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2.2. Guideline for the management of hypertension in the elderly population in china

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Journal of Geriatric Cardiology 2024年第6期21卷 589-630页

作者： Hypertension Branch of Chinese Geriatrics Society,beijing Hypertension Association,National Clinical research Center of the Geriatric Diseases Qi HUA Li FAN Zeng-Wu WANG Jing LI 不详 Xuanwu Hospital Capital Medical UniversityBeijingChina Chinese PLA General Hospital BeijingChina Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Preamble Hypertension is one of the most common chronic diseases and the primary risk factor for stroke,myocardial infarction and even cardiovascular *** than half of the elderly population has high blood *** people are a unique group,and strategies for the prevention,diagnosis,evaluation,and treatment of hypertension in elderly individuals differ significantly from those in the general population.

关键词： hypertension prevention diagnosis

Gasdynamic characteristics of toroidal shock and detonation wave converging

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Science china(Physics,Mechanics & Astronomy) 2005年第6期48卷 739-749页

作者： TENG Honghui1,2.& JIANG Zonglin2.1. Key Laboratory of high Temperature Gas Dynamics, Institute of Mechanics, Chinese Academy of Sci- ences, beijing 100080,{2. 2. Graduate University of Chinese Academy of Sciences, beijing 100039,{2. Key Laboratory of high Temperature Gas Dynamics Institute of Mechanics Chinese Academy of Sciences Beijing China Graduate University of Chinese Academy of Sciences Beijing China

The modified CCW relation is applied to analyzing the shock, detonation wave converging and the role of chemical reactions in the process. Results indicate that the shock wave is strengthened faster than the detonation wave in the converging at the same initial Mach number. Euler equations implemented with a detailed chemical reaction model are solved to simulate toroidal shock and detonation wave converging. Gasdynamic characteristics of the converging are investigated, including wave interaction patterns, observable discrepancies and physical phenomena behind them. By comparing wave diffractions, converging processes and pressure evolutions in the focusing area, the different effects of chemical reactions on diffracting and converging processes are discussed and the analytic conclusion is demonstrated through the observation of numerical simulations.

关键词： converging, CCW relation, shock wave, detonation wave.

research progress in the inner surface modification of metal tubes by plasma processing

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Progress in Natural Science:Materials International 2006年第11期16卷 1119-1126页

作者： ZHANG Guling~ 1,2.**, WU Xingfang~1, GU Weichao~2. CHEN Guangliang~2. FENG Wenran~2. NIU Erwu~2. LI Li~2. L Guohua~2. CHEN Huan~2. FAN Songhua~2. LIU Chizi~2.and YANG Size~2.1. School of Material Science and Engineering, University of Science and Technology beijing, beijing 100083,{2. 2. beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, beijing 100080,{2.) School of Material Science and Engineering University of Science and Technology Beijing Beijing 100083 China beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100080 China

The recent progress in inner surface hardening of tubes by plasma processing is summerized. Several techniques of inner surface plasma source ion implantation and deposition are introduced, and their advantages and disadvantages are discussed. The basic principles, technical features and new progress of inner surface plasma source ion implantation methods for metal tubes, which were developed in our laboratory, are described in detail. And perspectives of the future technical development for inner surface ion implantation of tubes are presented.

关键词： PSII metal tubes inner surface surface modification.

Structural stability of infinite-layer CaCuO_2.under high pressure

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Chinese Science Bulletin 2003年第12期48卷 1201-1203页

作者： QIN Xiaomei1,2. HONG Ming1,2. ZHANG Gongmu1,2. MAI Wenjie1,2. LI Fengying1,2. YU Richeng1,2. LIU Jing2.3 & JIN Changqing1,2.1. Institute of Physics, Chinese Academy of Sciences, beijing 100080, china 2. {2. high pressure research Center, beijing 100080, china 3. Institute of high Energy Physics, Chinese Academy of Sciences, {2. 100039, china Correspondence should be addressed to Jin Changqing (e-mail: cqjin@ ***) Institute of Physics Chinese Academy of Sciences Beijing 100080 China beijing high {2. research Center Beijing 100080 China Institute of high Energy Physics Chinese Academy of Sciences Beijing 100039 China

In situ high-pressure energy dispersive X-ray diffraction measurements on polycrystalline powder Ca-CuO2.with an infinite layer structure (IL CaCuO2. have been performed by using diamond anvil cell (DAC) instrument with synchrotron radiation. The results suggest that the crystal structure of IL CaCuO2.is stable under pressure up to 30 GPa at room temperature. According to Birch-Murn- aghan equation of state, assuming pressure derivative 4,=0Bthe bulk modulus B0=181 ?9 GPa is obtained.

关键词： infinite-layer CaCuO2 synchrotron radiation high pressure energy dispersive X-ray diffraction.

Explanation of the mechanism of carcinogenesis and syntheses of anticancer agents with high selectivity

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Science china Chemistry 2006年第1期49卷 44-62页

作者： DAI Qianhuan1,2.1. Center of Chemistry and Bioengineering of Cancer research, beijing Polytechnic University (Now known as beijing Univer-sity of Technology), beijing 10002., china 2. Center of Environmental Sciences, Peking University, beijing 100871, china Center of Chemistry and Bioengineering of Cancer research Beijing Polytechnic University Beijing China Center of Environmental Sciences Peking University Beijing China

In 1979, the mechanism of chemical carcinogenesis, a challenging anddifficult scientific problem pending for a number of years, was explained by Dai Qianhuan. Themechanism named di-region theory predicted that a carcinogen always metabolizes to form a specialbi-functional alky-lating agent. This agent induces cross-linkages between the complementary basepairs in DMA and switches on initial mutageneses in genomes including point and frameshiftmutations. This, in turn, induces further deep mutageneses including the production of variouschimeric chromosomes, deletions and other aberrations found in genomes. In the end this initiatescarcinogenesis of the whole cell through the reverse transcription mechanism after a lengthyincubation period. Recently, this laboratory has verified that physical carcinogenesis, includingthe oncogenesis induced by radiation and asbestos as well as the carcinogenesis induced byendogenous factors such as estrogen or diethyl-stilbestrol switch on carcinogenesis by inducing theformation of cross-linkages between the complementary base pairs in DNA. Di-region theory has nowbeen supported by many experimental observations such as mutational spectra of various *** potential for carcinogenesis, teratogenesis, sterility and mutagenesis lumped together asgenetic toxicity appears to originate almost uniformly from the cross-linking between complementarybases, i.e. malignant cross-linking, which is in accordance with di-region theory. Other forms ofcross-linking between non-complementary bases, benign cross-linkings, show bi-functional alkylationanticancer activity but lack genetic toxicity. The predictable design and synthesis of a highselectivity anticancer agent with high efficacy and low genetic toxicity, a goal long pursued incancer chemotherapy, have been realized for the first time in this laboratory by inhibitingmalignant and heightening benign cross-linking using the principles of di-region theory. A series ofpatented new anticanc

关键词： mechanism of carcinogenesis, di-region theory, minoplatin, selectivity of anticancer agent, cross-linking between DNA bases, anticancer platinum complexes, predictive design of anticancer agent, second generation anticancer agent.

Compression behavior of Zr_(41)Ti_(14)Cu_(12.5)Ni_(10)Be_(2..5) bulk metallic glass up to 2. GPa

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Science china(Physics,Mechanics & Astronomy) 2005年第3期48卷 319-324页

作者： LI Gong 1, 2., ZHAN Zaiji 2., LIU Jing 3 , YUN Jinku 1 , SUN Liling 2., LIU Riping 1 , ZHANG Jun 2.& WANG Wenkui 1, 2.1. Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, china 2. Center for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, beijing 100080, china 3. BSRF, Institute of high Energy Physics, Chinese Academy of Sciences, beijing 100039, china Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao China Center for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing China BSRF Institute of High Energy Physics Chinese Academy of Sciences Beijing China

The compression of a Zr41Ti14Cu12.5Ni10Be2..5 bulk metallic glass (BMG) is investigated at room temperature up to 2. GPa using in-situ high pressure energy dispersive X-ray diffraction with a synchrotron radiation source. The pressure-induced structural relaxation is exhibited. It is found that below about 8 GPa, the existence of excess free volume contributes to the rapid structural relaxation, which gives rise to the rapid volumetric change, and the structural relaxation results in the structural stiffness under higher pressure.

关键词： bulk metallic glass, high pressure, structural relaxation, synchrotron radiation.

Bio-regeneration of p-complexation desulfurization adsorbents

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Science china Chemistry 2005年第6期48卷 538-544页

作者： LI Wangliang1,2. XING Jianmin1, XIONG Xiaochao1,2. SHAN Guobin1,2.& LIU Huizhou1 1. Laboratory of Separation Science and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, beijing 100080, china 2. Graduate School of the Chinese Academy of Sciences,{2. 100039, china Laboratory of Separation Science and Engineering Institute of Process Engineering Chinese Academy of Sciences Beijing China Graduate School of the Chinese Academy of Sciences Beijing China

The coupling of adsorption desulfurization and biodesulfurization is a new approach to produce clean fuels. Sulfur compounds are firstly adsorbed on adsorbents, and then the ad-sorbents are regenerated by microbial conversion. p-Complexation adsorbent, Cu(I)-Y, was ob-tained by ion exchanging Y-type zeolite with Cu2. and then by auto-reduction in helium at 450℃ for 3 h. Dibenzothiophene (DBT) was used as a model compound. The effects of cell concentra-tion, volume of oil phase, the ratio of aqueous phase to adsorbent on DBT desorption by a bac-terium were studied. The amounts of DBT desorbed and 2.HBP produced can be apparently increased with addition of n-octane. BDS activity can be improved by increasing cell concentra-tion and the ratio of water-to-adsorbent. 89% of DBT desorbed from the adsorbents can be converted to 2.HBP within 6 h and almost 100% within 2. h, when the volume ratio of oil-to-water was 1/5 mL/mL, the cell concentration was 60 g·L?1, and the ratio of adsorbent-to-oil was 0.03 g·mL?1. The amount of 2.HBP produced was strongly dependent on the volume ratio of oil-to- water, cell concentration and amount of adsorbent. Adsorption capacity of the regenerated ad-sorbent is 95% that of the fresh one after being desorbed with Pseudomonas delafieldii R-8, washed with n-octane, dried at 100℃ for 2. h and auto-reduced in He.

关键词： adsorption desulfurization p-complexation adsorbents bio-regeneration Pseudomonas delafieldii desorption.

A preliminary study on vegetation-erosion dynamics and its applications

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Science china Earth Sciences 2005年第5期48卷 689-700页

作者： WANG Zhaoyin 1,2., WANG Guangqian 1 , LI Changzhi 1 & WANG Feixin 1 1. Department of Hydraulic Engineering, Tsinghua University, beijing 100084, china 2. International {2. and Training Center on Erosion and Sedimentation, beijing 100084, china Department of Hydraulic Engineering Tsinghua University Beijing China International research and Training Center on Erosion and Sedimentation Beijing China

Vegetation-erosion dynamics is a new interdisciplinary science, studying the laws of evolution of watershed vegetation under the action of various ecological stresses. Introducing a qualitative expression of ecological stresses in this paper, the present authors establish the cou- pled differential equations for the vegetation-erosion process and derive a theoretical solution. The model is applied to the Anjiagou watershed on the Loess Pateau and the Xiaojiang water- shed and its sub-watersheds on the Yunnan Plateau. The calculated results agree well with the vegetation development processes. Abstracted from the differential equations the so-called vegetation-erosion chart is worked out, with which we can predict the development trend of vegetation under no human stresses. It is demonstrated that the erosion control is important for vegetation development and reforestation must be a long-term strategy. On the Yunnan Plateau with relatively high precipitation and temperature, vegetation can be greatly improved if erosion is controlled. On the dry and cold Loess Pateau suffering from high rate of soil erosion, however, vegetation can effectively control erosion but erosion reduction exhibits low effectiveness on vegetation development. Vegetation in the area is not stable and management is always needed to maintain the vegetation.

关键词： vegetation-erosion dynamics, human activities, coupled differential equations, erosion control, vigor ofvegetation.

Approaches to improving critical current density of YBCO superconducting thick films deposited by electrophoresis

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Science china(Physics,Mechanics & Astronomy) 2004年第2期47卷 165-172页

作者： ZHU Yabin1,2. ZHOU Yueliang2. LIU Zhen2. WANG Shufang2. CHEN Zhenghao2. L?Huibin2. YANG Guozhen2. XIAO Ling3, REN Hongtao3, JIAO Yulei3 & ZHENG Minghui3 1. Department of Physics, College of Science, beijing Jiaotong University, beijing 100044,{2. 2. Laboratory of Optical Physics, Institute of Physics and Center for Condensed Matter Physics, Chinese Academy of Sciences, beijing 100080,{2. 3. General research Institute for Nonferrous Metals, beijing 100088,{2. Correspondence should be addressed to Zhu Yabin (email: ybzhu@***) Department of Physics College of Science Beijing Jiaotong University Beijing China Laboratory of Optical Physics Institute of Physics and Center for Condensed Matter Physics Chinese Academy of Sciences Beijing China General research Institute for Nonferrous Metals Beijing China

Fabrication of YBCO superconducting thick films by electrophoresis has been widely reported. However, the value of critical current density (J c) is far from what the practical application requires. The superconducting thick films are obtained using top-seeded melt growth method with different proportional Y2.aCuO5 (Y2.1) addition. high-pressure oxygen has been used in the annealing process to improve the uniformity of the oxygen content in the superconducting thick films. When 40mol% Y2.1 powder is added to the YBa2.u3O7–5 (Y12.) powder,J c for the superconducting thick film by approaches described above reaches 7.008×103 A/cm2.(77 K, 0 T), which is greater than the value ever reported.

关键词： YBCO thick films, electrophoretic deposition, melt-textured.