Right ventricle material parameter estimation for healthy and patients with tetralogy of fallot using patient-specific in vivo cardiac magnetic resonance-based models with different zero-load diastole and systole morphologies
作者单位：School of Biological Science&Medical EngineeringSoutheast University Department.of Cardiac SurgeryBoston Children's HospitalDept of SurgeryHarvard Medical School Department of CardiologyBoston Children's HospitalDepartment of PediatricsHarvard Medical School Mathematical Sciences DepartmentWorcester Polytechnic Institute School of Mathematical SciencesXiamen University Department of Biomedical EngineeringWorcester Polytechnic Institute
会议名称：《第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议》
会议日期：2018年
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 10[医学]
基 金：NIH/NHLBI:R01 HL089269 NSFC:11672001,81571691
摘 要：Objective Patient-specific in vivo ventricle material parameter value determination is important for cardiovascular investigations. Ventricle active contraction caused by sarcomere shortening leads to change of ventricular zero-load configurations. A new modeling approach with different zero-load diastole and systole geometries was used to estimate right ventricle material parameter values for healthy and repaired Tetralogy of Fallot (TOF) patients for potential clinical applications. Methods Cardiac magnetic resonance (CMR) data were obtained from 6