Ligands induce the mutual movements between the HP1 and TM4 of the glutamate transporter EAAT1
作者单位：Department of ImmunologySouthern Medical University Teaching Center of Experimental MedicineSouthern Medical University
会议名称：《生命的分子机器及其调控网络——2012年全国生物化学与分子生物学学术大会》
会议日期：2012年
学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术]
摘 要：Excitatory amino acid transporter 1(EAAT1) plays an importance role in uptaking glutam-ate from the synaptic cleft and keeping the extracellular glutamate concentration under the neurotoxic *** reentrant helical hairpin(HP) 1 is part of the intracellular gate of the *** of this intracellular gate,the transporter releases sodium and substrate to the ***