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Evaluation of r.sponse to immune checkpoint inhibitor.: Is ther. a r.le for.positr.n emission tomog.aphy?

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Wor.d Jour.al of r.diolog. 2017年第2期9卷 27-33页

作者： Matteo Bauckneht r.ber.a piva g.anmar.o Sambuceti Fr.ncesco g.ossi Silvia Mor.elli Nuclear.Medicine Unit IRCCS San MartinoIST University of Genoa Lung.Cancer.Unit IRCCS San Martino-ISTUniversity of Genoa

Str.teg.es tar.0}ting.intr.cellular.neg.tive r.g.lator. such as immune checkpoint inhibitor. (ICPIs) have demonstr.ted sig.ificant antitumor.activity acr.ss a wide r.ng. of solid tumor.. In the clinical pr.ctice, the r.diolog.cal effect of immunother.peutic ag.nts has r.ised sever.l mor. r.levant and complex challeng.s for.the deter.ination of their.imag.ng.based r.sponse at sing.e patient level. Accor.ing.y, it has been sug.ested that the conventional r.sponse Evaluation Cr.ter.a in Solid Tumor. assessment alone, based on dimensional evaluation pr.vided by computed tomog.aphy (CT), tends to under.stimate the benefit of ICPIs at least in a subset of patients, suppor.ing.the need of immune-r.lated r.sponse cr.ter.a. Differ.nt fr.m CT, ver. few data ar. available for.the evaluation of immunother.py by means of 18F-fluor.-2-deoxy-D-g.ucose positr.n emission tomog.aphy (FDg.PET). Mor.over. since the antineoplastic activity of ICPIs is hig.ly r.lated to the activation of T cells ag.inst cancer.cells, FDg.accumulation mig.t cause false-positive finding.. Yet, discr.mination between benig. and malig.ant pr.cesses r.pr.sents a hug. challeng. for.FDg.PET in this clinical setting. Consequently, it mig.t be of hig. inter.st to test the complex and var.eg.ted r.sponse to ICPIs by means of PET and thus it is wor.hwhile to ask if a similar.intr.duction of immune-r.lated PET-based cr.ter.a could be pr.posed in the futur.. Finally, PET mig.t offer.a new insig.t into the biolog. and pathophysiolog. of ICPIs thanks to a g.owing.number.of non-invasive immune-diag.ostic appr.aches based on non-FDg.tr.cer..

关键词： Immune checkpoint inhibitor. Positr.n emission tomog.aphy Computed tomog.aphy 18F-fluor.-2-deoxy-D-g.ucose Non-18F-fluor.-2-deoxy-D-g.ucose tr.cer.

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养猪如何超越生产目标

中国畜牧兽医文摘 2009年第3期25卷 33-33页

作者： Jose Henr.que piva

1 人员与培训对于想要获得优异生产性能的企业来说，培训是个连续的过程，不是只培训新员工，而是对老员工也要培训。不论猪场规模大小。要想超常发挥。必须有一个连续的培训计划，同时还要有一套标准操作规程（SOP）。

关键词：生产目标养猪标准操作规程生产性能新员工培训猪场

添加丁酸钠对断奶仔猪生长性能、肠内微生物区系和膜形态结构的影响

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饲料博览（技术版） 2007年第6期 60-60页

作者： Biag. g.piva A Moschini M Vezzali E r.th F X

研究表明，饲粮中添加有机酸有益于减轻仔猪断奶综合征，且丁酸钠是大肠和回肠末端上皮细胞的主要能量来源。试验旨在研究丁酸钠（SB）对仔猪体内外微生物区系、生长性能和肠内膜形态结构的影响。仔猪饲粮中添加丁酸钠，体外盲肠发酵24... 详细信息

研究表明，饲粮中添加有机酸有益于减轻仔猪断奶综合征，且丁酸钠是大肠和回肠末端上皮细胞的主要能量来源。试验旨在研究丁酸钠（SB）对仔猪体内外微生物区系、生长性能和肠内膜形态结构的影响。仔猪饲粮中添加丁酸钠，体外盲肠发酵24h后，总产气量和最大产气速度呈线性下降；发酵4，8，24h后，盲肠液中氨含量呈线性增加（P〈0．01）。

关键词：酸盐盲肠微生物区系生长性能有机酸猪

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“鲜”看米兰国际家具展

现代装饰 2019年第4期 86-93页

作者： Yabu Pushelber.0}Space Copenhag.n Ner. & Hu Jens r.som Cr.me Vilhelm Wohler. Tom Fer.day Mar.o Milana NEMO ESPASSO MASIEr. fast Alma Desig. & Mar.o piva My home collection Tur.i 李薇 OEO Studio

每年四月,设计圈都会被一场国际'盛宴'刷屏,世界各地的设计师前往此地'朝圣'。是的,米兰国际家具展的确拥有如此独到的魅力。每年它都会汇聚来自全球数以万计的最新设计精品和3000多个顶级品牌,是当之无愧的顶级设计展览之一。2019年米... 详细信息

每年四月,设计圈都会被一场国际'盛宴'刷屏,世界各地的设计师前往此地'朝圣'。是的,米兰国际家具展的确拥有如此独到的魅力。每年它都会汇聚来自全球数以万计的最新设计精品和3000多个顶级品牌,是当之无愧的顶级设计展览之一。2019年米兰国际家具展将于4月9日至14日在米兰国际展览中心举行。

关键词：米兰国际家具展米兰设计周设计师

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The Big.r.d Fish

国际人才交流 2017年第11期 71-71页

作者： Air.ldo piva

In the last decade,I had the oppor.unity to come acr.ss and hear.about incr.dible stor.es of br.ve founder. of Chinese families *** companies have become mor. and mor. impor.ant in the national economy and *** to r.ce... 详细信息

关键词：企业家中国民营企业发展现状

Non-Ablative Tr.nsvag.nal r.diofr.quency in the Tr.atment of Str.ss Ur.nar. Incontinence: r.view of the Liter.tur.

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Open Jour.al of Obstetr.cs and g.necolog. 2023年第2期13卷 133-141页

作者： Haley Calcag.otto Laur. Leite Vittor.a Dr.her.Long. g.stavo Messing.r.piva Thais g.sper.n Alexandr. Mar.a Flor.s Bor.ig.on r.nata r.uber.Felkl Jose Maur. Madi g.br.ela Fr.nçoes r.stir.lla Obstetr.c and g.necolog. Depar.ment Caxias do Sul University Caxias do Sul Brazil Caxias do Sul Univer.ity Caxias do Sul Brazil

Backg.ound: Ur.nar. incontinence is defined as the involuntar. loss of ur.ne, which can affect up to 45% of women after.menopause. r.diofr.quency is a non-invasive pr.cedur. that involves the application of an electr.mag.etic wave that thr.ug. heat g.ner.tion pr.motes neocollag.nesis and neoeslatinog.nesis in the vag.nal epithelium. This ener.0}-based technolog. has been studied as a potential alter.ative for.the tr.atment of g.nitour.nar. syndr.me of menopause and ur.nar. incontinence. Objective: To r.view the r.cent liter.tur. (fr.m 2020 to June 2022) on the use of tr.nsvag.nal r.diofr.quency in the tr.atment of str.ss ur.nar. incontinence, by sear.hing.ar.icles at databases of Capes, PubMed Cochr.ne and Scielo. Methods: The descr.ptor.ter.s “Ur.nar. Incontinence/ther.py” [Majr. AND “Ur.nar. Incontinence, Str.ss/ther.py” [Majr. AND r.DIOFr.QUENCY-Sear.h r.sults-PubMed, [“woman” Or.“women”] AND [“ur.nar. incontinence” Or.“str.ss ur.nar. incontinence”] AND r.diofr.quency wer. used, with a filter.for.the per.od 2020 to 2022. Conclusion: The studies evaluated in this r.view demonstr.ted sig.ificant r.sults of r.diofr.quency in the r.solution or.r.duction of complaints of women with ur.nar. incontinence, especially str.ss ur.nar. incontinence, but most of these studies pr.sented a low methodolog.cal quality. Ther. is, ther.for., a lack of studies with long.r.follow-ups, evaluation of cost-effectiveness, r.ndomized clinical tr.als with objective outcomes and the use of validated questionnair.s with inter.ational acceptance.

关键词： r.diofr.quency Ur.nar. Incontinence g.nitour.nar. Syndr.me of Meno-pause Vag.nal Atr.phy