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Chemical Constituents in E-Cigarette Liquids and Aerosols

Chemical Constituents in E-Cigarette Liquids and Aerosols

作     者:Mohd Naeem Mohd Naeem Sharifah Mazrah Sayed Mohamed Zain Catrina Ng Mohd Fairulnizal Md. Noh Mohd Naeem Mohd Naeem;Sharifah Mazrah Sayed Mohamed Zain;Catrina Ng;Mohd Fairulnizal Md. Noh

作者机构:Nutrition Metabolism and Cardiovascular Research Centre Institute for Medical Research (IMR) National Institutes of Health Ministry of Health Malaysia (MOH) Shah Alam Selangor Malaysia Environmental Health Research Centre Institute for Medical Research (IMR) National Institutes of Health Ministry of Health Malaysia (MOH) Shah Alam Selangor Malaysia Perkin Elmer Sdn Bhd Petaling Jaya Selangor Malaysia 

出 版 物:《Journal of Environmental Protection》 (环境保护(英文))

年 卷 期:2020年第11卷第9期

页      面:664-681页

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主  题:E-Cigarette Volatile Organic Compounds Aerosols E-Liquids Constituents 

摘      要:Electronic cigarettes (e-cigarettes, EC) form an aerosol from the heating element and liquid-containing cartridge. The heating element aerosolizes the refill solutions (e-liquids) when the power source of e-cigarette is pressed. E-liquids consist of combinations of propylene glycol, glycerine, nicotine and flavouring ingredients. Puffing activates the battery-operated heating element in the atomizer and will produce smoke that is similar to conventional cigarette (CC). This study evaluated the chemical composition of e-liquid and aerosol samples available in Malaysia. We analyzed the volatile organic compounds in e-liquids and the aerosols samples from EC using gas chromatography mass spectrometer. Seventy-two EC e-liquids were analyzed through different flavours from more than 60 brands. Samples consisted of 32 nicotine-free (0 mg) and 40 nicotine-containing refill solutions (3 - 12 mg). Overall, 116 compounds were identified from EC e-liquids. On the other hand, 275 compounds were identified from their resultant aerosol samples. There were 42 compounds found in both e-liquids and aerosols. Seven compounds were only found in e-liquids and 38 compounds were only found in aerosols. Propylene glycol was found in all of the e-liquid and aerosol samples. Glycerin was found in 99% of the e-liquid and 100% of aerosol samples. At least 60% of the EC e-liquids and the resultant aerosol contain piperidine, butanoic acid ethyl ester and nicotine. It was also found that at least 9 out of 35 nicotine free labeled e-liquids contain nicotine. Some of these compounds were known to be detrimental to health and were detected in aerosol although they were not present in e-liquids. While some of the compounds are flavouring ingredients, it is necessary to evaluate its long-term effects on EC users.

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