A Novel Route to Synthesize N,N-Dimethyl Arylmethylamines from Aryl Aldehydes, Hexamethylenetetramine and Hydrogen

作     者：Zhengang Ke Bo Yu Yunyan Wu Yanfei Zhao Peng Yang Shien Guo Zhimin Liu Zhengang Ke;Bo Yu;Yunyan Wu;Yanfei Zhao;Peng Yang;Shien Guo;Zhimin Liu

作者机构：Beijing National Laboratory for Molecular SciencesKey Laboratory of ColloidInterface and ThermodynamicsCAS Research/Education Centre for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of SciencesBeijing 100049China Physical Science LaboratoryHuairou National Comprehensive Science CenterBeijing 101407China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2020年第38卷第8期

页      面：842-846页

核心收录：

学科分类：07[理学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was financially supported by the Beijing Municipal Science&Technology Commission(No.Z191100007219009) Chinese Academy of Sciences(Grant No.QYZDY-SSW-SLH013). 

主　　题：synthesis. amines synthesize 

摘      要：Developing simple and green routes to access valuable chemicals is of significance.Herein,we present a green and novel route to synthesize N,N-dimethyl arylmethylamines(DAMAs)from hexamethylenetetramine(HMTA)and aryl aldehydes in the presence of hydrogen,and a series of DAMAs can be obtained in good yields.This approach opens the precedent for HMTA as N,N-dimethylamine source to synthesize chemicals with N,N-dimethylamine group,which has promising applications for N-containing chemicals synthesis.