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Study on the optimal incident proton energy of ^(7)Li(p,n)^(7)Be neutron source for boron neutron capture therapy

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Nuclear Science and Techniques 2024年第3期35卷 170-180页

作者： Yi-Nan Zhu Zuo-Kang Lin Hai-Yan Yu Ye dai Zhi-Min dai Xiao-{2. Yu Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Science Beijing 100049China

Boron neutron capture therapy(BNCT)is recognized as a precise binary targeted radiotherapy technique that effectively eliminates tumors through the^(10)B(n,α)^(7)Li nuclear *** various neutron sources,accelerator-based sources have emerged as particularly promising for BNCT ***^(7)Li(p,n)^(7)Be reaction is highly regarded as a potential neutron source for BNCT,owing to its low threshold energy for the reaction,significant neutron yield,appropriate average neutron energy,and additional *** study utilized Monte Carlo simulations to model the physical interactions within a lithium target subjected to proton bombardment,including neutron moderation by an MgF_(2.moderator and subsequent BNCT dose analysis using a Snyder head *** study focused on calculating the yields of epithermal neutrons for various incident proton energies,finding an optimal energy at 2.7 ***,the Snyder head phantom was employed in dose simulations to validate the effectiveness of this specific incident energy when utilizing a^(7)Li(p,n)^(7)Be neutron source for BNCT purposes.

关键词： Boron neutron capture therapy ^(7)Li(p,n)7Be neutron source Incident proton energy Monte Carlo simulation

Unraveling the mysteries of volatile cycling and habitability on Earth and beyond

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National Science Review 2024年第06期11卷 8-9页

作者： Yi-Gang Xu Ri-Xiang Zhu Min-han dai State Key Laboratory of Isotope Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences State Key Laboratory of Lithosphere Evolution Institute of Geology and Geophysics Chinese Academy of Sciences State Key Laboratory of Marine Environmental Science Xiamen University

The origin and cycling of volatiles, including water, carbon dioxide, and nitrogen, are fundamental to the very existence of habitable planets. These volatile compounds, often taken for granted,are the lifeblood of planetary systems, influencing almost everything from atmospheric composition and climate regulation to deep Earth processes and the emergence of life.

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Emerging clinical relevance of microbiome in cancer:promising biomarkers and therapeutic targets

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Protein & Cell 2024年第4期15卷 239-260页

作者： Jia-Hao dai Xi-Rong Tan han Qiao Na Liu State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510050China

The profound influence of microbiota in cancer initiation and progression has been under the spotlight for years,leading to numerous researches on cancer microbiome entering clinical *** promising biomarkers and therapeutic targets,the critical involvement of microbiota in cancer clinical practice has been increasingly ***,recent progress in this field is *** describe the potential of tumor-associated microbiota as effective diagnostic and prognostic biomarkers,*** addition,we highlight the relationship between microbiota and the therapeutic efficacy,toxicity,or side effects of commonly utilized treatments for cancer,including chemotherapy,radiotherapy,and *** that microbial factors influence the cancer treatment outcome,we further summarize some dominating microbial interventions and discuss the hidden risks of these *** review aims to provide an overview of the applications and advancements of microbes in cancer clinical relevance.

关键词： microbiome cancer diagnosis prognosis therapy

Automatic modulation recognition of radiation source signals based on two-dimensional data matrix and improved residual neural network

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Defence Technology（防务技术） 2024年第3期33卷 364-373页

作者： Guanghua Yi Xinhong Hao Xiaopeng Yan Jian dai Yangtian Liu Yanwen han Science and Technology on Electromechanical Dynamic Control Laboratory School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081China BIT Tangshan Research Institute Beijing 100081China

Automatic modulation recognition(AMR)of radiation source signals is a research focus in the field of cognitive ***,the AMR of radiation source signals at low SNRs still faces a great ***,the AMR method of radiation source signals based on two-dimensional data matrix and improved residual neural network is proposed in this ***,the time series of the radiation source signals are reconstructed into two-dimensional data matrix,which greatly simplifies the signal preprocessing ***,the depthwise convolution and large-size convolutional kernels based residual neural network(DLRNet)is proposed to improve the feature extraction capability of the AMR ***,the model performs feature extraction and classification on the two-dimensional data matrix to obtain the recognition vector that represents the signal modulation *** analysis and simulation results show that the AMR method based on two-dimensional data matrix and improved residual network can significantly improve the accuracy of the AMR *** recognition accuracy of the proposed method maintains a high level greater than 90% even at -14 dB SNR.

关键词： Automatic modulation recognition Radiation source signals Two-dimensional data matrix Residual neural network Depthwise convolution

Influence of syngas components and ash particles on the radiative heat transfer in a radiant syngas cooler

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Chinese Journal of Chemical Engineering 2024年第4期68卷 203-215页

作者： Chen han Youmin Situ Huaxing Zhu Jianliang Xu Zhenghua dai Guangsuo Yu Haifeng Liu National Energy Coal Gasification Technology Research and Development Center East China University of Science and TechnologyShanghai 200237China Shanghai Engineering Research Center of Coal Gasification East China University of Science and TechnologyShanghai 200237China

Radiant syngas cooler(RSC)is widely used as a waste heat recovery equipment in industrial *** this work,an RSC with radiation screens is established and the impact of gaseous radiative property models,gas components,and ash particles on heat transfer is investigated by the numerical simulation *** the syngas components and the pressure environment of the RSC,a modified weighted-sum-of-gray-gases model was *** modified model shows high accuracy in *** computational fluid dynamics simulation,the calculated steam production is only 0.63%in error with the industrial *** with Smith's model,the temperature decay along the axial direction calculated by the modified model is *** components are of great significance to heat recovery capacity,especially when the absorbing gas fraction is less than 10%.After considering the influence of particles,the outlet temperature and the proportion of radiative heat transfer are less affected,but the difference in steam output reaches 2.7 t·h^(-1).The particle deposition on the wall greatly reduces the heat recovery performance of an RSC.

关键词： Radiant syngas cooler Weighted-sum-of-gray-gases model Numerical simulation Particle radiation

Bifunctional core–shell co-catalyst for boosting photocatalytic CO_(2. reduction to CH_(4)

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Nano Research 2024年第3期17卷 1259-1266页

作者： Fangxu dai Mingming Zhang Jishu han Zhenjiang Li Shouhua Feng Jun Xing Lei Wang Key Laboratory of Eco-chemical Engineering Ministry of EducationCollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China College of Materials Science and Engineering Qingdao University of Science and TechnologyQingdao 266042China College of Environment and Safety Engineering Qingdao University of Science and TechnologyShandong Engineering Research Center for Marine Environment Corrosion and Safety ProtectionQingdao 266042China

Solar-light-driven CO_(2. reduction CO to CH_(4) and C2.6 is a complex process involving multiple elementary reactions and energy ***,achieving high CH_(4) activity and selectivity remains a significant ***,we integrate bifunctional Cu2. and Cu-MOF(MOF=metal-organic framework)core–shell co-catalysts(Cu2.@Cu-MOF)with semiconductor TiO_(2..Experiments and theoretical calculations demonstrate that Cu2.(Cu+facilitates charge separation)and Cu-MOF(Cu2.improves the CO_(2. adsorption and activation)in the core–shell structure have a synergistic effect on photocatalytic CO_(2. reduction,reducing the formation barrier of the key intermediate*COOH and**** photocatalyst exhibits high CH_(4) yield(366.0μmol·g^(-1)·h^(-1)),efficient electron transfer(32.3μmol·g^(-1)·h^(-1))and hydrocarbon selectivity(95.5%),which represents the highest activity of Cu-MOF-based catalysts in photocatalytic CO_(2. reduction *** work provides a strategy for designing efficient photocatalysts from the perspective of precise regulation of components.

关键词： bifunctional co-catalyst core–shell photocatalytic CO_(2.reduction

Rapid report of the December 18,2.2. M_(S)6.2.Jishishan earthquake,Gansu,China

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Earthquake Research Advances 2024年第2期4卷 14-21页

作者： Guangjie han Danqing dai Yu Li Nan Xi Li Sun China Earthquake Networks Center Beijing100045China

On December 18,2.2.,the Jishishan area in Gansu Province was jolted by a M_(S) 6.2.earthquake,which is the most powerful seismic event that occurred throughout the year in *** earthquake occurred along the NWtrending Lajishan fault(LJSF),a large tectonic transformation *** this event,China Earthquake Networks Center(CENC)has timely published several reports about seismic sources for emergency *** earthquake early warning system issued the first alert 4.9 s after the earthquake occurrence,providing prompt notification that effectively mitigated panics,injuries,and deaths of *** near real-time focal mechanism solution indicates that this earthquake is associated with a thrust *** distribution of aftershocks,the rupture process,and the recorded amplitudes from seismic monitoring and GNSS stations,all suggest that the mainshock rupture predominately propagates to the northwest *** duration of the rupture process is~12.s,and the largest slip is located at approximately 6.3 km to the NNW from the epicenter,with a peak slip of 0.12.m at~8 km *** station N002. recorded the highest instrumental intensity,which is 9.4 on the Mercalli *** estimated intensity map shows a seismic intensity reaching up to IX near the rupture area,consistent with field survey *** aftershocks(up to December 2.,2.2.)are mostly distributed in the northwest direction within~2. km of the *** earthquake caused serious casualties and house collapses,which requires further investigations into the impact of this earthquake.

关键词： Earthquake early warning Focal mechanism Rupture process Real-time intensity Coseismic deformation

Alloy as advanced catalysts for electrocatalysis:From materials design to applications

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Chinese Chemical Letters 2024年第6期35卷 104-122页

作者： Pingfan Zhang Shihuan Hong Ning Song Zhonghui han Fei Ge Gang {2. Hongjun Dong Chunmei Li Advanced Chemical Engineering Laboratory of Green Materials and Energy of Jiangsu Province Institute of Green Chemistry and Chemical TechnologySchool of Chemistry and Chemical EngineeringJiangsu UniversityZhenjiang 212013China Daqo Group Co.Ltd. Zhenjiang 212221China Key Laboratory of Groundwater Resources and Environment Ministry of EducationJilin Provincial Key Laboratory of Water Resource and EnvironmentCollege of New Energy and EnvironmentJilin UniversityChangchun 130021China

With the deep integration of electrochemical research with energy,environment,catalysis,and other fields,more and more new electrochemical catalytic reactions have entered our research *** catalysts have recently emerged as a new type of nanomaterial due to the rapid development of kinetic controlled synthesis *** materials offer several advantages over monometallic catalysts,including larger element combinations,complex geometries,bifunctional sites,and reduced use of precious *** paper provides a review of alloy electrocatalysts that are designed and prepared specifically for electrocatalytic *** use of alloy materials in electrocatalyst design is also discussed,highlighting their widespread application in this ***,various synthesis methods and synthesis mechanisms are systematically *** that,by correlating the properties of materials with the structure,relevant strategies toward advanced alloy electrocatalysts including composition regulation,size,morphology,surface engineering,defect engineering,interface engineering and strain engineering are *** addition,the important electrocatalytic applications and mechanisms of alloy electrocatalysts are described and ***,the current challenges and prospects regarding the development of alloy nanomaterials are *** review serves as a springboard from a fundamental understanding of alloy structural dynamics to design and various applications of electrocatalysts,particularly in energy and environmental sustainability.

关键词： Alloy Nanomaterial Electrocatalyst Materials design Electrocatalysis

Genome engineering of the human gut microbiome

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Journal of Genetics and Genomics 2024年第5期51卷 479-491页

作者： Linggang Zheng Juntao Shen Ruiyue Chen Yucan Hu Wei Zhao Elaine Lai-han Leung Lei dai Dr Neher's Biophysics Laboratory for Innovative Drug Discovery/State Key Laboratory of Quality Research in Chinese Medicine Macao University of Science and TechnologyTaipaMacao 999078China CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic BiologyShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China University of Chinese Academy of Sciences Beijing 100049China Cancer Center Faculty of Health ScienceUniversity of MacaoMacao 999078China MOE Frontiers Science Center for Precision Oncology University of MacaoMacao 999078China

The human gut microbiome,a complex ecosystem,significantly influences host health,impacting crucial aspects such as metabolism and *** enhance our comprehension and control of the molecular mechanisms orchestrating the intricate interplay between gut commensal bacteria and human health,the exploration of genome engineering for gut microbes is a promising ***,the complexities and diversities inherent in the gut microbiome pose substantial challenges to the development of effective genome engineering tools for human gut *** this comprehensive review,we provide an overview of the current progress and challenges in genome engineering of human gut commensal bacteria,whether executed in vitro or in situ.A specific focus is directed towards the advancements and prospects in cargo DNA delivery and high-throughput ***,we elucidate the immense potential of genome engineering methods to enhance our understanding of the human gut microbiome and engineer the microorganisms to enhance human health.

关键词： Non-model gut commensals Genomeediting reagents Cargo delivery High-throughput genome engineering