Biodegradable materials for bone defect repair

作     者：Shuai Wei Jian-Xiong Ma Lai Xu Xiao-Song Gu Xin-Long Ma Shuai Wei;Jian-Xiong Ma;Lai Xu;Xiao-Song Gu;Xin-Long Ma

作者机构：Tianjin HospitalTianjin UniversityTianjin 300211China Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury RepairKey Laboratory of Neuroregeneration of Jiangsu and Ministry of EducationNantong UniversityNantongJiangsu 226001China 

出 版 物：《Military Medical Research》 (军事医学研究（英文版）)

年 卷 期：2021年第8卷第2期

页      面：202-229页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：supported by grants from the National Natural Science Foundation of China(11772226,81871777 and 81572154) the Tianjin Science and Technology Plan Project(18PTLCSY00070,16ZXZNGX00130) grants awarded to Xiao-Song Gu by the National Natural Science Foundation of China(31730031 and L1924064) 

主　　题：Biodegradable materials Bone defects Bone repair Intelligent material Modular fabrication 

摘      要：Compared with non-degradable materials,biodegradable biomaterials play an increasingly important role in the repairing of severe bone defects,and have attracted extensive attention from *** the treatment of bone defects,scaffolds made of biodegradable materials can provide a crawling bridge for new bone tissue in the gap and a platform for cells and growth factors to play a physiological role,which will eventually be degraded and absorbed in the body and be replaced by the new bone *** biodegradable materials include polymers,ceramics and metals,which have been used in bone defect repairing for many *** these materials have more or fewer shortcomings,they are still the cornerstone of our development of a new generation of degradable *** the rapid development of modern science and technology,in the 21 st century,more and more kinds of new biodegradable materials emerge in endlessly,such as new intelligent micro-nano materials and cell-based *** the same time,there are many new fabrication technologies of improving biodegradable materials,such as modular fabrication,3 D and 4 D printing,interface reinforcement and *** review will introduce various kinds of biodegradable materials commonly used in bone defect repairing,especially the newly emerging materials and their fabrication technology in recent years,and look forward to the future research direction,hoping to provide researchers in the field with some inspiration and reference.