The journey of multifunctional bone scaffolds fabricated from traditional toward modern techniques

作     者：Ashkan Bigham Firoozeh Foroughi Erfan Rezvani Ghomi Mohammad Rafienia Rasoul Esmaeely Neisiany Seeram Ramakrishna Ashkan Bigham;Firoozeh Foroughi;Erfan Rezvani Ghomi;Mohammad Rafienia;Rasoul Esmaeely Neisiany;Seeram Ramakrishna

作者机构：Department of BiomaterialsTissue Engineering and NanotechnologySchool of Advanced Technologies in Medicine(ATiM)Isfahan University of Medical SciencesIsfahanIran Department of Materials Science and EngineeringFaculty of EngineeringNational University of Singapore9 Engineering Drive 1Singapore 117576Singapore Department of Mechanical EngineeringCenter for Nanofibers and NanotechnologyNational University of SingaporeSingapore 119260Singapore Biosensor Research CenterIsfahan University of Medical SciencesIsfahanIran Department of Materials and Polymer EngineeringFaculty of EngineeringHakim Sabzevari University*** SabzevarIran 

出 版 物：《Bio-Design and Manufacturing》 (生物设计与制造（英文）)

年 卷 期：2020年第3卷第4期

页      面：281-306页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

主　　题：Multifunctional scaffolds Bone cancer Fabrication techniques Bone tissue regeneration 

摘      要：As a bone scaffold,meeting all basic requirements besides dealing with other bone-related issues-bone cancer and accelerated regeneration-is not expected from traditional scaffolds,but a newer class of scaffolds called *** a clinical point of view,being a multifunctional scaffold means reducing in healing time,direct costs-medicine,surgery,and hospitalization-and indirect costs-loss of mobility,losing job,and *** main aim of the present review is following the multifunctional bone scaffolds trend to deal with both bone regeneration and cancer *** consideration is given to different fabrication techniques which have been applied to yield these materials spanning from traditional to modern ***,the hierarchical structure of bone plus bone cancers and available medicines to them are introduced to familiarize the potential reader of review with the pluri-disciplinary essence of the ***,a brief discussion relating to the future trend of these materials is provided.