformed mylonitic shear zone consistently show a top\|to\|the\|south sense of shear, suggesting that the Northern Altyn Tagh fault is a south\|dipping normal fault, not a north\|dipping thrust.. The ductile shear zone is typically 30～40m thick, consisting of highly sheared metasediments (pelite and marble), granites, and granitic *** latter are systematically cut by small\|scale, south\|dipping ductile normal faults with displacements between 10s of cm to several meters, forming spectacular asymmetric boudinages in the sheared meta\|pelite *** minimum displacement along the detachment is about 2.km, as measured by the north\|south width of the exposed footwall gneisses. We renamed the Northern Altyn Tagh Fault in the Jinyan Shan region as the Lapeiquan detachment fault to avoid confusion with other east\|west trending Cenozoic faults to the west along the northern edge of the Altyn Tagh range (e.g., the Cenozoic Jianglisai fault near Qiemo), collectively known as the Northern Altyn Tagh fault system (see Cowgill et al., Geology,in press). The lower age bound of the Lapeiquan fault is Ordovician, as the fault cuts Ordovician volcanics and plut

关键词： detachment fault Northern Altyn Tagh Fault Tibet

Efficient mid-infrared single-photon detection using superconducting NbTiN nanowires with high time resolution in a Gifford-McMahon cryocooler

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Photonics Research 2022年第4期10卷 1063-1070页

作者： Jin Chang Johannes W.N.los Ronan Gourgues Stephan Steinhauer S.N.Dorenbos Silvania F.Pereira HPaul Urbach Val Zwiller Iman Esmaeil Zadeh Optics Research Group ImPhys DepartmentFaculty of Applied SciencesDelft University of TechnologyDelft 2628 CJThe Netherlands Single Quantum B.V. Delft 2628 CJThe Netherlands KTH Royal Institute of Technology Department of Applied PhysicsAlbanova University Centre10691 StockholmSweden

Shortly after their inception, superconducting nanowire single-photon detectors(SNSPDs) became the leading quantum light detection technology. With the capability of detecting single-photons with near-unity efficiency,high time resolution, low dark count rate, and fast recovery time, SNSPDs outperform conventional single-photon detection techniques. However, detecting lower energy single photons(lose to a nanosecond), and by operating them in complex milli Kelvin(mK) dilution refrigerators. In this work,we provide an alternative approach with SNSPDs fabricated from 5 to 9.5 nm thick NbTiN superconducting films and devices operated in conventional Gifford-McMahon cryocoolers. By optimizing the superconducting film deposition process, film thickness, and nanowire design, our fiber-coupled devices achieved >70% system detection efficiency(SDE) at 2.μm and sub-15 ps timing jitter. Furthermore, detectors from the same batch demonstrated unity internal detection efficiency at 3 μm and 80% internal efficiency at 4 μm, paving the road for an efficient mid-infrared single-photon detection technology with unparalleled time resolution and without mK cooling requirements. We also systematically studied the dark count rates(DCRs) of our detectors coupled to different types of mid-infrared optical fibers and blackbody radiation filters. This offers insight into the trade-off between bandwidth and DCRs for mid-infrared SNSPDs. To conclude, this paper significantly extends the working wavelength range for SNSPDs made from polycrystalline NbTiN to 1.5–4 μm, and we expect quantum optics experiments and applications in the mid-infrared range to benefit from this far-reaching technology.

关键词： nanowires technology SNSPD

Surface electrocardiogram and action potential in mice lacking urea transporter UT-B

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Science China(Life Sciences) 2009年第5期52卷 474-478页

作者： MENG Yan1, ZHAO ChunYan2. ZHANG XueXin2. ZHAO HuaShan1, GUO LiRong1, Lü Bin1, ZHAO XueJian1& YANG BaoXue1,3 1 department of Pathophysiology, School of Basic Medicine, Jilin university, Changchun 13002., China 2.department of Physiology, School of Basic Medicine, Jilin university, Changchun 13002., China 3 department of Medicine, university of california, San Francisco CA 94143, usa department of Pathophysiology School of Basic Medicine Jilin University Changchun China department of Physiology School of Basic Medicine Jilin University Changchun China department of Medicine University of California San Francisco USA

UT-B is a urea transporter protein expressed in the kidney and in many non-renal tissues including erythrocytes, brain, heart, bladder and the testis. The objective of this study was to determine the phenotype of UT-B deletion in the heart. UT-B expression in the heart was studied in wild-type mice vs UT-B null mice by utilizing RT-PCR and Western blot. A surface electrocardiogram (ECG) recording (lead II) was measured in wild-type mice and UT-B null mice at the ages of 6, 16 and 52.weeks. For the action potential recording, the ventricular myocytes of 16 w mice were isolated and recorded by floating microelectrode method. The sodium current was recorded by the patch clamp technique. RT-PCR and Western blot showed the UT-B expression in the heart of wild-type mice. No UT-B transcript and protein was found in UT-B null mice. The ECG recording showed that the P-R interval was significantly prolonged in UT-B null mice ((43.5 ± 4.2., (45.5 ± 6.9) and (43.8 ± 7.6) ms at ages of 6, 16 and 52.weeks) vs wild-type mice ((38.6 ± 2.9), (38.7 ± 5.6) and (38.2.± 7.3) ms, P2.w old). The amplitude of action potential and Vmax decreased significantly in UT-B null mice ((92.17 ± 10.56) and (101.89 ± 9.54) mV/s) vs those in wild-type mice (vs (110.51 ± 10.38) and (109.53 ± 10.64) mV/s, P2..83 ± 11.17) and (195.43 ± 16.41) ms) vs that in wild-type mice ((108.2. ± 10.85) and (171.00 ± 15.53) ms, P2. nA vs that in wild-type mice ((-5.98 ± 1.07) nA, P<0.05). These results provide the first evidence that UT-B deletion causes progressive heart block in mice.

关键词： urea transporter heart block electrocardiogram

From a bound excited state to a singly excited resonanceatoms in plasma environment

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From a bound excited state to a singly excited resonanceatom...

第十六届全国原子与分子物理学术会议

作者： T.N.Chang~1 and T.K.Fang~2.1 department of Physics and Astronomy,university of Southern {2.,los angeles,CA 90089-0484,U.S.A.

By examining in detail the structure of its state wave function,we have recently identified the presence of a singly excited resonance in the continuum for a two-electron *** resonance is different in nature than the ...

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Retroviral Insertional Mutagenesis Screen for Genes Involved in Human Disease Modeling in Zebrafish

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Retroviral Insertional Mutagenesis Screen for Genes Involved...

“基因、进化与生理功能多样性”海内外学术研讨会暨中国生理学会第七届比较生理学学术会议

作者： Ying Zhang~1,Nai-Zhong Zheng~1,Shuo Lin~(1,2.,Bo Zhang~1 1 Key Laboratory of Cell Proliferation and Differentiation,Center of Developmental Biology and Genetics,College of Life Sciences,Peking university,Ministry of Education,Beijing 2.department of Molecular,Cell & Developmental Biology,university of california,los angeles, los angeles,CA 90095-1606,usa

Through retrovirus insertion based mutagenesis screen in zebrafish（Danio reiro） we have obtained several insertions that reside in *** and WDR55 are two candidate genes we conducted further *** encodes a cytokine induced anti-apoptosis protein with a methyltransferase domain, whose ortholog in mice is called Anamorsin. Ciapinl/Anamorsin represents a novel antiapoptotic protein that shares no homology with Bcl-2.and Capase family *** mouse embryos has been reported to be smaller in size compared with wild type littermates, show defects in definitive hemato-poiesis in fetal livers,and begin to die between E12.5 and *** mount in situ hybridization in zebrafish embryos revealed a broad expression pattern of *** ciapinl embryos exhibits edema in pericardial ***55 is a member of WDR-containing protein *** studies have shown that PeBoW complex,which contains a component of WDR12.is required for matura- tion of 60S ribosomal *** is also reported that WDR55 is involved in rRNA processing and cell *** data showed that WDR55 zebrafish embryos begin to die between 7 days post fertilization（dpf） and 10 *** mount in situ hybridization with markers of hematopoietic stem cells c-myb and runxl showed decreased expression in WDR55 *** may imply a function of WDR55 in definitive *** study is interesting because ribosome deficiency has been implicated in several human diseases such as Diamond-Blackfan Anemia that has congenital erythroid *** zebrafish mutants might be useful for modeling and understanding pathogenesis of these human diseases.

关键词： Zebrafish Insertional mutagenesis Retrovirus Cardiovascular development

Zebrafish tyrosine hydroxylase 2.gene encodes tryptophan hydroxylase rather than tyrosine hydroxylase

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Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hyd...

2.12.国发育生物学大会

作者： Guiqi Ren~1,Lu Chen~1,Song Li~1,Hanbing Zhong~1,Shuo Lin~(1,2. 1 Laboratory of Chemical Genomics,School of Chemical Biology and Biotechnology,Peking university Shenzhen Graduate School,Shenzhen,China 2.department of Molecular,Cell and Developmental Biology,university of california los angeles,los angeles, california,United States of America

The primary cause of Parkinson’s disease(PD) is the profound loss of dopaminergic(DA) neurons in the substantia nigra pars *** facilitate the understanding of the underling mechanism of PD,several studies have focused on generating zebrafish PD models,which can recapitulate the characteristic of DA neuron *** zebrafish studies, tyrosine hydroxylase 1(th1) has been frequently used as a marker of DA neurons,although it also labels norepinephrine and epinephrine ***,a homologue of th1,named tyrosine hydroxylase 2.th2. was identified based on the sequence homology and subsequently used as a novel marker of DA *** this study,we present evidence that th2.co-localizes with serotonin in the ventral diencephalon and caudal hypothalamus in zebrafish *** addition, knock-down of th2.reduces the production of serotonin in the corresponding th2.positive *** phenotype can be rescued by both zebrafish th2.and mouse tryptophan hydroxylase(Tph1) mRNA,as well as by the product of tryptophan hydroxylase,***,the purified th2.protein has the tryptophan hydroxylase activity comparable with the mouse Tph1 protein in *** on our in vivo and in vitro studies,we conclude that th2.is a gene coding for tryptophan hydroxylase and should be used as a marker gene of serotonergic neurons. Conclusions:Our data support the idea that th2.is a gene coding for tryptophan hydroxylase and should be used as a marker gene of serotonergic neurons.

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