Approaches to promoting bone marrow mesenchymal stem cell osteogenesis on orthopedic implant surface

作     者：Shi-Cheng Huo Bing Yue 

作者机构：Department of Bone and Joint SurgeryRenji HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China 

出 版 物：《World Journal of Stem Cells》 (世界干细胞杂志（英文版）（电子版）)

年 卷 期：2020年第12卷第7期

页      面：545-561页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：Supported by Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support No.20161423 

主　　题：Bone marrow mesenchymal stem cells Osseointegration Orthopedic implant Biofunctionalization 

摘      要：Bone marrow-derived mesenchymal stem cells(BMSCs)play a critical role in the osseointegration of bone and orthopedic ***,osseointegration between the Ti-based implants and the surrounding bone tissue must be improved due to titanium’s inherent *** modification stands out as a versatile technique to create instructive biomaterials that can actively direct stem cell ***,we summarize the current approaches to promoting BMSC osteogenesis on the surface of titanium and its *** will highlight the utilization of the unique properties of titanium and its alloys in promoting tissue regeneration,and discuss recent advances in understanding their role in regenerative *** aim to provide a systematic and comprehensive review of approaches to promoting BMSC osteogenesis on the orthopedic implant surface.