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Molecular Biology and Functional Implications of Human Siali...

Molecular Biology and Functional Implications of Human Sialidases

作     者:Guido Tettamanti 

作者单位:Department of Medical ChemistryBiochemistry and BiotechnologyThe Medical SchoolUniversity of MilanVia F.lli Cervi 9320090 SegrateMilanItaly 

会议名称:《第八届全国复合糖生物化学与分子生物学学术会议》

会议日期:2004年

学科分类:0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

摘      要:Sialidases are expressed in viruses,bacteria,protozoa and *** and bacterial sialidases displayabom 3 5%homology in their primary structure,and share some specific motifs like the six four-strandedantiparallel β-sheets arranged as the blades of a propeller,the F(Y)RIP motiflocated toward the aminoterminalregion,the repetitive motif SXDXGXXT/W in the active site *** some *** mammalian

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