Maspin Down-regulates the Expression of Prostate Specific Antigen in Human Prostate Cancer LNCaP Cells
作者单位：北京301医院病理科 Center for Prostate Disease ResearchUniformed Service University of Health Science Urology ServiceWalter Reed Army Medical Center
会议名称：《中华医学会病理学分会2005年学术年会》
会议日期：2005年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要：Maspin, a member of the serpin superfamily,inhibits cell mobility, invasion and metastasis in breast and prostate cancer. But the role of Maspin as a tumor suppressor is not clear because Maspin is paradoxically over - expressed in pancreatic carcinoma, ovarian carcinoma, gastric carcinoma and other carcinomas. Recent studies indicate that the nuclear Maspin may be associated with favorable clinical outcome of cancer pa-