ECM1 controls Th2 cell egress from lymph nodes through re-expression of S1P1
作者单位：Shanghai Institute of Biochemistry and Cell BiologyShanghai Institutes for Biological SciencesChinese Academy of Sciences
会议名称：《2012年中国科协海峡两岸青年科学家学术活动月——第九届海峡两岸细胞生物学学术研讨会》
会议日期：2012年
学科分类：0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种]
关 键 词：ECM1 regulate allergies asthma
摘 要：Th2 cells are differentiated from naive CD4+helper T cells,which have a crucial role in adaptive immune *** are critically involved in inflammatory diseases such as allergies and *** of Th2 cells into inflammatory tissues requires sphingosine-1-phosphate(S1P)interaction with the S1P receptor *** T cell trafficking is crucial for immunological responses,the mechanisms controlling specific