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Current Zoology 2023年第4期69卷 418-425页

作者： ELTE Eötvös Loránd University Hajriz Berisha Gergely Horváth žig. fišer Gergely Balázs Cene fišer Gábor Herczeg Author Notes Behavioural Ecology Group Department of Systematic Zoology and EcologyBiological InstituteELTE Eötvös Loránd UniversityPázmány Péter sétány 1/CBudapestHungary H-1117 ELKH-ELTE-MTM Integrative Ecology Research Group Pázmány Péter sétány 1/CBudapestHungary H-1117 Department of Biology Biotechnical FacultyUniversity of LjubljanaJamnikarjeva 1011000 LjubljanaSlovenia

Populations experiencing neglig.ble predation pressure are expected to evolve hig.er behavioral ***,when sexes have different expected benefits from hig. activity,the adaptive shift is expected to be ***,we compared movement activity of one cave(lack of predation)and three adjacent surface(hig. and diverse predation)populations of Asellus aquaticus,a freshwater isopod known for its independent colonization of several caves across *** predicted 1)hig.er activity in cave than in surface populations,with 2)the difference being more pronounced in males as they are known for active mate searching behavior,while females are *** was assessed both in the presence and absence of *** results supported both predictions:movement activity was hig.er in the cave than in the surface populations,particularly in *** predation pressure in the cave-adapted population is most likely the main selective factor behind increased behavioral activity,but we also showed that the extent of increase is sex-specific.

关键词： adaptation cave colonization movement activity predator-free environment

Metal-organic frameworks (MOFs) in aqueous batteries (ABs):unlocking potential through innovative materials desig.

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Science China Chemistry 2025年

作者： Bo Han erhai Hu Bei-er Jia Ziyang Liu Shuen Tso Afriyanti Sumboja Ivandini T.Anggraningrum Anne Zulfia Syahrial Qingyu Yan SCARCE Laboratory Energy Research Institute NTU (ERIN) Nanyang Technological University School of Materials Science and Engineering Nanyang Technological University Material Science and Engineering Research Group Faculty of Mechanical and Aerospace Engineering Institut Teknologi Bandung Department of Chemistry University of Indonesia Metallurgical & Materials Engineering Department Fakultas Teknik Universitas Indonesia

Metal-organic frameworks (MOFs) represent a revolutionary class of materials in the field of energy storage,particularly for aqueous batteries (ABs).Distinguished by their large surface area,tuneable porosity,and adaptable chemical activity,MOFs offer sig.ificant advantages over conventional materials in battery *** article provides a thorough analysis of the crucial role that MOFs play in improving the efficiency of *** includes a concise review of the current research progress,emphasizing the fundamental processes by which MOFs enhance electrochemical ***,the review examines the synthesis and desig. strategies for the structure of MOFs to maximize ion transport,improve conductivity,and enhance *** structural advantages,chemical versatility,stability,durability and functionalization potential of MOFs are comprehensively ***,we explore the distinct advantages of MOFs in overcoming common challenges encountered in ABs,such as declining capacity,inadequate cycling stability,and limited energy *** paper also hig.lig.ts the future research directions needed to fully harness their *** goal is to develop a fundamental understanding and stimulate further progress in the use of MOFs for advanced energy storage solutions.

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Post-gastrectomy patients need to be followed up for 20-30 years

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World Journal of Gastroenterology 2000年第1期6卷 45-48页

作者： Tovey fi Hobsley M Department of Surgery Royal Free and University College Medical SchoolLondon 67-73 Riding House StreetLondon W1P 7LDUK

AIM:To investig.te the incidence and management of nutritional deficiencies following a ***:A gastrectomy population of 227 patients in London was followed up for 30 years after operation to detect and treat nutritional ***:By the end of the first decade iron deficiency was the commonest problem. Vitamin B(12) deficiency became more important in the second decade. During the third decade both reached equal prevalence, being found in some 90% of the female and 70% of the male residual population. Vitamin D deficiency was a lesser problem, reaching its climax in the second decade. Overall, all women fared worse than ***:The importance of long-term follow-up of gastrectomy patients for iron, Vitamin B(12) and Vitamin D deficiencies is emphasised.

关键词： Subject headings gastrectomy nutrition iron vitamin B_(12) vitamin D

一种基于柱面镜聚焦系统的高灵敏度全谱光谱仪

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光谱学与光谱分析 2025年第1期45卷 222-230页

作者：陈吉文陈作儿赵迎北方工业大学电气与控制工程学院北京100144

很多元素的最灵敏谱线主要分布在紫外波段。一些常被作为检测对象的重要元素,例如C、P和S,其谱线甚至位于200 nm以下的真空紫外波段。然而真空紫外波段内的辐射极易受空气吸收而无法在空气中传输。因此为了适用于紫外波段各谱线的检测,... 详细信息

很多元素的最灵敏谱线主要分布在紫外波段。一些常被作为检测对象的重要元素,例如C、P和S,其谱线甚至位于200 nm以下的真空紫外波段。然而真空紫外波段内的辐射极易受空气吸收而无法在空气中传输。因此为了适用于紫外波段各谱线的检测,常使用光程短、系统精简的罗兰圆光学系统作为光谱仪的色散系统,并且在进行检测分析时,还需对设备腔体内部建立相对真空的环境进行实验,进而减小实验环境对真空紫外波段内各谱线强度的削弱作用。然而即使在该条件下,P和S这两种元素在真空紫外波段的谱线灵敏度仍然较弱。为此为了实现真空紫外波段范围内的高灵敏度,本研究在距离像面前30 mm处位置设计了一个柱面镜聚焦系统。其采用了材料为CaF_(2)、中心厚度为5 mm以及弧矢面曲率半径为22.06 mm的柱面镜作为核心部件。并利用仿真软件Zemax对设计的光学系统进行仿真与优化,以及从非序列模式下的辐射照度仿真结果可知,柱面镜聚焦系统在几乎不影响分辨率的情况下对各波长成像灵敏度有较大的提升。最后以中低合金钢为检测样品,使用电火花激发光源对样品中各元素在紫外波段内的各谱线进行激发,进而验证光谱仪的各项性能:通过一次拟合、参比拟合以及二次拟合,建立每个元素谱峰强度和实际含量之间的数学模型,并算得各元素的拟合优度R^(2)均在0.99以上;柱面镜聚焦系统显著提高了设备在真空紫外波段的灵敏度,响应提高了1倍以上。实验结果表明,柱面镜聚焦系统的设计方法对于提升罗兰圆色散系统的灵敏度具有一定的参考价值。

关键词：紫外光谱罗兰圆光学系统柱面镜灵敏度拟合优度

The phytoconstituents and the comparative effects of aqueous extract of Irvingia gabonensis seeds and proviron on the biochemical parameters of male guinea pig.

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Asian Pacific Journal of Tropical Medicine 2010年第2期3卷 101-104页

作者： Obianime AW Uche fi Department of Pharmacology University of Port Harcourt Department of Pharmacognosy and Phytotherapy University of Port Harcourt

Objective:To investig.te the phytochemical screening and the effects of the aqueous extracts of the seeds of Irvingia gabonensis on the biochemical parameters of male guinea ***: The biochemical parameters were assayed using Randox Diagnostic kits,Phenolphthalein method and colorimetric *** phytochemical screening was carried out using standard ***:Phytochemical investig.tions revealed the presence of flavonoids,tannins, carbohydrate,alkaloids,terpenoids,steroids,volatile oils,saponins and cardiac *** aqueous extract of Irvingia gabonensis seeds(SO - 400 mg/kg) caused a statistically sig.ificant(Perol,urea,uric acid,total protein,prostatic, alkaline,and acid *** hig.est reduction effect was obtained with uric acid at 400 mg/kg of Irvingia gabonensis extract while the least effect was observed in total cholesterol. These effects were dose- and time- ***:This shows that the seeds of Irvingia gabonensis have hepatoprotective,nephroprotective and cardio protective *** study therefore,supports the claims on the use of the seeds of this plant by traditional medicine practitioners as a hepatoprotective and nephroprotective agent Although further studies need to be done to isolate,identify and characterize the active principles in the seeds of this plant.

关键词： Irvingia gabonensis Phytoconstituents Biochemical parameters Proviron Male guinea pig.

siRNA therapeutics:a clinical reality

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Science China(Life Sciences) 2020年第4期63卷 485-500页

作者： Phei er Saw er-Wei Song Guangdong Provincial Key Laboratory of Malig.ant Tumor Epig.netics and Gene Regulation Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhou 510120China Breast Tumor Center Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhou 510120China Zhongshan School of Medicine Breast SurgeryGuangzhou 510080China

Since the revolutionary discovery of RNA interference(RNAi),a remarkable progress has been achieved in understanding and harnessing gene silencing mechanism;especially in small interfering RNA(siRNA)*** its tremendous potential benefits,major challenges in most siRNA therapeutics remains unchanged-safe,efficient and target oriented delivery of *** years after the discovery of RNAi,siRNA therapeutics finally charts its way into *** we journey through the decades,we reminisce the history of siRNA discovery and its application in a myriad of disease ***,we hig.lig.t the breakthroughs in si RNA therapeutics,with special feature on the first FDA approved RNAi therapeutics Onpattro(Patisiran)and the consideration of effective siRNA delivery system focusing on current siRNA nanocarrier in clinical ***,we present some challenges and multiple barriers that are yet to be fully overcome in siRNA therapeutics.

关键词： siRNA therapeutic disease treatment systemic siRNA delivery clinical application

POSITIVE SOLUTIONS FOR SINGULAR BVPs ON THE POSITIVE HALF-LINE ARISING FROM EPIDEMIOLOGY AND COMBUSTION THEORY

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Acta Mathematica Scientia 2012年第2期32卷 672-694页

作者： Smaïl Djebali Ouiza Saïfi 闫宝强 Department of Mathematics E.N.S.P.O.Box 9216050 Kouba.AlgiersAlgeria Department of Economics Faculty of Economic and Management SciencesAlgiers UniversityAlgeria Department of Mathematics Shandong Normal University

In this work, we are concerned with the existence and multiplicity of positive solutions for singular boundary value problems on the half-line. Two problems from epi- demiology and combustion theory set on the positive half-line are investig.ted upper and lower solution techniques combined with fixed point index on cones in priate Banach spaces. The results complement recent ones in the literature. We use appropriate Banach spaces. The results complement recent ones in the literature.

关键词： fixed points index positive solution singular problem cone lower andupper solution half-line

The effects of aqueous extracts of Tetracarpidium conophorum seeds on the hormonal parameters of male guinea pig.

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Asian Pacific Journal of Tropical Medicine 2010年第1期3卷 21-24页

作者： Obianime AW Uche fi Department of Pharmacology University of Port Harcourt Department of Pharmacognosy and Ethno Therapy University of Port Harcourt

Objective:To investig.te the effects of the aqueous extracts of the seeds of Tetracarpidium conophorum and the effect of Proviron(12.5 mg/kg)(as standard) on the hormonal parameters of male guinea pig.,compare the effects of the seeds of Tetracarpidium conophorum and Proviron,and screen the phytochemical constituents of the seeds of Tetracarpidium ***:The hormonal effects of the Tetracarpidium conophorum and Proviron were tested by hormonal assay,using enzyme immuno assay *** was done by reaction of antibody with serum testosterone and testosterone label,magnetic solid phase separation and colour development *** screening was done using standard procedures. Results:The aqueous extract of the Tetracarpidium conophorum seeds(100-400 mg/kg) caused a statistically sig.ificant increase(Perone of male guinea pig.,from(2.60±0.06) ng/mL to(3.40±0.05) ng/mL,(3.00±0.60) ng/mL and(3.30±0.45) ng/mL on the 7th,14th and 21st day of the administration of the extracts,*** hig.est increase was obtained after the 7th day of treatment[(3.40±0.05) ng/mL].These effects were very comparable to the effects of Proviron on the testosterone of male guinea pig.,which were obtained to be(2.80±0.01) ng/mL,(2.90±0.16) ng/mL and(3.10±0.30) ng/mL on the 7th, 14th and 21st day,*** effects were dose-and *** optimum effect on testosterone level under dose-dependent study f(4.70±0.45) ng/mL]was obtained at 300 mg/kg of Tetracarpidium conophorum after 7 days ***,the phytochemical screening of the seeds of Tetracarpidium conophorum revealed the presence of flavonoids, tannin,alkaloids,carbohydrate,volatile oils,terpenoids,saponins and cardiac glycosides. Conclusion:This study supports the claims on the use of the seeds of this plant by traditional medicine practitioners as a fertility ***,further studies need to be done to isolate and characterize the active pri

关键词： Tetracarpidium conophorum Hormonal parameters Male guinea pig.

Phage display screening of therapeutic peptide for cancer targeting and therapy

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Protein & Cell 2019年第11期10卷 787-807页

作者： Phei er Saw er-Wei Song Guangdong Provincial Key Laboratory of Malig.ant Tumor Epig.netics and Gene Regulation Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Breast Tumor Center Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China

Recently,phage display technology has been announced as the recipient of Nobel Prize in Chemistry *** display technique allows hig. affinity target-binding peptides to be selected from a complex mixture pool of billions of displayed peptides on phage in a combinatorial library and could be further enriched through the biopanning process;proving to be a powerful technique in the screening of peptide with hig. affinity and *** this review,we will first discuss the modifications in phage display techniques used to isolate various cancer-specific lig.nds by in situ,in vitro,in vivo,and ex vivo screening *** will then discuss prominent examples of solid tumor targeting-peptides;namely peptide targeting tumor vasculature,tumor microenvironment(TME)and overexpressed receptors on cancer cells identified through phage display *** will also discuss the current challenges and future outlook for targeting peptidebased therapeutics in the clinics.

关键词： phage display tumor targeting peptide,tumor vasculature tumor microenvironment tumor stromal cells over-expressed receptor

Simple Traits among Diaspore Weig.t/Number,Plant Heig.t and Ability of Vegetative Propagation

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Journal of Integrative Plant Biology 2008年第12期50卷 1563-1569页

作者： Bozena erá Institute of Systems Biology and Ecology Academy of Sciences of the Czech Republiceské Budějovice 37005

Several expected correlations among followed internal plant traits were confirmed using the dataset of 492 herbaceous species from the temporal zone of Central Europe. Average diaspore weig.t （seed mass）, reproductive capacity of population （number of produced diaspores）, species heig.t, and ability of lateral spread were the plant traits considered. The evident correlations were confirmed among all investig.ted traits：（i） The reproductive capacity of population negatively correlated with diaspore weig.t, plant heig.t, and vegetative propagation. The diaspore weig.t and their number are closely correlated and co-adapted. （ii） Big.er plant species produce big.er diaspores. These trends are obvious at the inter- and intra-family levels. （iii） Larger plant species showed hig.er ability to vegetative propagation.

关键词： comparison lateral spread reproduction seed production seed weig.t strategy trade-off.