Structural proteomics of the botulinum neurotoxin superfamily
作者单位：Department of Molecular Biology The Scripps Research Institute10550 N.Torrey Pines RdLa JollaCA 92037USA Department of Molecular Biology The Scripps Research Institute10550 N.Torrey Pines RdLa JollaCA 92037USA
会议名称：《The 4th ISGO International Conference on Structural Genomics》
会议日期：2006年
学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 07[理学]
基 金：This work was supported by the Pacific Southwest Regional Center of Excellence grant #U54 AI065359
摘 要：正Botulinum neurotoxin is one of the most deadly molecules known and also a powerful protein therapeutic for neuromuscular disorders. Initially it was believed that there were only 7 different serotypes of botulinum neurotoxin. Recently, it has been discovered that there are more likely 50-200 different subtypes of botulinum