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World Journal of Gastroenterology 2024年第12期30卷 1727-1738页

作者： Hong Peng Si-Yi Lei Wei Fan Yu Dai Yi zhang Gen Chen Ting-Ting Xiong Tian-Zhao Liu Yue Huang Xiao-Feng Wang Jin-Hui Xu Xin-Hua Luo Department of Infectious Diseases Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina Department of Hepatobiliary Surgery Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina

BACKGROUND Sarcopenia may be associated with hepatocellular carcinoma(HCC)following *** traditional single clinical variables are still insufficient to predict *** still lack effective prediction models for recent recurrence(time to recurrence3 hepatitis B-related HCC patients who underwent curative hepatectomy for the first time,and the skeletal muscle index at the third lumbar spine was measured by preoperative computed tomography.94 of these patients were enrolled for external *** multivariate analysis was per-formed to identify the risk factors of postoperative recurrence in training cohort.A nomogram model was developed to predict the RFS of HCC patients,and its predictive performance was *** predictive efficacy of this model was evaluated using the receiver operating characteristic *** Multivariate analysis showed that sarcopenia[Hazard ratio(HR)=1.767,95%CI:1.166-2.678,Png/mL(HR=1.984,95%CI:1.307-3.011,P5 cm(HR=2.222,95%CI:1.285-3.842,P3.135,Png cohort(sensitivity 81%,specificity 63%)and 0.773(95%CI:0.707-0.838)in the validation ***,a SAMD score≥110 was better to distinguish the high-risk group of postoperative recurrence of *** Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-rel

关键词： Alpha-fetoprotein Hepatitis B virus Hepatectomy Hepatocellular carcinoma Nomogram Predictive models Recurrence Recurrence-free survival Risk factors Sarcopenia

Development of an industrial Internet of things suite for smart factory towards re-industrialization

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Advances in Manufacturing 2017年第4期5卷 335-343页

作者： C. K. M. Lee S. Z. zhang K. K. H. ng Department of Industrial and Systems Engineering The Hong Kong Polytechnic University Hong Kong People's Republic of China Department of Information Management Zhejiang University of Finance and Economics Hangzhou 310018Zhejiang People's Republic of China

Re-industrialization, which supports industrial upgrading and transformation, promotes smart production and high value-added manufacturing processes, and helps to create new momentum for the economic. Under the current situation, industrialists encounter several chal- lenges to achieve re-industrialization. Firstly, the cost and technical thresholds for industrialists to leverage emerging technologies are high. Secondly, there are huge quantities and numerous types of Internet of things （IoT） devices in smart factories, warehouses and offices. The enormous extents of data exchange and communication, manage- ment, monitoring and control of IoT devices as well as the establishment and maintenance of a reliable cloud platform hinder industrialists to implement an integrated smart production management. Therefore, to achieve re-indus- trialization, an industrial Internet of things （IIoT） suite consisting of a micro-services-based IIoT cloud platform and IIoT-based smart hub is proposed, which helps to materialize re-industrialization and to conduct industrial upgrading and transformation to achieve smart production and high value-added manufacturing processes.

关键词： Industrial Intemet of things (IIoTs) Cloudplatform Micro-services-based Industry 4.0 Reindustrialization

A guide to use fluorinated aromatic bulky cations for stable and high-performance 2D/3D perovskite solar cells:The more fluorination the better?

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Journal of Energy Chemistry 2022年第1期31卷 179-189,I0006页

作者： Lei Wang Qin Zhou Zilong zhang Wenbo Li Xiaobing Wang Qi ng Tian Xiaoyan Yu Ting Sun Jihuai Wu Bao zhang Peng Gao School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China CAS Key Laboratory of Design and Assembly of Functional Nanostructures and Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002FujianChina Laboratory for Advanced Functional Materials.Xiamen Institute of Rare Earth Materials Haixi InstituteChinese Academy of SciencesXiamen 361021FujianChina College of Materials Science and Engineering Huaqiao University361021 XiamenFujianChina

While serious stability issues impede the commercialization of perovskite solar cells(PSCs),two-dime nsional(2D)perovskites based on fluorinated bulky cations have emerged as more intrinsically stable ***,the influence of fluorination degree of the bulky aromatic cation on the per-formance of resulting PSCs has not been ***,2D perovskites(FxPEA)_(2)PbI_(4)(x=1,2,3,5)are grown in situ on the surface of the three-dime nsion al(3D)perovskite and dem on strate effective passivation of the surface defects of 3D *** power conversion efficiency(PCE)of the optimized devices were boosted from 20.75%for the control device to 21.09%,22.06%,22.74%and 21.86%for 2D/3D devices treated with 4-fluorophenethylamine iodide,3,5-difluorophenylethylamine iodide,2,4,5-trifluoroethylphenylethylamine iodide,and 1,2,3,4,5-pentafluorophenylethylamine iodide,*** firstly reported two unexplored RP-type layered perovskites with F_(2)PEAI and F_(3)PEAI as bulky *** combined experimental and theoretical analysis revealed the reasons behind the various morphology,device performances,dynamic behavior,and humidity *** best performing F_(5)PEAI-treated device retaining 95.0%of its initial PCE under ambient atmosphere(with RH of 60%±5%)without encapsulation for 300 h *** work provides useful guidance for selecting fluorinated bulky cations with different molecular electronic properties,which will play an essential role in further improving the performance/stability of PSCs for the sake of further commercialization.

关键词： 2D perovskite Fluorinated spacer cation Perovskite solar cells Passivation Stability

滁河南京段环境介质中环状挥发性甲基硅氧烷的污染水平与生态风险评价

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生态与农村环境学报 2024年第2期40卷 213-221页

作者：张伟古文范德玲张冰王蕾石利利南京信息工程大学环境科学与工程学院江苏南京210044 生态环境部南京环境科学研究所江苏南京210042

环状挥发性甲基硅氧烷(cVMSs)因进入环境后存在潜在生态风险而受到广泛关注。研究采样测定滁河南京段地表水、沉积物及周边土壤中八甲基环四硅氧烷(D4)、十甲基环五硅氧烷(D5)和十二甲基环六硅氧烷(D6)3种cVMSs的浓度水平,并对其生态风... 详细信息

环状挥发性甲基硅氧烷(cVMSs)因进入环境后存在潜在生态风险而受到广泛关注。研究采样测定滁河南京段地表水、沉积物及周边土壤中八甲基环四硅氧烷(D4)、十甲基环五硅氧烷(D5)和十二甲基环六硅氧烷(D6)3种cVMSs的浓度水平,并对其生态风险进行了评价。结果表明:地表水中D4、D5、D6的检出率分别为38.1%、95.2%、100%,总含量范围为13.66~77.90 ng·L^(-1),平均值为47.82 ng·L^(-1);沉积物中D4、D5、D6的检出率分别为66.7%、86.7%、100%,总含量范围为0.56~49.74μg·kg^(-1),平均值为13.95μg·kg^(-1);土壤中D4、D5、D6的检出率分别为66.7%、20%、100%,总含量范围为1.90~7.05μg·kg^(-1),平均值为3.57μg·kg^(-1)。地表水和土壤中D6的检出浓度最高,沉积物中则为D5,对比国内外其他地区的相关结果,cVMSs处于中低水平。生态风险评价结果显示,滁河南京段水体中cVMSs存在中高风险。

关键词：甲基硅氧烷生态风险浓度水平滁河南京段

Peritoneal macrophages attenuate retinal ganglion cell survival and neurite outgrowth

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Neural Regeneration Research 2021年第6期16卷 1121-1126页

作者： Jia-Jian Liang Yu-Fen Liu Tsz Kin ng Ci-Yan Xu Mingzhi zhang Chi Pui Pang Ling-Ping Cen Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong ShantouGuangdong ProvinceChina Shantou University Medical College ShantouGuangdong ProvinceChina Department of Ophthalmology and Visual Sciences the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Inflammation is a critical pathophysiological process that modulates neuronal survival in the central nervous system after disease or ***,the effects and mechanisms of macrophage activation on neuronal survival remain *** the present study,we co-cultured adult Fischer rat retinas with primary peritoneal macrophages or zymosan-treated peritoneal macrophages for 7 *** analysis revealed that peritoneal macrophages reduced retinal ganglion cell survival and neurite outgrowth in the retinal explant compared with the control *** addition of zymosan to peritoneal macrophages attenuated the survival and neurite outgrowth of retinal ganglion *** media from peritoneal macrophages also reduced retinal ganglion cell survival and neurite *** result suggests that secretions from peritoneal macrophages mediate the inhibitory effects of these *** addition,increased inflammationand oxidation-related gene expression may be related to the enhanced retinal ganglion cell degeneration caused by zymosan *** summary,this study revealed that primary rat peritoneal macrophages attenuated retinal ganglion cell survival and neurite outgrowth,and that macrophage activation further aggravated retinal ganglion cell *** study was approved by the Animal Ethics Committee of the Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong,Shantou,Guangdong Province,China,on March 11,2014(approval ***20140311(2)-P01).

关键词： in vitro inflammation macrophages model neurite outgrowth optic nerve retinal ganglion cells survival

Epidemiological Characteristics of Influenza A and B in Macau,2010–2018

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Virologica Sinica 2021年第5期36卷 1144-1153页

作者： Hoi Man ng Teng zhang Guoliang Wang Si Meng Kan Guoyi Ma Zhe Li Chang Chen Dandan Wang Meng In Wong Chio Hang Wong Jinliang Ni Xiaohua Douglas zhang Clinical Laboratory Kiang Wu Hospital Faculty of Health Sciences University of Macau

Influenza is one of the major respiratory diseases in humans. Macau is a tourist city with high density of population and special population mobility. The study on the epidemiological characteristics of influenza in Macau should bring great value for preventing influenza in tourist cities like Macau in the world. In this study, we collected a total of 104,874 samples with influenza-like illness(ILI) in Macau from 2010 to 2018. Chi-square test and binary multivariable logistic regression were used to investigate the epidemiological characteristics of influenza A and B in Macau. Among these ILI samples, the overall positive rate is 17.17% for influenza A and 6.97% for influenza B. The epidemics of influenza in three years(i.e., 2012, 2017 and 2018) differ from the remaining years(i.e., normal years). In a normal year, influenza A occurs year-round whereas influenza B is seasonal. Our research shows significant differences in influenza infections between different age groups in normal years. Interestingly, our analysis shows no significant difference between locals and tourists in influenza A and B infection in a normal year, whereas the odds of influenza A in tourists were significantly higher than those in locals in July 2017 and the odds of influenza B in tourists were significantly higher than those in locals in January–February 2012 and January–February 2018. This is possibly attributed by the policy of free vaccination to everyone in Macau. These findings should be valuable for preventing influenza in not only Macau but also the world.

关键词： Influenza Epidemiology Chi-square test Logistic regression Macau

Impact of the biological definition of Alzheimer’s disease using amyloid, tau and neurodegeneration (ATN):what about the role of vascular changes,inflammation,Lewy body pathology?

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Translational Neurodegeneration 2018年第1期7卷 111-117页

作者： S.Gauthier H.zhang K.P.ng T.A.Pascoal P.Rosa-Neto McGill Center for Studies in Aging Douglas Mental Health Research InstituteMontrealCanada Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Neurology National Neuroscience InstituteSingaporeSingapore

Background:The NIA-AA research framework proposes a biological definition of Alzheimer’s disease,where asymptomatic persons with amyloid deposition would be considered as having this disease prior to ***:Notwithstanding the fact that amyloid deposition in isolation is not associated with dementia,even the combined association of amyloid and tau pathology does not inevitably need to dementia over age *** pathological factors may play a leading or an accelerating role in age-associated cognitive decline,including vascular small vessel disease,neuroinflammation and Lewy Body ***:Research should aim at understanding the interaction between all these factors,rather than focusing on them *** this will lead to a personalized approach to the prevention of brain aging,based on individual biological,genetic and cognitive profiles.

关键词： Alzheimer’s disease Diagnosis Treatment Biomarkers Precision medicine Translational research Brain imaging Database analysis Human volunteer cohorts

Solution-processed n-type Bi_2Te_(3-x)Se_x nanocomposites with enhanced thermoelectric performance via liquid-phase sintering

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Science China Materials 2019年第3期62卷 389-398页

作者： Chaohua zhang Chunxiao zhang Hongkuan ng Qihua Xiong College of Materials Science and Engineering Shenzhen Key Laboratory of Special Functional MaterialsShenzhen UniversityShenzhen 518060China Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingapore 637371Singapore

The much slower progress in enhancing the thermoelectric performance of n-type Bi2Te3 than that of p-type Bi2Te3 based materials in the past decade hinders the widespread use in power generation and refrigeration. Here, a facile bottom-up solution-synthesis with spark plasma sintering(SPS) process has been developed to build n-type Bi2Te3-xSex bulk nanocomposites, which substantially improves the power factor and decreases the lattice thermal conductivity by tuning the interface scattering of phonons and electrons. The stoichiometric composition in ternary Bi2Te3-xSex nanocomposites is also tuned to optimize the carrier concentration and lattice thermal conductivity. The optimized bulk nanocomposite Bi2Te2.7Se0.3 exhibits a ZT of 1.1 at^371 K, which is comparable to the corresponding commercially available ingots. Our results demonstrate the great potential of the solution-processed n-type Bi2Te3-xSex nanocomposites for cost-effective thermoelectric applications.

关键词： thermoelectric liquid-phase sintering nanocomposites solution-processed bismuth telluride

Differential Occupational Health Risks between Methylated PAHs and PAHs:Monitoring 126 PAHs and 6 Oxidative Stress Markers in Paired Serum−Urine Samples

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Environment & Health 2024年第3期2卷 150-160页

作者： Ke-Xin Zhao Chao Jiang Yue Han Wen-Long Li Yu-Wei Li Li-Yan Liu Wan-Li Ma Ying-Hua Hu Zi-Feng zhang International Joint Research Center for Persistent Toxic Substances(IJRC-PTS) State Key Laboratory of Urban Water Resource and Environment/School of EnvironmentHarbin Institute of Technology(HIT)Harbin 150090China Wadsworth Center New York State Department of Healthand Department of Environmental Health SciencesSchool of Public HealthState University of New York at AlbanyAlbanyNew York 12237United States

The hazards of polycyclic aromatic hydrocarbons(PAHs)on occupationally exposed population have been widely ***,the occupational exposure risks associated their derivatives,methylated PAHs,remain poorly *** study conducted a screen of 126 PAHs and 6 oxidative stress biomarkers(OSBs)in paired serum−urine samples from 110 petrochemical workers to assess the risk associated with different PAHs *** results showed that the median concentrations of unmetabolized 16 priority PAHs(p-PAHs),16 regular PAHs(R-PAHs),50 methyl-PAHs(Me-PAHs),and 30 nitro-PAHs(N-PAHs)in serum(urine)were 97.98(66.46),11.02(0.00),77.76(31.77),and 1.93(0.10)ng/mL,*** median concentration of metabolized hydroxy PAHs(OH-PAHs)in urine was 12.00 ng/mL(9.49 ng/mg creatinine).OSBs indicate that the hazards of Me-PAHs on exposed populations manifest as protein damage,while the hazards of p-PAHs mainly result in lipid and DNA *** from common diseases and PAH exposure demonstrate a correlation between liver damage and PAH exposure,and Me-PAHs are more difficult to metabolize through urine due to their stronger *** study suggests that traditional health screenings targeting p-PAHs may be insufficient and likely underestimate the exposure risks for occupational populations.

关键词： Petrochemical workers Methyl-PAHs Nitro-PAHs Oxidative stress biomarkers Health risk

Learning Written English: The Perspective of Chinese ESL Students

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外国语言文学 2007年第4期24卷 247-253页

作者： Wailan ng Grace zhang Department of Languages and Intercultural Education Curtin University of Technology Australia

This study intends to identify the perceived difficulties of Chinese ESL students writing in English and their possible *** particular,it aims to study the similarities and differences between the perceptions of Chinese ESL students and their ESL teachers.A total of 20 informants,consisting of ten Chinese ESL students and ten ESL teachers,evaluated three compositions written by Chinese ESL *** Student Evaluators and Teacher Evaluators were interviewed in order to have an in-depth understanding of their perceptions.

关键词：英语教学高校第二语言习得写作教学应用语言学