In vitro evaluation of a novel small-caliber vascular scaffold fabricated with acellular vascular matrix and Poly(Lactic-co-Glycolic Acid)
作者单位：Key Laboratory of Biorheological Science and TechnologyMinistry of EducationBioengineering CollegeChongqing University “111”Project Laboratory of Biomechanics and Tissue RepairBioengineering CollegeChongqing University "111"Project Laboratory of Biomechanics and Tissue RepairBioengineering CollegeChongqing University
会议名称：《第十届全国生物力学学术会议暨第十二届全国生物流变学学术会议》
会议日期：2012年
学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学]
基 金：supported by National Science Foundation of China(No.1010200520110021,No.1010200520110022) "111 Project" of China (No.B06023) sharing fund of Chongqing university’ s large-scale equipment
摘 要：More and more small-caliber synthetic prostheses are in demand for operations.A physiological and biochemical stability of the extracellular matrix plays a pivotal role for metabolism,function and adhesion of cells .Porcine collagen is a biologic scaffold which is most widely used for therapeutic applications due to its availability and its history of successful ***(Lactic-co-Glycolic Acid)(PLGA) exhibit a high degree of biocompatibility, better mechanical strength and degradation rate in the *** research is to fabricate a novel small-calibervascular graft,comprising acellular vascular matrix(AVM) of swine origin and *** mechanical or biological characterizations of AVM-PLGA were tested in vitro by methods of histological examina-