Static coating of poly（dimethylsiloxane） with ionic complementary peptides to minimize nonspecific protein adsorption
作者单位：School of Chemistry and Chemical Engineer ing Shaanxi Normal University Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province
会议名称：《第二十届全国色谱学术报告会及仪器展览会》
会议日期：2015年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 070303[理学-有机化学] 0703[理学-化学]
关 键 词：PDMS ionic complementary peptides protein adsorption microfluidic chips
摘 要：正Surface fouling by nonspecific protein adsorption is one of the most frequently encountered problems in polymer-based microfluidic chips,resulting in substantial sample loss and low device *** the current work,a highly facile and efficient method based on ionic complementary peptide was developed for surface modification of poly（dimethyls iloxane）（PDMS）*** first demonstrate that EAR16-II can readily self-assemble into amphipathic films primarily composed of tightly packedβ-sheets in the presence of carbohydrate derivatives on both native hydrophobic and plasma-oxidized hydrophilic