INewcastle disease virus infection induces activation of the NLRP3 inflammasome
作者单位：中国农业科学院上海兽医研究所 College of Veterinary MedicineNorthwest A&F University Unit of Innate ImmunityKey Laboratory of Molecular Virology & ImmunologyInstitul Pasteur of ShanghaiShanghai Institutes for Biological SciencesChinese Academy of Sciences
会议名称：《中国畜牧兽医学会生物技术学分会暨中国免疫学会兽医免疫分会第十二次学术研讨会》
会议日期：2016年
学科分类：090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学]
基 金：国家自然科学基金项目(31530074 31372421)
摘 要：Inflammatory responses are important aspects of the innate immune system during virus *** found that Newcastle disease virus can induce inflammasome aclivalion in the human macrophage-like cell line *** replication was required for iiiflammasome activation,and small hairpin HNA knockdown expei’inienls indicated that IL-1βsecretion was me-