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Chinese Journal of Polymer Science 2012年第6期30卷 796-807页

作者： Ismet Kaya Ali Avci özlem gültekin Canakkale Onsekiz Mart University Faculty of Sciences and ArtsDepartment of Chemistry17020CanakkaleTurkey Celal Bayar University Faculty of Sciences and ArtsDepartment of Chemistry45040ManisaTurkey

Schiff base monomers [2-（4-bromobenzylideneamino）phenol and 2-（4-bromobenzylideneamino）-5-methylphenol] were synthesized by the condensation reaction of 4-bromobenzaldehyde with aromatic aminophenols. Then, the monomers were converted to their polyphenol derivatives by oxidative polycondensation reactions （OP） in an aqueous alkaline medium. The structures of the synthesized compounds were characterized by solubility tests, FT-IR, NMR, Tg-DTA, DSC and SEC techniques. The HOMO-LUMO energy levels and electrochemical （E＇g） and optical （Eg） band gaps were calculated from cyclic voltammetry （CV） and UV-Vis measurements, respectively. Cyclic voltammetry （CV） was used to determine the electrochemical oxidation-reduction characteristics. Optical properties were investigated by UV-Vis and fluorescence analyses. Solid state electrical conductivities were measured on polymer films by four point probe technique using a Keithley 2400 electrometer. The effects of electron-donating （--CH3） group at p-position of --NH2 group in aminophenol on electrochemical and thermal properties were also discussed. Photoluminescence （PL） properties of the synthesized materials were determined in solution forms using different solvents. Fluorescence measurements were carried out in various concentrated solutions to determine the optimum concentrations to obtain the maximal PL intensities.

关键词： Schiff base polymers Thermal analysis Fluorescence Cyclic voltammetry Conductivity.

Advances in the treatment of autism spectrum disorder:Wharton jelly mesenchymal stem cell transplantation

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World Journal of Methodology 2025年第1期15卷 72-79页

作者： Serdar Kabatas ErdinçCivelek Eyüp Can Savrunlu Umut Karaaslan Özlem Yıldız Erdal Karaöz Department of Neurosurgery University of Health Sciences TurkeyGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Pediatric Allergy-Immunology Institute of Health Sciences Marmara UniversityIstanbul 34865Türkiye Center for Stem Cell&gene Therapy Research and Practice University of Health Sciences TurkeyIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry University of Health SciencesGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry Kocaeli University Faculty of MedicineKocaeli 41001Türkiye Center for Regenerative Medicine and Stem Cell Research&Manufacturing Liv HospitalIstanbul 34340Türkiye Department of Histology and Embryology Istinye UniversityFaculty of MedicineIstanbul 34010Türkiye Center for Stem Cell and Tissue Engineering Research and Practice Istinye UniversityIstanbul 34340Türkiye

BACKgROUND Autism spectrum disorder(ASD)is a complex neurodevelopmental disorder with multifaceted *** recent studies,neuroinflammation and immune dysregulation have come to the forefront in its *** are studies suggesting that stem cell therapy may be effective in the treatment of *** To evolve the landscape of ASD treatment,focusing on the potential benefits and safety of stem cell *** A detailed case report is presented,displaying the positive outcomes observed in a child who underwent intrathecal and intravenous Wharton’s jelly-derived mesenchymal stem cells(WJ-MSCs)transplantation combined with *** The study demonstrates a significant improvement in the child’s functional outcomes(Childhood Autism Rating Scale,Denver 2 Developmental Screening Test),especially in language and gross motor *** serious side effects were encountered during the 2-year *** The findings support the safety and effectiveness of WJ-MSC transplantation in managing ASD.

关键词： Autism spectrum disorder Neurorehabilitation Stem cell transplantation Wharton jelly mesenchymal stem cells Inflammation

Cellular and molecular mechanisms in the pathogenesis of liver fibrosis:An update

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World Journal of gastroenterology 2014年第23期20卷 7260-7276页

作者： gülsüm ?zlem Elpek Department of Pathology Akdeniz University Medical School07070 AntalyaTurkey

There have been considerable recent advances towards a better understanding of the complex cellular and molecular network underlying liver *** data indicate that the termination of fibrogenic processes and the restoration of deficient fibrolytic pathways may allow the reversal of advanced fibrosis and even ***,efforts have been made to better clarify the cellular and molecular mechanisms that are involved in liver *** of hepatic stellate cells(HSCs)remains a central event in fibrosis,complemented by other sources of matrix-producing cells,including portal fibroblasts,fibrocytes and bone marrow-derived *** cells converge in a complex interaction with neighboring cells to provoke scarring in response to persistent *** the interaction of different cell types,revealing the effects of cytokines on these cells and characterizing the regulatory mechanisms that control gene expression in activated HSCs will enable the discovery of new therapeutic ***,the characterization of different pathways associated with different etiologies aid in the development of disease-specific *** article outlines recent advances regarding the cellular and molecular mechanisms involved in liver fibrosis that may be translated into future *** pathogenesis of liver fibrosis associated with alcoholic liver disease,non-alcoholic fatty liver disease and viral hepatitis are also discussed to emphasize the various mechanisms involved in liver fibrosis.

关键词： Liver Liver fibrosis Cirrhosis Fibrogenesis Hepatic stellate cells Myofibroblast Extracellular matrix

Cylinder Pressure Prediction of An HCCI Engine Using Deep Learning

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Chinese Journal of Mechanical Engineering 2021年第2期34卷 160-167页

作者： Halit Yaşar gültekinÇağıl Orhan Torkul MerveŞişci Department of Mechanical Engineering Engineering FacultySakarya UniversityEsentepe Campus54187 SerdivanSakaryaTurkey Department of Industrial Engineering Engineering FacultySakarya UniversityEsentepe Campus54187 SerdivanSakaryaTurkey

Engine tests are both costly and time consuming in developing a new internal combustion ***,it is of great importance to predict engine characteristics with high accuracy using artificial ***,it is possible to reduce engine testing costs and speed up the engine development *** Learning is an effective artificial intelligence method that shows high performance in many research areas through its ability to learn high-level hidden features in data *** present paper describes a method to predict the cylinder pressure of a Homogeneous Charge Compression Ignition(HCCI)engine for various excess air coefficients by using Deep Neural Network,which is one of the Deep Learning methods and is based on the Artificial Neural Network(ANN).The Deep Learning results were compared with the ANN and experimental *** results show that the difference between experimental and the Deep Neural Network(DNN)results were less than 1%.The best results were obtained by Deep Learning *** cylinder pressure was predicted with a maximum accuracy of 97.83%of the experimental value by using *** the other hand,the accuracy value was increased up to 99.84%using *** results show that the DNN method can be used effectively to predict cylinder pressures of internal combustion engines.

关键词： Artificial neural network Deep neural network HCCI engine Cylinder pressure Excess air coefficient

Bell Polynomial Approach for the Solutions of Fredholm Integro- Differential Equations with Variable Coefficients

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Computer Modeling in Engineering & Sciences 2020年第6期123卷 973-993页

作者： gökçe Yıldız gültekin Tınaztepe Mehmet Sezer Department of Mathematics Faculty of ScienceManisa Celal Bayar UniversityManisaTurkey Vocational School of Technical Sciences Akdeniz UniversityAntalyaTurkey

In this article,we approximate the solution of high order linear Fredholm integro-differential equations with a variable coefficient under the initial-boundary conditions by Bell *** collocation points and treating the solution as a linear combination of Bell polynomials,the problem is reduced to linear system of equations whose unknown variables are Bell *** solution to this algebraic system determines the approximate *** estimation of approximate solution is *** examples are provided to illustrate the performance of the *** numerical results are compared with the collocation method based on Legendre polynomials and the other two methods based on Taylor *** is observed that the method is better than Legendre collocation method and as accurate as the methods involving Taylor polynomials.

关键词： Bell polynomials collocation points matrix method Fredholm integrodifferential equations.

Stepping up after spinal cord injury:negotiating an obstacle during walking

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Neural Regeneration Research 2025年第7期20卷 1919-1929页

作者： Alain Frigon Charly g.Lecomte Department of Pharmacology-Physiology Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate *** spinal cord injury,stepping over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including the parietal cortex,premotor cortex,and motor *** information and planning are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiology obstacle negotiation spinal cord injury

Fixing an illusion–an empirical assessment of correction methods for the terrain reversal effect in satellite images

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International Journal of Digital Earth 2020年第10期13卷 1135-1150页

作者： gianna Hartung Arzu Çöltekin Department of geography University of ZurichZurichSwitzerland FHNW University of Applied Sciences and Arts Northwestern ZurichSwitzerland

Identifying land forms and land cover classes are important tasks in image ***,a phenomenon called terrain reversal effect(TRE)causes an inverted perception of 3D *** this inversion occurs,valleys appear as ridges and vice *** the TRE can severely impair the ability to identify 3D land forms,‘correcting’for the TRE in imagery can introduce new ***,one of most commonly-proposed methods–shaded relief map(SRM)overlay–appears to impair the ability to identify land cover *** this paper,we report a comparative empirical evaluation of an SRM overlay solution,and its‘enhanced’versions supported by various other cues(stereopsis,motion,labels).In response to the different solutions,we measure the effectiveness,efficiency,confidence and preferences of our participants in land form and land cover identification *** examined methods significantly improve the ability to detect land forms accurately,but they also impair the ability to identify the land cover classes to different ***,participants’visualization preferences contradict their performance with them,calling for reflection on the visual effects of the applied correction *** on the study,recommendations concerning the correction of the TRE are drawn,and gaps are identified.

关键词： Terrain reversal effect satellite images correction methods shaded relief map stereoscopy motion

Spatial and seasonal distribution of macroinvertebrates in high altitude reservoir (Beyler Reservoir, Turkey)

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Chinese Journal of Oceanology and Limnology 2013年第5期31卷 994-1001页

作者： zlem FINDIK Arts and Sciences Faculty Molecular Biology and Genetic DepartmentNevehir University

A highland reservoir in the West Black Sea region of Turkey which belongs to the Mediterranean climatic zone was *** littoral and profundal zones were sampled from October 2009 to September 2010,to determine taxonomic composition,biodiversity and abundance of benthic invertebrates as well as the seasonal variation of these measures.A total of 35 taxa were identified,of which 12 belong to Chironomidae and 10 to Oligochaeta *** highest diversity and abundance of benthic macroinvertebrates were found at the littoral *** showed significant positive correlations with water temperature and NO_2 and NO_3 concentrations,and negative correlation with dissolved oxygen.

关键词： macrofauna zoobenthos community structure littoral West Black Sea

Comparing the terrain reversal effect in satellite images and in shaded relief maps:an examination of the effects of color and texture on 3D shape perception from shading

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International Journal of Digital Earth 2019年第4期12卷 442-459页

作者： Arzu Çöltekin Julien Biland Department of geography University of ZurichZurichSwitzerland Department of geography University of BernBernSwitzerland

Terrain reversal effect(TRE)causes reversed 3D shape perception in satellite images and shaded relief maps(SRMs),and introduces difficulties in identifying landforms such as valleys and *** this paper,in a controlled laboratory experiment,we compare how well 27 participants could identify valleys and ridges over 33 locations using SRMs,color satellite images and grayscale satellite *** main depth cue is shadow both in vertical-view images and ***,the presence of texture and color in images also affect 3D shape *** our participants experience the illusion strongly:with the SRMs,it is very severe(2%accuracy),with grayscale images low but considerably better than SRMs(17.6%accuracy),and slightly worse with color imagery(15.3%accuracy).These differences between SRMs and imagery suggest that the participants who are able to bypass the illusion consciously or subconsciously interpret the photographic *** support this observation further with a cue-strength ***,we provide exploratory analyses of the effects of expertise,global convexity bias,and bistable *** original empirical observations serve towards a better understanding of this visual illusion,and contribute towards nuanced and appropriate solutions to correcting for TRE differently for satellite images and SRMs.

关键词： Terrain reversal relief inversion false topographic perception phenomenon photo interpretation visual illusion user study bistable perception global convexity bias

An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of geotechnical Structures

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski g.V.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)