Recent advances in nickel-catalyzed reductive hydroalkylation and hydroarylation of electronically unbiased alkenes
Recent advances in nickel-catalyzed reductive hydroalkylation and hydroarylation of electronically unbiased alkenes作者机构:Hefei National Laboratory for Physical Sciences at the MicroscaleCAS Key Laboratory of Urban Pollutant ConversionAnhui Province Key Laboratory of Biomass Clean EnergyiChEMUniversity of Science and Technology of ChinaHefei 230026China
出 版 物:《Science China Chemistry》 (中国科学(化学英文版))
年 卷 期:2020年第63卷第11期
页 面:1586-1600页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金:This work was supported by the National Natural Science Foundation of China(21732006 21702200 51821006 51961135104)and the Fundamental Research Funds for the Central Universities
主 题:nickel electronically unbiased alkenes C-C bond formation reductive hydroalkylation reductive hydroarylation
摘 要:The use of simple and easily available feedstock to quickly and efficiently obtain compounds with complex molecular structures through the transition-metal-catalyzed construction of C(sp3)–C bonds has important *** traditional C(sp3)–C coupling reagents,alkylmetallic reagents often have limitations such as air and moisture sensitivity and difficulties in ***-catalyzed reductive olefin hydrocarbonation reactions use alkenes to replace organometallic reagents,reduce the synthesis steps,improve the functional group compatibility,and expand the substrate *** minireview discusses important progress in the hydroalkylation and hydroarylation of electronically unbiased alkenes in recent years and describes the key mechanism and applications.