Neurogenesis similarities in different human adult stem cells

作     者：Carlos Bueno Salvador Martínez Carlos Bueno;Salvador Martínez

作者机构：Instituto de Neurociencias de Alicante(UMH-CSIC)San JuanAlicanteSpain 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2021年第16卷第1期

页      面：123-124页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 

基　　金：funded by Instituto de Salud Carlos III through the project “RD16/001/0010”(Co-funded by European Regional Development Fund/European Social Fund)“Investing in your future”) Spanish MINECO/AEI/FEDER (SAF2017-83702-R) 

主　　题：injuries ventricular adult 

摘      要：Human neurological disorders and spinal cord injuries are caused by a loss of neurons and glial cells in the brain or spinal *** proof-ofprinciple of cell therapy is that replacing damaged cells with new healthy ones will restore the lost *** and manipulating autologous neural stem cells(NSCs)could provide an ideal source of cells for use in cell replacement and the transfer of genes to a diseased central nervous *** are immature cells present,not only during embryonic development,but also in the adult brain of all mammalian species,including *** presence of NSCs in the adult mammalian brain has been described in two neurogenic niches,the ventricular-subventricular zone(V-SVZ)of the anterolateral ventricle wall and the subgranular zone of the hippocampal dentate ***,NSCs are defined as self-renewing multipotent cells that can generate neurons,astrocytes and *** major barrier to isolating adult NSCs in humans is the inaccessibility of living *** this reason,an enormous effort has been made to derive neurons from human adult stem cells isolated from various tissue sources.