Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D2-muscarinic acetylcholine M1 receptor heteromer

作     者：RenéA.J.Crans Francisco Ciruela René A.J.Crans;Francisco Ciruela

作者机构：Laboratory of ToxicologyDepartment of BioanalysisGhent UniversityGhentBelgium Unitat de FarmacologiaDepartament Patologia i Terapèutica ExperimentalFacultat de Medicina i Ciències de la SalutIDIBELLUniversitat de BarcelonaL’Hospitalet de LlobregatBarcelonaSpain Institut de NeurociènciesUniversitat de BarcelonaBarcelonaSpain 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2021年第16卷第7期

页      面：1406-1408页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the Fonds Wetenschappelijk Onderzoek(FWOSBO, Grant number 140028) Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación/FEDER(Grant number SAF2017-87349-R) Generalitat de Catalunya(Grant numbers 2017 SGR1604 and 2017 SGR595) Fundació la Marató de TV3(grant number 20152031) supported by an FWO Travel Grant for a Long Stay Abroad(grant number V420718N) an EMBO Short-Term Fellowship(grant number 6735)。 

主　　题：al. Dopamine dopamine 

摘      要：The striatum is the primary input structure of the basal ganglia, which participates in motivational and goaldirected behaviors(Pisani et al., 2007).In physiological conditions, local cholinergic interneurons(ChIs) and dopaminergic afferents modulate basal ganglia output through striatal projection neurons.