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检索条件"作者=2 State Key Laboratory of Molecular biology,Institute of Biochemistry and cell biology,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China"
142 条 记 录,以下是131-140 订阅
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Efalizumab binding to the LFA-1 αL I domain blocks ICAM-1 binding via steric hindrance
Efalizumab binding to the LFA-1 αL I domain blocks ICAM-1 b...
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第十一次中国生物物理学术大会暨第九届全国会员代表大会
作者: Sheng Li a,1 ,Hao Wang b,1 ,Baozhen Peng a ,Meilan Zhang a ,Daipong Zhang b ,Sheng Hou b ,Yajun Guo b,2 ,and Jianping Ding a,2 astate key laboratory of molecular biology and Research Center for Structural biology,institute of biochemistry and cell biology,shanghai institutes for biological sciences,chinese academy of sciences,320 Yue-Yang Road,shanghai 200031,china b International Joint Cancer institute,Second Military Medical University,800 Xiang-Yin Road,shanghai 200433,china
<正>LFA-1,a member of 2 integrin family,plays important roles in immune cell adhesion,trafficking and ***-1 is present on all leukocytes and is a therapeutic target for
来源: cnki会议 评论
Suppression of hLRH-1 mediated by a DNA vector-based RNA interference results in cell cycle arrest and induction of apoptosis in hepatocellular carcinoma cell BEL-7402
Suppression of hLRH-1 mediated by a DNA vector-based RNA int...
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第四届全国RNA进展研讨会
作者: Shuiliang Wang, Fenghua Lan, Lianghu Huang, Lihong Dong, Zhongyong Zhu, Zonghai Li, Youhua Xie and Jiliang Fu Center for laboratory Medicine, Fuzhou General Hospital, Fuzhou , Fujian 350025, P R china state key laboratory of Oncogenes and Related Genes, shanghai Cancer institute, shanghai 200032, P R china institute of biochemistry and cell biology, shanghai institutes for biological sciences, chinese academy of sciences, shanghai 200031, P R china Department of Medical and Life Science, Tongji University, shanghai 200092, P R china
LRH-1 is an orphan nuclear receptor predominantly expressed in tissues of endodermal origin, where it controls development and cholesterol homeostasis (1). In a previous study we found that the gene expression profile...
来源: cnki会议 评论
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition
Slit-2 repels the migration of olfactory ensheathing cells b...
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中国神经科学学会第九届全国学术会议暨第五次会员代表大会
作者: Zhi-Hui HUANG~(1,2,4),Ying WANG~(1,2,4),Zhi-Da SU~1,Jian-Guo GENG~5,Yi-Zhang CHEN~(1,4),Xiao-Bing YUAN~(3,*), Cheng HE~(1,4,*) 1 institute of Neuroscience and key laboratory of molecular Neurobiology of Ministry of Education,Neuroscience Research Center of Changzheng Hospital,Second Military Medical University,shanghai 200433,china 2 institute of Hypoxia Medicine,Wenzhou Medical College,Wenzhou,Zhejiang 325035,china 3 institute of Neuroscience and state key laboratory of Neuroscience,chinese academy of sciences,shanghai 200031, china 4 institute of Neuroscience,Zhejiang University School of Medicine,Hangzhou,Zhejiang 310058,china 5 institute of biochemistry and cell biology,shanghai institutes for biological sciences,chinese academy of sciences, shanghai 200031,china
Olfactory ensheathing cells(OECs) migrate from the olfactory epithelium towards the olfactory bulb during ***,the guidance mechanism for OEC migration remains a *** we show that migrating OECs expressed the receptor o... 详细信息
来源: cnki会议 评论
Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells Running title: Hepatocarcinogenesis and PEG10 activation
Androgen activates PEG10 to promote carcinogenesis in hepati...
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中国免疫学会第五届全国代表大会暨学术会议
作者: Xiong Jie, Li Chaoqun, Yang Dehua, Shi Yi, Hu Chunsong, Gong Feili, Jin Boquan, Jin Youxin, Tan Jinquan (Department of Immunology, and laboratory of Allergy and Clinical Immunology, institute of Allergy and Immune-related Diseases and Medical Research Center, Wuhan University School of Medicine, Wuhan, 430071 The state key laboratory of molecular biology, institute of biochemistry and cell biology, shanghai institutes for biological sciences, chinese academy of Science, shanghai, 200031 Department of Infectious Diseases, Ruijin Hospital, shanghai Second Medical University. shanghai, 200025 College of Life sciences, South china Normal University, Guangzhou, 510631 Department of Immunology, College of Basic Medical sciences, Anhui Medical University, Hefei 230032 Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan Department of Immunology, Fourth Military Medical University, Xian, P. R. china
The molecular mechanisms of hepatocellular carcinoma (HCC) with a striking higher prevalence in male remain to be fully elucidated. We here report the differentially expression of androgen receptor (AR) in different H...
来源: cnki会议 评论
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition
Slit-2 repels the migration of olfactory ensheathing cells b...
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“细胞活动 生命活力”——中国细胞生物学学会全体会员代表大会暨第十二次学术大会
作者: Zhi-hui Huang~(1,3,4),Ying Wang~(1,3,4),Zhi-da Su~1,Jian-guo Geng~5,Yi-zhang Chen~(1,4),Xiao-bing Yuan~2,Cheng He~(1,4) 1.institute of Hypoxia Medicine,Wenzhou Medical College,Wenzhou,Zhejiang 325035,china 2.institute of Neuroscience and key laboratory of molecular Neurobiology of Ministry of Education,Neurosciencc Research Center of Changzheng Hospital,Second Military Medical University,shanghai 200433,china. 3.institute of Neuroscience and state key laboratory of Neuroscience,chinese academy of sciences,shanghai 200031,china. 4.institute of Neurosciencc,Zhejiang University School of Medicine,Hangzhou,Zhejiang 310058,china. 5.institute of biochemistry and cell biology,shanghai institutes for biological sciences,chinese academy of sciences,shanghai 200031, china.
Olfactory ensheathing cells(OECs) migrate from the olfactory epithelium towards the olfactory bulb during ***,the guidance mechanism for OEC migration remains a *** we show that migrating OECs expressed the receptor o... 详细信息
来源: cnki会议 评论
Efalizumab binding to the LFA-1 α_L I domain blocks ICAM-1 binding via steric hindrance
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生物物理学报 2009年 第S1期25卷 342-342页
作者: Sheng Lia,1, Hao Wangb,1, Baozhen Penga, Meilan Zhanga, Daipong Zhangb, Sheng Houb, Yajun Guob,2, and Jianping Dinga,2 astate key laboratory of molecular biology and Research Center for Structural biology, institute of biochemistry and cell biology, shanghai institutes for biological sciences, chinese academy of sciences, 320 Yue-Yang Road, shanghai 200031, china bInternational Joint Cancer institute, Second Military Medical University, 800 Xiang-Yin Road, shanghai 200433, china 1These authors contributed equally to this work.
LFA-1, a member of 2 integrin family, plays important roles in immune cell adhesion, trafficking and activation. LFA-1 is present on all leukocytes and is a therapeutic target
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
RNA-interference-based functional research on rat epididymis-specific gene 16 and human paternally expressed gene PEG10 and the therapeutic applications of RNA interference in HBV,SARS,liver cancer,liver fibrosis and keloid fibroblast
RNA-interference-based functional research on rat epididymis...
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第四届全国RNA进展研讨会
作者: Shi Y, Xiong J, Zhou XM, Yang DH, Li GM, Gao ZY and Jin YX The state key laboratory of molecular biology, institute of biochemistry and cell biology, shanghai institutes for biological sciences, chinese academy of Science, shanghai 200031, china. Department of Immunology, Wuhan University School of Medicine, Wuhan, Hubei 430071, china. institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, china.College of Life Science, South china Normal University, Guangzhou 510631, china. Department of Gastroenterology, Xinhua Hospital, shanghai Second Medical University, shanghai 200092, china. Department of Plastic Surgery, Changzheng Hospital, Second Military Medical University, shanghai 200003, china.
RNA interference or RNAi is a powerful cellular mechanism of eukaryotic gene regulation in which a short sequence of double-stranded RNA (dsRNA) specifically down-regulates expression of the associated gene. In mammal...
来源: cnki会议 评论
Different neurotropic pathogens elicit neurotoxic CCR9-or neurosupportive CXCR3-expressing microgli
Different neurotropic pathogens elicit neurotoxic CCR9-or ne...
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中国免疫学会第五届全国代表大会暨学术会议
作者: Zhou Gang, He Yu-ling, He Li, Xie Luo-kun , Xiong Jie, Lei Hao, Wei Li, Hu Chun-song, Liu Jun-yan, Jian Ming-shen, Jin You-xin, Gong Fei-li, Jin Bo-quan, Tan Jin-quan Departments of Immunology Parasitology, institute of Allergy and Immune-related Diseases Laboratories of Neuroscience Allergy and Clinical Immunology, Center for Medical Research, Wuhan University School of Medicine, Wuhan The state key laboratory of molecular biology and Neuroscience, institute of biochemistry and cell biology, shanghai institutes for biological sciences, chinese academy of Science, shanghai The state key laboratory of Magnetic Resonance and Atomic and molecular Physics, institute of Physics and Mathematics, chinese academy of sciences, Wuhan key laboratory of Colloid, Interface Science and Chemical Thermodynamics, institute of Chemistry, chinese academy of sciences, Beijing Department of Immunology, College of Basic Medical sciences, Anhui Medical University, Hefei Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan Department of Immunology, Fourth Military Medical University, Xian, P. R. china
What mechanism to determine microglia accomplishing destructive or constructive role in CNS remains nebulous. We report here that intracranial priming and re-challenging with T. gondii in mice elicit neurotoxic CCR9+ ...
来源: cnki会议 评论
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
Acetylation Targets the M2 Isoform of Pyruvate Kinase for De...
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“细胞活动 生命活力”——中国细胞生物学学会全体会员代表大会暨第十二次学术大会
作者: Lei Lv~(1,3,4),Dong Li~(5#),Di Zhao~(3,4#),Ruiting Lin~(3,4),Yajing Chu~6,Heng Zhang~(1,3,4),Zhengyu Zha~3,Ying Liu~2,Zi Li~7, Yanping Xu~(3,4),Gang Wang~6,Yiran Huang~5,Yue Xiong~(3,4,8),Kun-Liang Guan~(1,3,9)and Qun-Ying Lei~(1,3) 1.key laboratory of molecular Medicine,Ministry of Education,Department of biochemistry and molecular biology, 2.Department of Pathology,shanghai Medical College, 3.molecular and cell biology Lab,institutes of Biomedical sciences, 4.School of Life Science,Fudan University,shanghai 200032,china, 5.Department of Urology,Ren Ji Hospital,shanghai Jiao Tong University,1630 Dong Fang Road,shanghai 200127,china, 6.institute of biochemistry and cell biology, 7.institute for Nutritional sciences,shanghai institutes for biological sciences,chinese academy of sciences,shanghai 200031,china, 8.Department of biochemistry and Biophysics,Lineberger Comprehensive Cancer Center,University of North Carolina at Chapel Hill,North Carolina 27599,USA, 9.Department of Pharmacology and Moores Cancer Center,University of California at San Diego,La Jolla,CA 92093-0815,USA.
Most tumor cells take up more glucose than normal cells but metabolize glucose via glycolysis even in the presence of normal level of oxygen,a phenomenon known as Warburg *** cells commonly express the embryonic M2 is... 详细信息
来源: cnki会议 评论
高密度发酵制备重组人OCIF活性域多肽融合蛋白
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微生物学通报 2004年 第6期31卷 53-56页
作者: 张兴群 王梁华 焦炳华 袁勤生 华东理工大学生物反应器国家重点实验室 第二军医大学基础医学部生物化学和分子生物学教研室 上海200433
以补料 分批发酵方式在 3 7L发酵罐上实现了人破骨细胞形成抑制因子活性域多肽(OCIFAD)的高密度发酵融合表达。通过参数控制。发酵液最终OD6 0 0 达 1 2 5 (相当于 35g湿菌体 L) ,表达量占菌体总蛋白 40 %左右 ,含量超过 0 6g L ,并且... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论