Isopropanol-conjugated Aloe Emodin Carbazole as Artificial Probes for Enterococcus faecalis DNA
作者单位：西南大学 School of Chemistry and Chemical EngineeringSouthwest University Jamia Millia Islamia
会议名称：《中国化学会·第十六届全国有机合成化学学术研讨会》
会议日期：2019年
学科分类：1007[医学-药学(可授医学、理学学位)] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 070303[理学-有机化学] 0703[理学-化学] 100701[医学-药物化学] 10[医学]
关 键 词：aloe emodin carbazole antibacterial probe DNA
摘 要：Structural characteristics of Aloe emodin endow natural superior resources with good interactions on DNA via multiple modes,thus Aloe emodin derivatives exhibit extensive potential in medicinal *** the basis of our previous work in carbazoles with a library of potent candidate probes for biomolecular processes,herein our interest is to combine aloe emodin scaffold with carbazole via isopropanol bridge to develop a series of new potential hybrid candidates of artificial probes for sensitive bacterial DNA in clinic.