Large-scale study of long non-coding RNA functions based on structure and expression features

作     者：ZHAO Yi WANG Jian CHEN XiaoWei LUO HaiTao ZHAO YunJie XIAO Yi CHEN RenSheng 

作者机构：Bioinformatics Research GroupAdvanced Computing Research LaboratoryInstitute of Computing TechnologyChinese Academy ofSciences Department of PhysicsHuazhong University of Science and Technology Laboratory of Bioinformatics and Non-coding RNAInstitute of BiophysicsChinese Academy of Sciences 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2013年第56卷第10期

页      面：953-959页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 081401[工学-岩土工程] 08[工学] 0817[工学-化学工程与技术] 0814[工学-土木工程] 

基　　金：supported by the National High Technology Research and Development Program of China(2012AA020402) National Natural Science Foundation of China(11074084,30970558) 

主　　题：non-coding RNA structure expression function 

摘      要：Mammals and other complex organisms can transcribe an abundance of long non-coding RNAs(lncRNAs)that fulfill a wide variety of regulatory roles in many biological *** roles,including as scaffolds and as guides for protein-coding genes,mainly depend on the structure and expression level of *** this review,we focus on the current methods for analyzing lncRNA structure and expression,which is basic but necessary information for in-depth,large-scale analysis of lncRNA functions.