Micro RNA-137 inhibits EFNB2 expression affected by a genetic variant and is expressed aberrantly in peripheral blood of schizophrenia patients
作者单位：Department of Biochemistry and Molecular Biology Xi'an Jiaotong University Health Science Center Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University)Ministry of Education Translational medicine center Honghui Hospital Xi'an Jiaotong University Health Science Center Department of Human Genetics 4 Genome Institute of Singapore Agency for Science Technology and Research (A*STAR) Department of Medicinal Chemistry and Molecular PharmacologyPurdue University Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education) Bio-X Institutes Shanghai Jiao Tong University
会议名称：《中国生物化学与分子生物学会2016年全国学术会议》
会议日期：2016年
学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学]
关 键 词：Schizophrenia MiR-137 EFNB2 SNP Regulation
摘 要：MicroRNAs(mi RNAs)are a class of endogenous and non-coding single-stranded RNAs of approximately 22 nucleotides,many of which are evolutionarily ***-wide association studies have identified a robust statistical association between the MIR137 gene and schizophrenia in Europeans,which was replicated in the Han Chinese population in a casecontrol *** the previous study,we provided evidence for a significant association between the EFNB2 gene and