Recent advances in nickel-catalyzed reductive hydroalkylation and hydroarylation of electronically unbiased alkenes

作     者：Xiao-Xu Wang Xi Lu Yan Li Jia-Wang Wang Yao Fu Xiao-Xu Wang;Xi Lu;Yan Li;Jia-Wang Wang;Yao Fu

作者机构：Hefei National Laboratory for Physical Sciences at the MicroscaleCAS Key Laboratory of Urban Pollutant ConversionAnhui Province Key Laboratory of Biomass Clean EnergyiChEMUniversity of Science and Technology of ChinaHefei 230026China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2020年第63卷第11期

页      面：1586-1600页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was supported by the National Natural Science Foundation of China(21732006 21702200 51821006 51961135104)and the Fundamental Research Funds for the Central Universities 

主　　题：nickel electronically unbiased alkenes C-C bond formation reductive hydroalkylation reductive hydroarylation 

摘      要：The use of simple and easily available feedstock to quickly and efficiently obtain compounds with complex molecular structures through the transition-metal-catalyzed construction of C(sp3)–C bonds has important *** traditional C(sp3)–C coupling reagents,alkylmetallic reagents often have limitations such as air and moisture sensitivity and difficulties in ***-catalyzed reductive olefin hydrocarbonation reactions use alkenes to replace organometallic reagents,reduce the synthesis steps,improve the functional group compatibility,and expand the substrate *** minireview discusses important progress in the hydroalkylation and hydroarylation of electronically unbiased alkenes in recent years and describes the key mechanism and applications.