Split G-quadruplex-combined Molecule Beacon Used for Logic Gate
作者单位：State Key Laboratory of Electroanalytical ChemistryChangchun Institute of Applied Chemistry
会议名称：《第十届全国化学生物学学术会议》
会议日期：2017年
学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术]
基 金：finanetally supported by the National Natural Science Foundation of China(No.21435005,21627808) Key Research Program of Frontier Sciences, CAS(QYZDV-SSW-SLH019)
关 键 词：logic gate split G-quadruplex logic operation
摘 要：DNA logic gate has been developed to be a prospective focus since the molecular material circuits overcome the miniaturization limitations of traditional silicon-based electronics,integrated ***,the number of logic gates accomplished by most existing DNA logic gate systems is quite limited,consequently hampering the construction of more complex iogic ***,application of intciligent detection schemes and logic circuit constructions acted as two directions in logic gate.A new platform technology is herein described with which to construct molecular logic gates by employing the split G-quadruplex-combined molecular beacon probe as a basic work *** basic logic gates（OR,AND,and XOR）,combinatorial gates（INHIB1 T-OR）.were readily achieved by taking this DNA spilt G-qwadruplex molecular beacon as a universal ***,a logic gate system for identification of multiple of three from natural numbers was established successfully by employing only this novel platform and four short single-stranded DNA.