CtBP promote the cancer cell migration through downregulating cholesterol synthesis
作者单位：Faculty of Health Sciences University of Macau Metabolomics Core Faculty of Health Sciences University of Macau
会议名称：《中国生物化学与分子生物学会2016年全国学术会议》
会议日期：2016年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
关 键 词：CtBP Cholesterol EMT Cancer
摘 要：Cancermetastasis kills almost 90%of patient and almost always announces the worst destination of patients once being diagnosed.How the tumor cells eventually turn to metastatic cells is still unclear but the epithelial to mesenchymal transition is believed to be essential in the metastasis process.Along this process,cells experience significant alteration in gene