Phage Display Based Bioanalysis and Biosensing
作者单位：Institute for Biosensingand College of Chemical Science and EngineeringQingdao University
会议名称：《中国化学会第30届学术年会》
会议日期：2016年
学科分类：0710[理学-生物学] 07[理学] 08[工学] 080202[工学-机械电子工程] 071007[理学-遗传学] 0802[工学-机械工程]
关 键 词：Phage display Specific probes Bioanalysis Phage ELISA Cytosensor
摘 要：Specific probes against targets can be selected from the landscape phage library f8/8 displaying random octapeptides on the pⅧ coat protein of the phage fd-tet,and demonstrating many excellent features including multivalency,stability,and high structural homogeneity.In this talk,the advanced phage clones binding with targets were screened from the landscape phage library will be addressed.Furthermore,a wide range of applications developed in our laboratory such as phage ELISA for biomarker detection,peptide microarray,nanomedicine,label-free electrochemical impedance cytosensor will be presented.Taken together,the phage display technology should become efficient and cost-effective in bioanalysis or biosensing.