The Effect of Heme on the Thermal Stability of Myoglobin under Conditions of Amyloidsis
作者单位:Key Laboratory for Molecular Enzymology&Engineeringthe Ministry of Education(Jilin University)Changchun 130021China
会议名称:《第二届全国“跨学科蛋白质研究”学术讨论会》
会议日期:2008年
学科分类:0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术]
关 键 词:apomyoglobin myoglobin prothetic group heme amyloid fibril DSC ATR-IR CD ThT.
摘 要:Prosthetic group affects the holoprotein stability and the passway of protein folding/*** find the heme effect under the condition of ***,DSC,ATR-FTIR,CD and ThT fluorescence assay have been adopted to study the kinetics of amyloidsis of apomyoglobin as well as myoglobin,especially in the early stage (the first 120min).The results show that heme has