An overview of polymeric nanomicelles in clinical trials and on the market

作     者：Xue Zheng Jizhen Xie Xing Zhang Weiting Sun Heyang Zhao Yantuan Li Cheng Wang Xue Zheng;Jizhen Xie;Xing Zhang;Weiting Sun;Heyang Zhao;Yantuan Li;Cheng Wang

作者机构：Key Laboratory of Marine DrugsChinese Ministry of EducationSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China Shandong Center for Food and Drug Evaluation and CertificationJi'nan 250013China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2021年第32卷第1期

页      面：243-257页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 10[医学] 0702[理学-物理学] 

基　　金：financially supported by Fundamental Research Funds for the Central Universities(No.201964018) National Natural Science Foundation of China(No.31872754) Qingdao Program for Original Innovation and Fundamental Research(No.18-2-2-73-jch) 

主　　题：Polymeric micelles Drug delivery Preparation Clinical application Challenges 

摘      要：Polymeric nanomedicine is a promising and rapidly evolving *** the different polymeric carriers,polymeric micelle(PM) with nanoscale size exhibit potent physical and biological advantages including excellent solubility and pharmacokinetics,enhanced efficacy and lower *** has garnered increasing intere st in research and in the *** review will highlight the clinical outcomes of several PM-based formulations,and further summarized their preparation methods,strengths and challenges.