Global and Local Diffusional Motions as a Probe of the Structure and Dynamics of Membrane Proteins

作     者：Feng Gai~* Department of Chemistry,University of Pennsylvania,Philadelphia,PA 19104,USA 

会议名称：《第一届全国生物物理化学会议暨生物物理化学发展战略研讨会》

会议日期：2010年

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 07[理学] 

摘      要：正Molecular diffusions that occur on the nanosecond and longer timescales can now be easily measured,for example,using fluorescence correlation spectroscopy（FCS）.In this talk,we will show that measurements of molecular diffusivity via FCS offer a simple yet sensitive means to study the structure and dynamics of membrane proteins,and in some cases they are