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Local aneurysmal dilatation mimicking stent malapposition and concurrent vulnerable plaque within neointima of normal lumen after drug-eluting stent implantation: primary new findings from optical coherence tomography

Local aneurysmal dilatation mimicking stent malapposition and concurrent vulnerable plaque within neointima of normal lumen after drug-eluting stent implantation: primary new findings from optical coherence tomography

作     者:GUO Yuan-lin YANG Yue-jin GAO Zhan QIAN Jie 

作者机构:Clinical and Research Center for Coronary DiseaseFu Wai HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100037China 

出 版 物:《Chinese Medical Journal》 (中华医学杂志(英文版))

年 卷 期:2012年第125卷第6期

页      面:1186-1188页

核心收录:

学科分类:0821[工学-纺织科学与工程] 0905[农学-畜牧学] 08[工学] 09[农学] 090501[农学-动物遗传育种与繁殖] 082104[工学-服装设计与工程] 

主  题:drug-eluting stent stent malapposition vulnerable plaque optical coherence tomography 

摘      要:Very late stent thrombosis is a life-threatening complication of implantation of drug-eluting stent (DES). The mechanisms are still unidentified. Stent malapposition is supposed to be one debated reason. Here we report a case of 33 months after DES implanted. Observed by optical coherence tomography, we detected a lipid-rich plaque with defective fibrous cap within the neointima and many local aneurysmal dilatations between stent struts, which mimic "malapposition" on the angiogram. These indicated that vulnerable plaque hidden in the neointima at the stent segment might be a potential mechanism of very late stent thrombosis after DES implantation.

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