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Efficacy of He-ne Laser in Combination with Topical Clindamycin in the Treatment of Acne vulgaris (Av)

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Journal of Cosmetics, Dermatological Sciences and Applications 2020年第3期10卷 134-139页

作者： Bui Thi van nguyen ngoc Oanh đặng văn em Huynh Thi Xuan Tam nguyen Lan Anh Pham Thi Minh Phuong Dermatology-venereology and Allergy 108 Central Military Hospital Hanoi Vietnam Dermatology-venereology Department Bach Mai Hospital Hanoi Vietnam Pham ngoc Thach University of Medicine Ho Chi Minh City Vietnam

Objective: To evaluate the efficacy of He-ne laser in combination with topical clindamycin in the treatment of Av at 108 Military Central Hospital from Oct 2015 to Aug 2016. Subjects and Methods: 61 patients with Av w... 详细信息

Objective: To evaluate the efficacy of He-Ne laser in combination with topical clindamycin in the treatment of AV at 108 Military Central Hospital from Oct 2015 to Aug 2016. Subjects and Methods: 61 patients with AV were divided into 2 groups: Group 1: 31 patients were treated with He-Ne laser in combination with topical Clindamycin, Group 2: 30 patients were only treated with topical clindamycin. Laser HE-NE was applied 2 times/week n>for 6 weeks. Result: After 3 months of treatment Group 1: very good—51n>n>.6%, good—48.4%. Group 2: very good—30%, good—50% and moderate—20%. Conclusion: n>The combination of He-Ne laser with topical clindamycin shows more rapid clinical improvement compared to topical clindamycin alone in the treatment of mild and moderate AV.

关键词： Acne vulgaris He-ne Laser Clindamycin

An APPROACH TO AnALYSIS OF SIngLE PIER BASED On THE vARIATIOnAL PRInCIPLE In MULTI-LAYERED SOIL

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Acta Mechanica Solida Sinica 2001年第3期14卷 275-282页

作者： ng Shiu Cho Department of Civil Enginddring The Hong Kong University of Science and TechnologyClearwaler BayHong Kong

In this study, a variational approach to the settlement analysisof an axially loaded pier em- bedded in a multi-layered soil profileis presented. In this method, the soil profile and the embedded pierare divided into a number of sub-layers according to the actualnumber o soil layers observed in the field. The displacement shapefunction of each soil layer is given as a product of an exponentialequation along the pier depth and the Bessel's solution in the radialdirection.

关键词： pier pile settlement

Petrology,geochemistry and source characteristics of the Burpala alkaline massif,north Baikal

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Geoscience Frontiers 2017年第4期8卷 711-719页

作者： n.v.vladykin I.A.Sotnikova vinogradov Institute of Geochemistry Siberian BranchRussian Academy of Sciences

The Burpala alkaline massif contains rocks with more than 50 minerals rich in Zr,nb,Ti,Th,Be and rare earth elements（REE）.The rocks vary in composition from shonkinite,melanocratic syenite,nepheline and alkali syenites to alaskite and alkali granite and contain up to 10%LILE and HSFE,3.6%of REE and varying amounts of other trace elements（4%Zr,0.5%Y,0.5%nb,0.5%Th and 0.1%U）.Geological and geochemical data suggest that all the rocks in the Burpala massif were derived from alkaline magma enriched in rare earth *** extreme products of magma fractionation are REE rich pegmatites,apatite-fiuorite bearing rocks and *** Sr and nd isotope data suggest that the source of primary melt is enriched mantle（em-Ⅱ）.We correlate the massif to mantle plume impact on the active margin of the Siberian continent.

关键词： Syenite Pegmatite Rare metal and rare earths Petrology Geochemistry

Extrapolation-Based Acceleration of Iterative Solvers:Application to Simulation of 3D Flows

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Communications in Computational Physics 2011年第3期9卷 607-626页

作者： Leopold Grinberg George em Karniadakis Division of Applied Mathematics Brown UniversityProvidence 02912USA

We investigate the effectiveness of two extrapolation-based methods aiming to approximate the initial state required by an iterative solver in simulations of unsteady flow *** methods lead to about a ten-fold reduction in the iteration count while requiring only negligible computational *** are particularly suitable for parallel computing since they are based almost exclusively on data stored locally on each *** has been evaluated in simulations of turbulent flow in a stenosed carotid artery and also in laminar flow in a very large domain containing the human intracranial arterial tree.

关键词： High-order methods POD CFD low-energy preconditioner

A Scalable Domain Decomposition Method for Ultra-Parallel Arterial Flow Simulations

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Communications in Computational Physics 2008年第10期4卷 1151-1169页

作者： Leopold Grinberg George em Karniadakis Division of Applied Mathematics Brown UniversityProvidence 02912USA

Ultra-parallel flow simulations on hundreds of thousands of processors require new multi-level domain decomposition *** we present such a new two-level method that has features both of discontinuous and continuous Galerkin ***,at the coarse level the domain is subdivided into several big patches and within each patch a spectral element discretization(fine level)is *** interface conditions for the navier-Stokes equations are developed to connect the patches,relaxing the C0 continuity and minimizing data transfer at the patch *** perform several 3D flow simulations of a benchmark problem and of arterial flows to evaluate the performance of the new method and investigate its accuracy.

关键词： Bioflows spectral elements discontinuous Galerkin parallel computing

Efficient and Accurate numerical Methods Using the Accelerated Spectral Deferred Correction for Solving Fractional Differential Equations

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numerical Mathematics(Theory,Methods and Applications) 2022年第4期15卷 876-902页

作者： Xuejuan Chen Zhiping Mao George em Karniadakis School of Science Jimei UniversityXiamen 361021China School of Mathematical Sciences Fujian Provincial Key Laboratory of Mathematical Modeling and High-Performance Scientific ComputingXiamen UniversityXiamenChina Division of Applied Mathematics Brown UniversityProvidenceRI 02912USA

We develop an efficient and accurate spectral deferred correction(SDC)method for fractional differential equations(FDEs)by extending the algorithm in[14]for classical ordinary differential equations(ODEs).Specifically,we discretize the resulted Picard integral equation by the SDC method and accelerate the convergence of the SDC iteration by using the generalized minimal residual algorithm(GMRES).We first derive the correction matrix of the SDC method for FDEs and analyze the convergence region of the SDC *** then present several numerical examples for stiff and non-stiff FDEs including fractional linear and nonlinear ODEs as well as fractional phase field models,demonstrating that the accelerated SDC method is much more efficient than the original SDC method,especially for stiff ***,we resolve the issue of low accuracy arising from the singularity of the solutions by using a geometric mesh,leading to highly accurate solutions compared to uniform mesh solutions at almost the same computational ***,for long-time integration of FDEs,using the geometric mesh leads to great computational savings as the total number of degrees of freedom required is relatively small.

关键词： Stiff problem generalized minimal residual geometric mesh refinement long time evolution fractional phase field models

Predicting the aquatic risk of realistic pesticide mixtures to species assemblages in Portuguese river basins

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Journal of Environmental Sciences 2015年第5期27卷 12-20页

作者： emília Silva Michiel A.Daam Maria José Cerejeira Centro de Engenharia dos Biossistemas (CEER) Instituto Superior de Agronomia (ISA) University of Lisbon (UL) Tapada da Ajuda1349-017 Lisbon Portugal

Although pesticide regulatory tools are mainly based on individual substances, aquatic ecosystems are usually exposed to multiple pesticides from their use on the variety of crops within the catchment of a river. This study estimated the impact of measured pesticide mixtures in surface waters from 2002 and 2008 within three important Portuguese river basins（＇Mondego＇, ＇Sado＇ and ＇Tejo＇） on primary producers, arthropods and fish by toxic pressure calculation. Species sensitivity distributions（SSDs）, in combination with mixture toxicity models, were applied. Considering the differences in the responses of the taxonomic groups as well as in the pesticide exposures that these organisms experience, variable acute multi-substance potentially affected fractions（ms PAFs） were obtained. The median msP AF for primary producers and arthropods in surface waters of all river basins exceeded 5%, the cut-off value used in the prospective SSD approach for deriving individual environmental quality standards. A ranking procedure identified various photosystem II inhibiting herbicides, with oxadiazon having the relatively largest toxic effects on primary producers, while the organophosphorus insecticides, chlorfenvinphos and chlorpyrifos, and the organochloride endosulfan had the largest effects on arthropods and fish, respectively. These results ensure compliance with European legislation with regard to ecological risk assessment and management of pesticides in surface waters.

关键词： Pesticides Mixtures Risk assessment Multi-substance potentially affected fraction Surface waters

When to pull the trigger in nonazoospermic infertile men undergoing intracytoplasmic sperm injection?

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Asian Journal of Andrology 2020年第4期22卷 439-440页

作者： Sandro C Esteves Sheena em Lewis AnDROFERT Andrology and Human Reproduction ClinicReferral Center for Male Reproduction13075-460 CampinasSPBrazil Department of Surgery(Division of Urology) University of Campinas(UNICAMP)13083-887 CampinasSPBrazil Faculty of Health Aarhus University8000 AarhusDenmark Queens University Belfast Northern Ireland BT71NNUK Examenlab Ltd. Weavers Court Business ParkLinfield RoadBelfastNorthern Ireland BT125GHUK

Before the era of intracytoplasmic sperm injection(ICSI),few options were available for men with severe infertility to father a biological *** in 1992 as a modification of conventional in vitro fertilization,ICSI has enabled men with low sperm quantity and quality to have their own biological offspring.[1]Among nonazoospermic infertile men,ICSI has been traditionally carried out with ejaculated *** contrast,methods to harvest sperm from the epididymides and testes are used for ICSI in men with azoospermia-related infertility.

关键词： injection infertility traditionally

Error Control in Multi-Element Generalized Polynomial Chaos Method for Elliptic Problems with Random Coefficients

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Communications in Computational Physics 2009年第2期5卷 793-820页

作者： Xiaoliang Wan George em Karniadakis Division of Applied Mathematics Brown UniversityProvidenceRI 02912USA

We develop the theory for a robust and efficient adaptive multi-element generalized polynomial chaos(ME-gPC)method for elliptic equations with random coefficients for a moderate number(O(10))of random *** employ loworder(p≤3)polynomial chaos and refine the solution using adaptivity in the parametric *** first study the approximation error of ME-gPC and prove its *** subsequently generate local and global a posteriori error *** order to resolve the error equations efficiently,we construct a reduced space using much smaller number of terms in the enhanced polynomial chaos space to capture the errors of ME-gPC *** on the a posteriori estimators,we propose and implement an adaptive ME-gPC algorithm for elliptic problems with random *** results for convergence and efficiency are also presented.

关键词： Stochastic PDE a posteriori error estimate elliptic problems adaptive numerical methods uncertainty quantification