Personalized nutrition intervention improves nutritional status and quality of life of colorectal cancer survivors in the community: a randomized controlled trial
作者单位：Changning District Beixinjing Community Health Service Center 上海交通大学医学院临床研究中心
会议名称：《中国营养学会第十五届全国营养科学大会》
会议日期：2022年
学科分类：1011[医学-护理学（可授医学、理学学位）] 10[医学]
关 键 词：personalized nutritional interventions colorectal cancer cancer survivor nutritional status quality of life
摘 要：Objective: To evaluate the effects of personalized nutrition intervention combined with tele-education on the nutritional status and quality of life among colorectal cancer survivors in the community. Methods: In the randomized, parallel-controlled trial, colorectal cancer survivors who met the eligibility criteria were enrolled and randomly 1:1 assigned into nutrition intervention and routine care groups. The routine care group was received routine community follow-up twice a year. In addition to routine care group follow-up, the nutrition intervention group received personalized nutritional interventions, tele-education through WeChat for six months. The nutrition status, dietary intake, and quality of life were measured and compared between the two groups. Results: Of 60 colorectal cancer survivors were randomly assigned, 56 participants were included in the modified intention-to-treat analysis, with nutrition intervention and routine care groups. After the 6-month intervention, the nutrition group had a statistically lower PG-SGA score, higher energy intake, and protein intake compared with the routine care group. Moreover, the nutrition intervention group gained more weight(2.00 kg, 95%CI = 0.25 to 3.00) than routine care group(0.00 kg, 95%CI =-1.75 to 0.00). Meanwhile, compared with the routine care group, the nutrition intervention group had significantly higher global health status, physical functioning, role functioning, emotional functioning, cognitive functioning and social functioning(P0.05). Conclusions: Personalized nutrition interventions combined with tele-education provided by community health service centers can improve colorectal cancer survivors nutritional status and quality of life of colorectal cancer survivors. Methods In the randomized, parallel-controlled trial, colorectal cancer survivors who met the eligibility criteria were enrolled and randomly 1:1 assigned into nutrition intervention and routine care groups. The routine care group was received routine community follow-up twice a year. In addition to routine care group follow-up, the nutrition intervention group received personalized nutritional interventions, teleeducation through WeChat for six months. The nutrition status, dietary intake, and quality of life were measured and compared between the two groups. Results Of 60 colorectal cancer survivors were randomly assigned, 56 participants were included in the modified intention-to-treat analysis, with nutrition intervention and routine care groups. After the 6-month intervention, the nutrition group had a statistically lower PG-SGA score, higher energy intake, and protein intake compared with the routine care group. Moreover, the nutrition intervention group gained more weight(2.00 kg, 95%CI = 0.25 to 3.00) than routine care group(0.00 kg, 95%CI =-1.75 to 0.00). Meanwhile, compared with the routine care group,the nutrition intervention group had significantly higher global health status, physical functioning, role functioning, emotional functioning, cognitive functioning and social functioning(P0.05). Conclusion Personalized nutrition interventions combined with tele-education provided by community health service centers can improve colorectal cancer survivors nutritional status and quality of life of colorectal cancer survivors.