Structural study of receptor recognition mechanism of a mouse pheromone ESPl
作者单位:Faculty of Life SciencesKumamoto UniversityKumamotoJapan Graduate School of Agricultural and Life SciencesThe University of TokyoTokyoJapan Graduate School of Pharmaceutical SciencesThe University of TokyoTokyoJapan
会议名称:《第十七届国际生物物理大会;第十二届中国生物物理大会》
会议日期:2011年
学科分类:0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术]
关 键 词:mouse pheromone ESP1 GPCR molecular recognition NMR
摘 要:Pheromones are species-specific chemical signals that regulate a wide range of social and sexual behaviours in many *** vomeronasal organ(VNO) detects the pheromonal information via vomeronasal sensory neurons(VSNs) in *** have identified a male-specific peptide ESPl(exocrine-gland-secreting peptide 1) secreted into tear fluids that stimulates female *** ESPl signal is received,the vomeronasal type 2