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Effects of Electroacupuncture on Expressions of Angiogenesis Factors and Anti-angiogenesis Factors in Brain of Experimental Cerebral Ischemic Rats after Reperfusion

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Journal of Traditional Chinese Medicine 2008年第3期28卷 217-222页

作者：马璟曦罗勇王友京 The First Affiliated Hospital Chongqing University of Medical Sciences

Objective:To explore the mechanism of electroacupuncture(EA) in improving ischemic ***:The Wistar rat model of focal cerebral ischemia-reperfusion was prepared by the thread embolism *** rats were randomly divided into a normal group,a model group,and an EA *** was given at bilateral "Hegu"(LI 4) in rats of the EA *** of the vascular endothelial growth factor(VEGF) mRNA was detected with hybridization in situ,and expressions of the angiogenin-1(Ang-1) and endostatin proteins were detected with the immunohistochemical ***:As compared with the normal group,the expressions of VEGF mRNA,Ang-1 protein and endostatin protein significantly increased in the model group(all P<0.05);and when compared with the model group,the EA group showed even more significant increase in expressions of the VEGF mRNA and Ang-1 protein(both P<0.05),but with an obvious decline in the increase of expression of endostatin protein(P<0.05).Conclusions:EA can promote angiogenesis in brain of experimental cerebral ischemic rats after reperfusion probably through up-regulating the expression of angiogenesis factors and down-regulating the expression of anti-angiogenesis factors.

关键词：电针刺治疗实验医学

实验性脊髓损伤后针剌治疗的有益作用：行为的,形态的...

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国外医学（中医中药分册） 1991年第3期13卷 34-36页

作者： Poli.,MJ 王友京

Advances of Studies on Mechanisms of Drugs for Activating Blood Circulation and Removing Blood Stasis in Treatment of Primary Liver Cancer

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Journal of Traditional Chinese Medicine 2005年第4期25卷 304-309页

作者：任荣政鞠立霞陈喆王友京 Hemopathy Department Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Tianshan Hospital of Traditional Chinese Medicine Changning District Changhai Hospital

Primary liver cancer is mainly characterized by the mass in hypochondriac region, stabbing pain at a fixative region, tenderness, dim complexion,vascular spider, vein exposure, livid tongue,ecchymosis, taut and uneven pulse and other symptoms of blood stasis. Experimental studies have found that the patient with liver cancer is often accompanied with disturbance of microcirculation,increase of blood viscosity and high blood agglutinative state. Therefore, activating blood circulation to remove blood stasis is clinically an important therapy for primary liver cancer. A great number of studies on the mechanisms have been carried out in China and other countries. The follow is a review about the mechanisms.

关键词：血液循环原发性肝癌中医治疗水蛭

用间接“双指O—环试验成像技术”在人尸体作胃的像...

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国外医学（中医中药分册） 1990年第3期12卷 44-45页

作者： Omura.,Y 王友京

Clinical Observation on 100 Cases of Postoperative Pain of Anal-Intestinal Diseases Treated with Vitamine K Blocking at Changqiang Point

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Journal of Traditional Chinese Medicine 2002年第4期22卷 280-281页

作者：王为张景云王友京 Xuzhou Municipal Hospital of TCM Xuzhou 221003Jiangsu Province

　　Since the latter half of 1996, we have used vitamine K blocking at Changqiang (GV 1) for relieving the postoperative pain of anal fissure with satisfactory results. A report follows.……

关键词： In Clinical Observation on 100 Cases of Postoperative Pain of Anal-Intestinal Diseases Treated with Vitamine K Blocking at Changqiang Point

Regulative Actions of the Chinese Drugs for Tonifying the Kidney on Gene Expression of the Hypothalamic GnRH,Pituitary FSH,LH and Osteoblastic BGP

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Journal of Traditional Chinese Medicine 2005年第1期25卷 58-61,页

作者：蔡德培张炜王友京 Pediatric Hospital Affiliated to Shanghai Medical University Shanghai 200032China Shanghai Pasaike Bioengineering Institute

It is found that the drugs for nourishing yin to reduce pathogenic fire can significantly down-regulate, and the drags for tonifying the kidney to replenish essence can up-regulate mRNA expression of the hypothalamic GnRH, pituitary FSH, LH and osteoblastic BGP, indicating that the Chinese drugs for tonifying the kidney can regulate gene expression of the hypothalamic GnRH, pituitary FSH, LH, and osteoblastic BGP, which is possibly one of the main mechanisms of the Chinese drug for tonifying the kidney, regulating ephebic development process and improving skeletal development in sexual precocity children.

关键词：中医药疗法基因表达下丘脑垂体造骨细胞小儿性早熟骨骼发育

Experimental Study on Acupuncture Activating the Gonadotropin-releasing Hormone Neurons in Hypothalamus

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Journal of Traditional Chinese Medicine 2010年第1期30卷 30-39页

作者：王少军朱兵任晓暄谭连红王友京 Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences

Objective:To probe into the most effective site,extra-ordinary point,acupoint and channel for regulating reproductive endocrine function by means of the study on acupuncture activating the gonadotropin-releasing hormone neurons(GnRH) in ***:Female SD rats of reproductive age were used,and the in vivo study on GnRH neurons in hypothalamus was made with mimic sexual stimulation and feedback *** neuron-activating effects of the acupoints on the channels pertaining to the zang-and fu-organs related with reproductive endocrine and the extra-ordinary points in different regions were studied using the discharge of the neuron as index,and then the neurons were labeled with horseradish peroxidase(HRP) .Results:Acupuncture was given at two acupoints each on the three yin channels of foot,the three yang channels of foot,the Conception Vessel and the Governor *** order of the mean increasing percentage in the hypothalamic GnRH neuron electric activity was:the Gallbladder Channel>the Spleen Channel>the Stomach Channel/the Bladder Channel/the Conception Vessel>the Liver Channel>the Kidney Channel>the Governor Vessel;for different acupoints,it was:Guanyuan(CV 4) >Sanyinjiao(SP 6) >Zusanli(ST 36) >Daimai(GB 26) /Yanglingquan(GB 34) >Shenshu(BL 23) >Weizhong(BL 40) >Yaoyangguan(GV 3) /Liangmen(ST 21) /Fujie(SP 14) >Qimen(LR 14) /Yingu(KI 10) >Tangzhong(CV 17) /Zhiyang(GV 9) ;for different positions,it was:the lower abdominal part/the lower limb part>the thoracodorsal part;for the extra-ordinary points,it was:Zigong(EX-CA1) >Dannang(EX-LE6) /Yaoyan(EX-B7) >Baichongwo(EX-LE3) /Qianzheng>Jingbi/Bizhong/Taiyang(EX-HN5) >Erbai(EX-UE2) /Dingchun;and for the distribution sites of the extra-ordinary points:lower abdominal region>the lower limb region>the craniofacial region>the upper limb region/the thoracodorsal ***:For regulating the reproductive endocrine function,the acupoints located at the same neural segment with the reproductive organ

关键词：中医学针刺疗法实验学习荷尔蒙神经细胞

Sixty-seven Cases of Abnormal Movement of the Cardiac Apex Treated with Bu Xin Tang

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Journal of Traditional Chinese Medicine 2002年第3期22卷 174-177页

作者：王平耿世钊王友京 TCM Dept.of Anzhen Hospital Attached to Beijing Capital Medical UniversityBeijing 100029

　　Bu Xin Tang (heart-reinforcement decoction) was used to treat 67 cases of abnormal movement of the cardiac apex based on differentiation of symptoms and signs. The results showed that, in most patients, there were remarkable improvement notonly for the symptoms but also for the abnormal movement of the cardiac apex. The cured plus remarkably effective rate was 87%, suggesting that it can postponeor prevent coronary heart attacks for the patient of prophase coronary heart disease.……

关键词： Sixty-seven Cases of Abnormal Movement of the Cardiac Apex Treated with Bu Xin Tang

134 针刺戒毒——1500例病人的临床观察

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国际中医中药杂志 1989年第3期11卷 39-41页

作者：王友京(译者) 本刊编辑部(其他)