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Conservation and utilization of pig resources by xenograftin...

Conservation and utilization of pig resources by xenografting to mice

作     者:Kazuhiro Kikuchi Michiko Nakai Junko Noguchi Junya Ito Naomi Kashiwazaki Hiroyuki Kaneko 

作者单位:Division of Animal SciencesNational Institute of Agrobiological SciencesTsukubaIbaraki Laboratory of Animal ReproductionSchool of Veterinary MedicineAzabu UniversitySagamiharaKanagawa 

会议名称:《中国畜牧兽医学会动物繁殖学分会第十五届学术研讨会》

会议日期:2010年

学科分类:08[工学] 0905[农学-畜牧学] 09[农学] 0836[工学-生物工程] 090501[农学-动物遗传育种与繁殖] 

基  金:supported in part by a Grants-in-Aid for Scientific Research(22380153 to K.K.and 21380715 to H.K.) from the Japanese Society for Promotion of Science 

摘      要:In vitro fertilization of in vitro matured oocytes in pigs has become the most popular method of studying gametogenesis and embryogenesis in this *** addition,because of recent advances in in vitro culture of those embryos,in vitro embryo production now enables us to generate viable embryos as successfully as for in vivo-derived embryos and with less cost and in less *** technologies contribute not only to developments in reproductive physiology and agriculture but also to conservation of porcine genetic resources. Until now,conservation of pig genetic recourses has been limited by cryopreservation of sperm and,in some cases, in vivo-derived *** aspects may decrease the general activates in ex situ conservation(gene banking) in this *** recent years,however,unique technologies such as xenografting of gonadal(testicular and ovarian) tissue into immunodeficient experimental animals,which are combined with in vitro embryo production technologies,have been developed to help conservation and utilization of gamete *** have already shown fertilizing ability and developmental ability of porcine embryos from gametes grown in ***,we discuss the possibility of conservation and utilization of pig resources by xenografting to mice.

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