Application of Diversity Oriented Synthesis （DOS） to Identification of Biologically Active Molecules

作     者：Zhen Yang Laboratory of Chemical Genomics, Shenzhen Graduate School, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education and Beijing National Laboratory for Molecular Science (BNLMS), College of Chemistry, Peking University, Beijing 100871 

会议名称：《中国化学会第26届学术年会化学生物分会场》

会议日期：2008年

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

摘      要：正Diversity-oriented synthesis （DOS） can be used to synthesize diversified molecules on a large scale. As with all large-scale experiments, this process requires a major investment in equipment, consumables and time. Therefore, careful careful design is critical. As the complexity of the libraries to be generated increases, additional considerations become important. What are the issues that should be considered when